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Optic Papillitis


Presentation

  • Special Notes boxes present ICD-10 features that affect your understanding of the terminology presented. Root operation tables illustrate the root operations in PCS and their associated suffixes.[books.google.com]
  • Because increased intracranial pressure can cause both papilledema and a sixth (abducens) nerve palsy, papilledema can be differentiated from papillitis if esotropia and loss of abduction are also present.[en.wikipedia.org]
  • Improve your interpretation of presenting symptoms with 39 new topics in the Differential Diagnosis section, and optimize patient care with 12 new tables in the Clinical Practice Guidelines section.[books.google.com]
  • Case 2 A 27 year old man presented with a 4 months history of generalised headache. Five days prior to presentation he awoke with left sided facial and limb weakness which improved spontaneously though incompletely over the subsequent days.[ispub.com]
  • Subacute sclerosing panencephalitis presenting as optic neuritis. Indian J Ophthalmol 1999;47:250-2 How to cite this URL: Tandon R, Khanna S, Sharma M C, Seshadri S, Menon V. Subacute sclerosing panencephalitis presenting as optic neuritis.[ijo.in]
Venous Insufficiency
  • Insufficiency (CCSVI) Completed NCT01356134 30 European Increlex (Mecasermin [rDNA Origin] Injection) Growth Forum Database - IGFD Registry Recruiting NCT00903110 Increlex 31 Quality and Diagnostic Utility of Mydriatic Fundus Plenoptic Photography Suspended[malacards.org]
Blurred Vision
  • A 30-year-old woman had blurred vision, marked optic nerve disc swelling, serous retinal detachment at the macular on optic coherence tomography, and MOG-IgG seropositivity. The patient was thought to have optic papillitis associated with MOG-IgG.[ncbi.nlm.nih.gov]
  • Therefore, the most common symptom is vision loss: you can experiment blur vision, darkened vision (as if there was less light or brightness), a part of the vision can seem to be missing (at the center or from the sides) or a permanent black spot can[icrcat.com]
  • You may notice some of these symptoms: Pain when you move your eyes Blurred vision Loss of color vision Trouble seeing to the side A hole in the center of your vision Blindness in rare cases Headache -- a dull ache behind your eyes Adults usually get[webmd.com]
  • The reduced vision can range from a small patch of blurred vision to near total blindness. The blurriness can be worsened by exercise ( Uhthoff's phenomenon ) or heat.[vision-and-eye-health.com]
  • The majority of patients describe diffuse blurred vision, although some recognize that the blurring is predominantly central.[arabmedmag.com]
Withdrawn
  • Completed NCT00873613 Not Applicable 24 Disc Edema in Patients With Chronic Kidney Disease Withdrawn NCT00769834 25 Operative Procedures vs.[malacards.org]
Neonate-Onset
  • Completed NCT02017444 Phase 2 AZD4017 11 Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease Terminated NCT00069329 Phase 1, Phase 2 anakinra 12 Safety Study of Fluconazole in Combination With Flucytosine for the Treatment[malacards.org]
Papilledema
  • It is often an early sign of multiple sclerosis. [2] Papillitis may have the same appearance as papilledema. However, papillitis may be unilateral, whereas papilledema is almost always bilateral.[en.wikipedia.org]
  • Chronic papilledema may cause optic atrophy and visual loss. (miller et al., clinical neuro-ophthalmology, 4th ed, p175) ICD-9-CM Volume 2 Index entries containing back-references to 377.31 : Papillitis 377.31 optic 377.31[icd9data.com]
  • Unknown status NCT02410148 Not Applicable 18 Ocular Point of Care Ultrasound (POCUS) to Detect Optic Disc Swelling in Comparison to Ophthalmologic Examination Unknown status NCT02992262 Not Applicable 19 OCT Imaging of Papilledema in Pediatric Idiopathic[malacards.org]
  • Sadun AA: Optic atrophy and papilledema; in Albert MA, Jakobiek FA (eds): Principles and Practice of Ophthalmology. Philadelphia, Saunders, 1994, vol IV, pp 2534–2537.[karger.com]
Neurologic Manifestation
  • Our case highlighted the protean neurological manifestations of M. pneumoniae infection.[ncbi.nlm.nih.gov]
  • Our case highlighted the protean neurological manifestations of M . pneumoniae infection. Keywords Mycoplasma pneumoniae Central nervous system Meningitis Optic papillitis This is a preview of subscription content, log in to check access.[link.springer.com]
  • The diagnosis of SSPE was suspected clinically only after the neurologic manifestations developed and were confirmed by a brain biospy.[ijo.in]
  • It may cause neuroretinitis and occasionally acute retrobulbar neuritis, associated with other neurological manifestations, which may mimic MS (see Chapter 20).[archive.org]

Workup

  • Workup of the patient with papillitis includes lumbar puncture and cerebrospinal fluid analysis. B henselae infection can be detected by serology. MRI is the preferred imaging study.[en.wikipedia.org]
  • A complete workup including cranial imaging, lumbar puncture, and serologic evaluation in patients presenting with acute neuroretinitis is often necessary because treatments are directed toward the underlying pathogen.[lymeneteurope.org]
  • Further workup may include CSF studies of cell count, glucose, protein, VDRL and electrophoresis evaluating for oligoclonal bands.[webeye.ophth.uiowa.edu]
  • See Workup for more detail.[emedicine.medscape.com]

