Safe use of granisetron as an antiemetic after skin prick, oral, and intravenous challenge tests is presented. We present this case to emphasize that ondansetron hydrochloride may cause a serious anaphylactic reaction. [ncbi.nlm.nih.gov]

• Intravenous Administration

  RESULTS: 49 studies are included with a total of 53 drugs. 15 drugs were found compatible administered with ondansetron in a clinical routine concentration range in intravenous administration. [ncbi.nlm.nih.gov]

  2 minutes through a peripheral intravenous catheter Active Comparator: Promethazine Promethazine 10 mg intravenous administration Drug: Promethazine 12.5 mg intravenous dose administered over 2 minutes through a peripheral intravenous catheter Placebo [clinicaltrials.gov]

• Impulsivity

  Tourniquet pain is thought to be mediated by impulse propagation via small, unmyelinated, slow-conducting C fibers. The duration of the tourniquet time is directly proportional to the onset of tourniquet pain. [ncbi.nlm.nih.gov]

• Akathisia

  Patients in adjunctive ondansetron therapy also experienced significantly lower incidence and severity of parkinsonism and akathisia as well as fewer behavioral hyperactivity, cardiac, and gastrointestinal side effects. [ncbi.nlm.nih.gov]

  However, in adults, promethazine is less effective than prochlorperazine. 24 Data from adults suggest that drowsiness (38 percent) 24 and akathisia (44 percent) 25 are common adverse events. [doi.org]

• Encephalopathy

  We treated a patient who developed transient multifocal encephalopathy with extrapyramidal symptoms (oromandibular dystonia, oculogyric crisis, and limb dystonia) in temporal proximity to ondansetron administration on emergence from general anesthesia [ncbi.nlm.nih.gov]

• Decerebrate Posturing

  Upon emergence from an uneventful general anesthetic, the patient exhibited cogwheel rigidity with decerebrate posturing and a markedly irregular respiratory rate. This prohibited extubation and prompted an unplanned intensive care unit admission. [ncbi.nlm.nih.gov]

Undergone standardised workup to exclude the following alternative diagnoses 5.1. Microscopic colitis (colonoscopy or flexible sigmoidoscopy) 5.2. [isrctn.com]

CONCLUSIONS: A single dose of ondansetron is superior to bromopride and metoclopramide in preventing vomiting six hours and 24h following treatment. [ncbi.nlm.nih.gov]

Anti-nausea - 24 mg 30 minutes before treatment, then 8 mg every 8 hours. Film - 8 mg 30 minutes before treatment, then 8 mg every 8 hours. Children 4-11 take 4 mg 30 minutes before treatment, 4 mg 8 hours later, then 4 mg every 8 hours. [md-health.com]

If this treatment is started early enough then further treatment may not be needed. [pregnancysicknesssupport.org.uk]

We relate a patient who presents with hypokalemia of unknown etiology, with evidence suggesting a possible relationship to ondansetron. We also present a proposed mechanism for this phenomenon. [ncbi.nlm.nih.gov]

Liver failure and death have been reported in patients with cancer receiving potentially hepatotoxic/cytotoxic chemotherapy and antibiotics ; however, the etiology of liver failure is unknown. [ Ref ] Common (1% to 10%): Asymptomatic increases in AST/ [drugs.com]

In a negative control analysis, we assessed the risk of malformations in women who filled their first ondansetron prescription in gestational months 5 to 8, which is after the etiologically relevant window. [jamanetwork.com]

Epidemiology, pathophysiology and approaches to prevention and management. Drugs. 2001 ; 61(15): 2193 – 2205. Google Scholar | Medline | ISI 2. Alfonsi, P. Postanaesthic shivering. [doi.org]

Coding of drug information in the National Birth Defects Prevention Study used the Slone Drug Dictionary under license from the Slone Epidemiology Center of Boston University. Financial Disclosure Dr. [journals.lww.com]

Author information 1 Department of Epidemiology, Graduate School of Public Health, the Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Magee Womens Hospital of the University of Pittsburgh Medical Center, the Department [ncbi.nlm.nih.gov]

A study from the Slone Epidemiology Center at Boston University, in collaboration with the Centers for Disease Control and Prevention (CDC), found that taking ondansetron during early pregnancy did not appear to increase the chance of having a baby with [cdc.gov]

Epidemiology, pathophysiology and approaches to prevention and management. Drugs. 2001 ; 61(15): 2193 – 2205. Google Scholar | Medline | ISI 2. Alfonsi, P. Postanaesthic shivering. [doi.org]

To present a case of asystole during spinal anesthesia that responded to atropine and ondansetron and to discuss the possible pathophysiology with special emphasis on the Bezold-Jarisch reflex and the role of 5-HT3 receptors in mediating bradycardia and [ncbi.nlm.nih.gov]

Postanaesthetic shivering: epidemiology, pathophysiology, and approaches to prevention and management. Drugs 2001; 61 :2193–205. 3. Marashi SM, Soltani-Omid S, Soltani Mohammadi S, Aghajani Y, Movafegh A. [nature.com]

However, palonosetron was more efficacious than ondansetron in the prevention of vomiting after laparoscopic surgery. [ncbi.nlm.nih.gov]