Presentation
When present, symptoms (fever, nausea, abdominal pain, and myalgias) were mild. Eosinophilia occurred in all infected persons. [ncbi.nlm.nih.gov]
In conclusion, in this study we present 13 new cases of human oesophagostorniasis. [kundoc.com]
Clinical Presentation Most infections are asymptomatic. Most pathologic manifestations result from inflammation and intermittent obstruction of the biliary ducts. [cdc.gov]
Case description A 35-year-old Dutch woman presented with fever, without localising symptoms. Laboratory tests showed pronounced eosinophilia. Microscopy of the faeces showed a liver fluke egg. [ntvg.nl]
Entire Body System
- Fishing
It is transmitted from freshwater snails to fish and then to fish-eating mammals, including humans, in which it causes opisthorchiasis. [ncbi.nlm.nih.gov]
[…] after consumption of raw freshwater fish caught in Italy. [ntvg.nl]
In the August 2007 outbreak, the fish had been frozen at –10°C for 3 days, which did not completely kill the metacercariae. Even if fish are frozen in a home freezer, there is no way of knowing the internal temperature of the fish. [doi.org]
- Inflammation
Already in the early stages of the experiment, we observed extensive periductal fibrosis, active inflammation, proliferation of the bile duct, bile duct dysplasia and egg granulomas. [pubag.nal.usda.gov]
Increased levels of co-stimulatory molecules as CD86 on DC after helminth stimulation with O.f. might suppress airway inflammation in BA. Dentritic cell Immunosuppression Infections © 2012 ERS [erj.ersjournals.com]
However, various histopathogical features including intense inflammation, fibrosis, biliary and goblet cell hyperplasia and dysplasia occurred earlier in the OF group. [ncbi.nlm.nih.gov]
The long-lived flukes cause long-lasting chronic inflammation of the bile ducts and this produces epithelial hyperplasia, periductal fibrosis, and bile duct dilatation. [eol.org]
- Chronic Infection
Chronic infection may lead to severe hepatobiliary morbidity. According to surgical and experimental reports, long-term infestation might significantly increase the risk for cholangiocarcinoma (CCA). [ncbi.nlm.nih.gov]
- Anemia
Severe anemia and liver damage may also incapacitate the infected person for 1-2 months. [wikidoc.org]
Blood tests showed anemia and increased levels of ESR and increased alkaline phosphatase. [ajtmh.org]
- Weight Loss
Patients with acute infection have signs/symptoms ranging from fever to hepatitis-like signs/symptoms (e.g., pain in upper right abdominal quadrant, weakness, fatigue, loss of appetite, diarrhea, weight loss); sign/symptom onset occurs ≈2–3 weeks after [ncbi.nlm.nih.gov]
The most common initial symptoms were fever, weakness, loss of appetite, weight loss, jaundice, and abdominal pain. [ajtmh.org]
Medical history: A 29year old female from Tomsc, Sibiri a, presented with a longterm history of ubiquitous abdominal pain and weight loss of ten kilogram within the last year. She also reported to be allergic to many substances. [kundoc.com]
Cardiovascular
- Hypertension
A family history of cardiovascular disease, smoking, hypertension or diabetes was elicited, and serum total cholesterol levels examined. [ncbi.nlm.nih.gov]
Tumor in the right lobe of liver with bile hypertension, involving biliary cyst and defeat of regional lymphatic nodes. (A) Mass-like enlargement with unclear contours; (B) enlarged intrahepatic bile ducts. [ajtmh.org]
Liver, Gall & Pancreas
- Jaundice
The most common initial symptoms were fever, weakness, loss of appetite, weight loss, jaundice, and abdominal pain. [ajtmh.org]
Opisthorchiasis is characterized by hepatosplenomegaly, abdominal tenderness, eosinophilia, chills, and fever (2); left untreated, it can lead to obstructive jaundice, cholangitis, cholecystitis, and intra-abdominal masses (1,2,4). [ncbi.nlm.nih.gov]
An infection can cause abdominal pain, jaundice, weakness, loss of appetite, diarrhea, itching and skin rash. The only drug officially registered in Russia for the treatment of opisthorchiasis is praziquantel. [isrctn.com]
- Hepatomegaly
Moreover, symptomatic infections due to O. felineus can last a few weeks and then the signs and symptoms disappear, but the worms survive in the bile ducts for years causing hepatobiliary diseases including hepatomegaly, cholangitis, fibrosis of the periportal [ncbi.nlm.nih.gov]
With infections of longer duration, the symptoms can be more severe, and hepatomegaly and malnutrition may be present. In rare cases, cholangitis, cholecystitis, and chlolangiocarcinoma may develop. [cdc.gov]
Skin
- Skin Rash
Symptoms of infection include fever, general malaise, skin rash, and gastrointestinal disturbances. Severe anemia and liver damage may also incapacitate the infected person for 1-2 months. [wikidoc.org]
An infection can cause abdominal pain, jaundice, weakness, loss of appetite, diarrhea, itching and skin rash. The only drug officially registered in Russia for the treatment of opisthorchiasis is praziquantel. [isrctn.com]
- Ulcer
Trichuris suis eggs versus placebo for induction of remission in ulcerative colitis Trichuris suis eggs versus placebo for induction of remission in ulcerative colitis Patient or population: induction of remission in ulcerative colitis Settings: Outpatient [cochranelibrary.com]
