Abstract Case presentation: A 35-year-old woman without any known systemic disorder presented with a complaint of painful and rapidly increasing proptosis in her right eye. [pubmed.ncbi.nlm.nih.gov]

[…] in the present case. [contempclindent.org]

The sporadic form usually presents with abdominal findings. It is rare in adults, making up less than 1% of non‐Hodgkin's lymphomas. Typical age of presentation is less than 35 years. [shmabstracts.com]

Concomitant paranasal sinus involvement was present in 8 of 16 patients. [ncbi.nlm.nih.gov]

Non-African Burkitt lymphoma presenting with oral thrush and an orbital mass in a child. Arch Ophthalmol 1998; 124 :859–61. [nature.com]

• Diplopia

  Three months after the initiation of chemotherapy, strabismus and diplopia had resolved, and proptosis markedly decreased, although there was no change in her BCVA. [bmcophthalmol.biomedcentral.com]

  Four weeks later, patient presented with orbital involvement as diplopia, sixth cranial nerve palsy, and medial rectus palsy. Chemotherapy regimen according to LMB 89 protocol was started. [contempclindent.org]

  RESULTS: A 66 year old male presented to the Accident and Emergency department with a 36 hour history of diplopia on waking, left retro-orbital pain and neck ache. On admission he had evidence of partial bilateral abducens nerve palsies. [neurology.org]

  Although diplopia and ocular palsies have been previously reported in patient with BL, rarely bilateral cavernous syndrome is the initial manifestation in immunocompetent adults. [ibimapublishing.com]

  Other symptoms include double vision (diplopia), and pupillary abnormalities. The associated lid dysfunction and incomplete lid closure (lagophthalmos) or lacrimal gland dysfunction can result in exposure keratopathy, keratitis, and ocular pain. [skullbaseinstitute.com]

• Strabismus

  Three months after the initiation of chemotherapy, strabismus and diplopia had resolved, and proptosis markedly decreased, although there was no change in her BCVA. [bmcophthalmol.biomedcentral.com]

  […] see also Systemic Diseases) Trauma (Injury), Toxic Keratopathies, Radiation Tumors, Neoplasma Glaucomas, Ocular Hypertension Hypertensive Retinopathy Iris and Ciliary Body Lacrimal System Lens Lids Neuro-Ophthalmology Optic Nerve Orbit Retina Sclera Strabismus [atlasophthalmology.net]

• Unilateral Proptosis

  Symptoms Orbital tumors typically present with early unilateral proptosis of the globe and may adversely affect visual and extraocular muscle function. Other symptoms include double vision (diplopia), and pupillary abnormalities. [skullbaseinstitute.com]

  This report describes the case of a 14-year-old boy who presented with rapidly progressive unilateral proptosis which was found to be round cell tumor on histopathology. [ccij-online.org]

• Eye Pain

  pain, eyelid swelling, chemosis, altered visual acuity, proptosis, ptosis, diplopia, restricted ocular motility, and afferent papillary defect. [13], [21] The orbital involvement in our case presented initially as diplopia of the right eye followed by [contempclindent.org]

The large number of patients with central nervous system involvement in our review of the literature supports the role of lumbar puncture and neuroimaging in the workup of all patients with orbital Burkitt lymphoma. [ncbi.nlm.nih.gov]

Further systemic workup was performed for BL. Cytogenetic analysis did not show aneusomy or Myc rearrangement in 200 of 200 interphase nuclei. [karger.com]

Expedite the staging workup. A diagnosis can sometimes be made by bone marrow aspiration and biopsy if the marrow is involved. If the marrow is not involved, diagnosis will require sampling lymph nodes or the involved extranodal site. [emedicine.medscape.com]

Imaging procedure such as computed tomography and magnetic resonance imaging can help determine the extent of the primary disease, and a total body disease workup should include positron emission tomography and evaluation of the bone marrow and cerebrospinal [czytelniamedyczna.pl]