Treatment

  • Treatment depends on which disorder that you have. With some optic nerve disorders, you may get your vision back. With others, there is no treatment, or treatment may only prevent further vision loss.[icdlist.com]
  • Rapid treatment to reduce the inflammation, or to treat the underlying condition causing the inflammation, can salvage vision.[beltina.org]
  • Completed NCT02017444 Phase 2 AZD4017 11 Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease Terminated NCT00069329 Phase 1, Phase 2 anakinra 12 Safety Study of Fluconazole in Combination With Flucytosine for the Treatment[malacards.org]
  • CURRENT Diagnosis & Treatment: Pediatrics, 21e Chapter 16. Eye Diseases of the Optic Nerve External links [ edit ][en.wikipedia.org]
  • This book's greatest asset is the ability to illustrate that medical and surgical treatment options are actually part of a continuum in the management of disease.[books.google.com]

Prognosis

  • Optic Neuritis: Diagnosis, Treatment, and Prognosis Release Date: March 24, 2008 Introduction Optic neuritis is a term used to refer to inflammation of the optic nerve.[arabmedmag.com]
  • One trial (small and non-randomised, using a different regimen) reported improved vision with immunoglobulin treatment. [ 14 ] Prognosis Visual prognosis The prognosis for vision in ADON is usually good. [ 15 ] The Optic Neuritis Treatment Trial (ONTT[patient.info]
  • Optic neuritis in children has specific clinical features and a better prognosis than in adulthood.[journalofoptometry.org]
  • Optic neuritis in demyelinating disease has a favorable prognosis without treatment for an individual attack, but over a period of years significant visual loss is the rule since permanent damage results from recurrent attacks.[healthcentral.com]
  • Prognosis Prognosis depends upon the etiology and treatment of the bilateral optic disc edema. [2] With appropriate and prompt treatment, in most cases vision can be preserved.[eyewiki.org]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Infectious etiologies may require directed antibiotic therapy.[eyewiki.org]
  • Neuritis- painful vision loss presentation Epidemiology Age 18-40 yr Mean age 30-35 yr Incidence 6.4/ 100,000 Female (66%) Highest in higher latitudes; lower near equator Prevalence 115/100,000 Race Caucasian African americans Pathophysiology Possible Etiology[fprmed.com]
  • The most common etiology of pediatric papillitis is a preceding viral illness (parainfectious).[journal.opted.org]
  • Etiology Optic neuritis can arise in the setting of many infective and non-infective conditions: non-infective multiple sclerosis (most common) neuromyelitis optica (NMO) anti-MOG associated encephalomyelitis sarcoidosis acute disseminated encephalomyelitis[radiopaedia.org]

Epidemiology

  • Part I: epidemiology and course of disease. Am J Ophthalmol 2003;136:973–988. 2. Atmaca LS, Simsek T, Batioglu F. Clinical features and prognosis in ocular toxoplasmosis. Jpn J Ophthalmol 2004;48:386–391. 3. Biswas J, Narain S, Das D, Ganesh SK.[synapse.koreamed.org]
  • Scandinavia, United Kingdom, Canada), again, following the epidemiology of MS 3.[radiopaedia.org]
  • Epidemiology of multiple sclerosis in the pediatric population of Sardinia, Italy. Eur J Pediatr. 2015 Jul 10. [Medline]. Banwell B, Kennedy J, Sadovnick D, Arnold DL, Magalhaes S, Wambera K, et al.[emedicine.medscape.com]
  • Optic Neuritis Background Definition Inflammation & demyelinating injury of optic nerve Overview Optic nerve lesions usually produce sudden monocular visual reduction/loss Neuritis- painful vision loss presentation Epidemiology Age 18-40 yr Mean age 30[fprmed.com]
  • Sero-epidemiology of subacute sclerosing panencephalitis in Delhi. Indian J Med Res 1990;91:94-97. [ PUBMED ] 3. Saha V, John TJ, Mukundan P, Gnanamuthu C, Prabhakar S, Arjundas G, et al.[ijo.in]
Sex distribution
Age distribution

Pathophysiology

  • […] visual reduction/loss Neuritis- painful vision loss presentation Epidemiology Age 18-40 yr Mean age 30-35 yr Incidence 6.4/ 100,000 Female (66%) Highest in higher latitudes; lower near equator Prevalence 115/100,000 Race Caucasian African americans Pathophysiology[fprmed.com]
  • Hypoperfusion of the cerebral white matter in multiple sclerosis: possible mechanisms and pathophysiological significance.[journals.plos.org]
  • […] increases the risk of disc edema. [3] A history of cerebrospinal fluid shunt device places a person at risk due to a high rate of shunt malfunction over time and optic disc edema may be the presenting or only sign of shunt failure in these patients. [5] Pathophysiology[eyewiki.org]
  • Pathophysiology The pathology of ADON involves demyelination and axonal loss, probably due to an inflammatory process and a delayed hypersensitivity reaction. Recovery is due to remyelination and compensatory neuronal recruitment.[patient.info]
  • Pathophysiology Possible mechanisms of inflammation in immune-mediated optic neuritis are the cross-reaction of viral epitopes and host epitopes and the persistence of a virus in central nervous system (CNS) glial cells.[emedicine.medscape.com]

Prevention

  • Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets[books.google.com]
  • With others, there is no treatment, or treatment may only prevent further vision loss. Optic glioma (Medical Encyclopedia) Optic nerve atrophy (Medical Encyclopedia) Optic neuritis (Medical Encyclopedia) [ Read More ][icdlist.com]
  • Part of the encyclopedia is a disease dictionary including not only recommendation how to prevent each disease but also its initial symptoms, causes and useful advices about treatment for given illness.[beltina.org]
  • Conclusion: Early diagnosis and prompt treatment with penicillin is essential to prevent visual impairment in syphilitic optic neuropathy.[ispub.com]
  • […] some patients to give relief have included: salt water mouth rinses cold fluids soothing foods such as yoghurt antiseptic or local anaesthetic mouthwashes topical steroids However, the majority of sufferers have found nothing to relieve the symptoms or prevent[dermnetnz.org]

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