Safe use of granisetron as an antiemetic after skin prick, oral, and intravenous challenge tests is presented. We present this case to emphasize that ondansetron hydrochloride may cause a serious anaphylactic reaction. [ncbi.nlm.nih.gov]

• Intravenous Administration

  J Allergy Clin Immunol 2013;132:1219-1220] documented the efficacy of the intravenous administration of ondansetron in children with acute symptoms due to food protein-induced enterocolitis syndrome (FPIES). [ncbi.nlm.nih.gov]

  2 minutes through a peripheral intravenous catheter Active Comparator: Promethazine Promethazine 10 mg intravenous administration Drug: Promethazine 12.5 mg intravenous dose administered over 2 minutes through a peripheral intravenous catheter Placebo [clinicaltrials.gov]

• Agonal Respiration

  After intravenous fluids, morphine, antibiotics, and 2 doses of ondansetron, the patient became unresponsive with agonal respirations and a wide complex tachycardia consistent with ventricular tachycardia. [ncbi.nlm.nih.gov]

• Akathisia

  Patients in adjunctive ondansetron therapy also experienced significantly lower incidence and severity of parkinsonism and akathisia as well as fewer behavioral hyperactivity, cardiac, and gastrointestinal side effects. [ncbi.nlm.nih.gov]

  However, in adults, promethazine is less effective than prochlorperazine. 24 Data from adults suggest that drowsiness (38 percent) 24 and akathisia (44 percent) 25 are common adverse events. [doi.org]

• Decerebrate Posturing

  Upon emergence from an uneventful general anesthetic, the patient exhibited cogwheel rigidity with decerebrate posturing and a markedly irregular respiratory rate. This prohibited extubation and prompted an unplanned intensive care unit admission. [ncbi.nlm.nih.gov]

• Mydriasis

  Reported symptoms included somnolence, agitation, tachycardia, tachypnea, hypertension, flushing, mydriasis, diaphoresis, myoclonic movements, horizontal nystagmus, hyperreflexia, and seizure. [dailymed.nlm.nih.gov]

• Choreoathetoid Movements

  Tardive dyskinesia consists of abnormal, involuntary, irregular choreoathetoid movements of the muscles of the head, limbs, and trunk and often is irreversible (1). Several different suppressive agents have been tried with limited success (2). [ajp.psychiatryonline.org]

• Abnormal Involuntary Movement

  Tardive dyskinesia had been stable for at least 3 months before entry to the study as measured by Abnormal Involuntary Movement Scale (AIMS) (6) scores. [ajp.psychiatryonline.org]

Undergone standardised workup to exclude the following alternative diagnoses 5.1. Microscopic colitis (colonoscopy or flexible sigmoidoscopy) 5.2. [isrctn.com]

CONCLUSIONS: A single dose of ondansetron is superior to bromopride and metoclopramide in preventing vomiting six hours and 24h following treatment. [ncbi.nlm.nih.gov]

OUTCOME AND PROGNOSIS Short-term outcomes Nausea and vomiting of pregnancy — Although the maternal course can be long and tedious [ 96 ], nausea and vomiting is typically not associated with adverse pregnancy outcomes. [web.archive.org]

We relate a patient who presents with hypokalemia of unknown etiology, with evidence suggesting a possible relationship to ondansetron. We also present a proposed mechanism for this phenomenon. [ncbi.nlm.nih.gov]

Liver failure and death have been reported in patients with cancer receiving potentially hepatotoxic/cytotoxic chemotherapy and antibiotics ; however, the etiology of liver failure is unknown. [ Ref ] Common (1% to 10%): Asymptomatic increases in AST/ [drugs.com]

In a negative control analysis, we assessed the risk of malformations in women who filled their first ondansetron prescription in gestational months 5 to 8, which is after the etiologically relevant window. [jamanetwork.com]

Epidemiology, pathophysiology and approaches to prevention and management. Drugs. 2001 ; 61(15): 2193 – 2205. Google Scholar Medline ISI 2. Alfonsi, P. Postanaesthic shivering. [doi.org]

Author information 1 Department of Epidemiology, Graduate School of Public Health, the Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Magee Womens Hospital of the University of Pittsburgh Medical Center, the Department [ncbi.nlm.nih.gov]

Coding of drug information in the National Birth Defects Prevention Study used the Slone Drug Dictionary under license from the Slone Epidemiology Center of Boston University. Financial Disclosure Dr. [journals.lww.com]

A study from the Slone Epidemiology Center at Boston University, in collaboration with the Centers for Disease Control and Prevention (CDC), found that taking ondansetron during early pregnancy did not appear to increase the chance of having a baby with [cdc.gov]

Epidemiology, pathophysiology and approaches to prevention and management. Drugs. 2001 ; 61(15): 2193 – 2205. Google Scholar Medline ISI 2. Alfonsi, P. Postanaesthic shivering. [doi.org]

To present a case of asystole during spinal anesthesia that responded to atropine and ondansetron and to discuss the possible pathophysiology with special emphasis on the Bezold-Jarisch reflex and the role of 5-HT3 receptors in mediating bradycardia and [ncbi.nlm.nih.gov]

Ludolph, Nondopaminergic Neurotransmission in the Pathophysiology of Tourette Syndrome, Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome, 10.1016/B978-0-12-411546-0.00004-4, (95-130), (2013). [oadoi.org]

However, palonosetron was more efficacious than ondansetron in the prevention of vomiting after laparoscopic surgery. [ncbi.nlm.nih.gov]