Background:The aetiology and pathological mechanisms of mucosal damage in ulcerative colitis (UC)remain areas of controversy. [kundoc.com]
The patient suffered from a series of complications: right-side serofibrinous pleuritis, acute gastric ulcers, and multiple necrosis in the liver. [ajtmh.org]
- Eczema
Atopic symptoms in the past year (flexural eczema and/or rhinoconjunctivitis) were reported in 12.4% of the children. SPT was positively related to flexural eczema and rhinoconjunctivitis, but not to wheezing. [onlinelibrary.wiley.com]
Psychiatrical
- Suggestibility
Results of performed analysis reflect the actual epidemiological situation in opisthorchiasis focus and suggest an association of this disease with bile duct cancer. © The Author 2015. [ncbi.nlm.nih.gov]
Our findings suggest that levels of co-stimulatory molecules expression on DC are important in immune response balancing and polarization. [erj.ersjournals.com]
The similarity between the diseases caused by O. felineus and other liver flukes, O. viverrini and Clonorchis sinensis, in clinical manifestations and course suggests that the scenarios of their development and… Figures and Tables from this paper 83 Citations [semanticscholar.org]
Opisthorchis felineus is a liver fluke that primarily infects cats, as its name suggests, but it is also sometimes called the "Siberian Liver Fluke" because of its prevalence in Russia. [dailyparasite.blogspot.com]
Neurologic
- Neglect
Russia. 5 Department of Parasitology. 6 Department of Pathology. 7 Tropical Diseases Research Laboratory, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. 8 Department of Microbiology, Immunology & Tropical Medicine, Research Center for Neglected [ncbi.nlm.nih.gov]
PLoS Neglected Tropical Diseases, 14 (6). e0008421. [edoc.unibas.ch]
Show more… 2020-06-30 Published in: PLoS neglected tropical diseases. - 2020 Adolescent Adult Aged Aged, 80 and over Animals Bile Duct Neoplasms Bile Ducts Child Cross-Sectional Studies Female Fishes Humans Liver Male Middle Aged Morbidity Multivariate [sonar.ch]
- Asthenia
She had suffered fever, headache, muscle and abdomen pain, asthenia, and general malaise between late December and January. [ncbi.nlm.nih.gov]
Workup
Microbiology
- Fasciolopsis Buski
buski * Heterophyes heterophyes To the Editor: Opisthorchiasis comprises diverse clinical manifestations caused by infections with Opisthorchis felineus or O. [freethesaurus.com]
Product code: MSPY2142 £ 6.80 ex VAT | £ 6.80 Inc VAT Add to basket Fasciolopsis buski, ova w.m. prepared microscope slide. [inds.co.uk]
Biopsy
- Hepatocellular Carcinoma
Key words: Cancer / Carcinogenic / Carcinogenesis / Carcinoma / Cell transition / Cercaria / Cholangiocellular carcinoma / Clonorchis / Cyprinidae / Epidemiology / Fish / Helminthiasis / Hepatocellular carcinoma / Liver flukes / Malignancy / Opisthorchiasis [4open-sciences.org]
Treatment
Thus, this combination chemotherapy revealed no benefits over praziquantel monotherapy in the treatment of opisthorchiasis felinea. [ncbi.nlm.nih.gov]
Egg reduction rate against Opisthorchis felineus infection assessed post-treatment assessed pre-treatment to post-treatment on 18-25 days of the follow-up. [isrctn.com]
Patient outcome is dependent on early detection and treatment. Human cases of opisthorchiasis may affect the liver, pancreas, and gall bladder. [wikidoc.org]
After treatment, no eggs were detected in the woman’s feces. She reported that 33 days before seeking treatment, she had eaten marinated tench filets at a restaurant. [doi.org]
Prognosis
However, the questions connected with epidemiology of these trematode infections, their clinical characteristics, prognosis and therapy remain open. [ncbi.nlm.nih.gov]
Etiology
Twelve participants had had symptoms of unknown etiology in late December of 2009 and early January of 2010 (Table 1). [ncbi.nlm.nih.gov]
The etiologic agents for opisthorchiasis are O. viverrini and O. felineus. O. viverrini adult flukes are approximately 5 mm to 10 mm by 1 mm to 2 mm and O. felineus are roughly 7 mm to 12 mm by 2 mm to 3 mm long (1). [austincc.edu]
Epidemiology
Results of performed analysis reflect the actual epidemiological situation in opisthorchiasis focus and suggest an association of this disease with bile duct cancer. © The Author 2015. [ncbi.nlm.nih.gov]
Studies on the carcinogenic potential of this liver fluke and the epidemiology of cholangiocarcinoma in the Russian Federation have started in earnest quite recently. [4open-sciences.org]
@article{Pakharukova2016TheLF, title={The liver fluke Opisthorchis felineus: biology, epidemiology and carcinogenic potential.}, author={Mariya Y Pakharukova and Viatcheslav A. [semanticscholar.org]
Prevention
For this reason the timely detection of Opisthorchiasis is important for Cholangiocarcinoma prevention. [ncbi.nlm.nih.gov]
He joined the Centers for Disease Control and Prevention (CDC) in 1993, first as a guest researcher and then as a senior staff fellow. [books.google.es]
Thus, ABC drug transporters in the liver fluke O. felineus are functionally active, indicating that ABC drug transporters are likely to be molecular targets for a combination therapy aimed at prevention of a xenobiotic removal from helminth tissues and [research.nsu.ru]