[…] for Low Back Pain 234 IntraDiscalElectroTherapy IDET 235 Medial Branch RadioFrequency Lesionning 236 Minimally Invasive Treatments for Leg Pain 237 Percutaneous Epidural Neuroplasty Racz Procedure and Epiduroscopy 238 Spinal Cord Stimulation 239 Intrathecal [books.google.com]

For more information about the treatment options described here, see the Treatment Options section. [cancer.net]

A heterogenous thickening seen in the right maxillary sinus (three months after treatment) Figure 4. A mild thickness in the right maxillary sinus (six months after treatment) Figure 5. [pubs.sciepub.com]

Management and treatment Management should be carried out in a specialist oncology/hematology centers. Treatment is with a few months of intensive chemotherapy. [orpha.net]

The patient after 5 days of treatment. [healio.com]

Treatment and prognosis Prognosis depends on stage as well as several other factors such as age, serological markers (ESR), presence of B symptoms, and histological tumor subtype: nodular lymphocyte predominant: best prognosis lymphocyte depleted: worse [radiopaedia.org]

This differential diagnosis is important because confirmation leads to a change in the vital prognosis of the patient. [pubmed.ncbi.nlm.nih.gov]

Involvement of the central nervous system and bone marrow is indicative of a poor prognosis. [healio.com]

The prognosis of most of sBL with orbital involvement is poor and only one patient out of eight, including the present case was alive at 5 years posttreatment. [13], [21] The combination of neuro-orbital involvement resulted in extremely poor prognosis [contempclindent.org]

Both hodgkin and non-hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer. [icd10data.com]

Etiology In most cases Burkitt lymphoma is associated with a specific translocation t(8;14)(q24;q32) that juxtaposes the MYC/c-Myc gene (8q24) next to the heavy chain immunoglobulin gene (14q32). [orpha.net]

Diagnosis Evaluation of a patient with a presumed orbital mass begins with a thorough ophthalmic and medical history including history of allergies, sinus infections, recent trauma to rule out all non-neoplastic sinonasal etiologies for the disease process.It [skullbaseinstitute.com]

More rarely, an infectious etiology should also be considered. [djo.harvard.edu]

Burkitt's lymphoma in Africa, a review of the epidemiology and etiology. Afr Health Sci 2007;7:166-75. 4. Patton LL, McMillan CW, Webster WP. American Burkitt's lymphoma: A 10-year review and case study. [contempclindent.org]

In endemic areas, there seems to be a correlation with the geographic distribution of endemic malaria. [22, 23] (See Etiology and Pathophysiology.) Although no racial predilection is reported, there is a sex and age predilection. [emedicine.medscape.com]

In: Cancer Epidemiology and Prevention. M Schottenfeld, JF Fraumeni, eds, WB Saunders, Philadelphia 1982:754-78. National Cancer Institute. Surveillance epidemiology end results. Incidence and mortality data: 1973-1977. Monograph 57. U.S. [cdc.gov]

[…] repository Jump to navigation Jump to search Radiology : Ultrasound · X-ray · Computed tomography · Magnetic resonance · Positron emission tomography · Bone scintigraphy | Anatomical pathology : Gross pathology · Histopathology | Other : Endoscopy · Epidemiology [commons.wikimedia.org]

 Introduction Definition Epidemiology Aetiology Clinical Features Investigations Staging Treatment Prognosis 3.  Lymphomas are malignant proliferation of the lymphoid tissue2 broad classification: Hodgkin’s d’se and Non-Hodgkin’s lymphoma [slideshare.net]

Wright GH (1967) The epidemiology of Burkitt’s tumor. Cancer Res 27, pt 1: 2424–2438 PubMed Google Scholar 12. Ziegler L (1977) Treatment results of 54 American patients with Burkitt’s lymphoma are similar to the African experience. [link.springer.com]

Burkitt lymphoma has provided a model for the understanding of the epidemiology, the molecular abnormalities that induce tumours and the treatment of other lymphomas. [ecancer.org]

[…] and pathophysiologic mechanisms leading to the development of Burkitt lymphoma are not known. [emedicine.medscape.com]

To prevent tumor lysis, some groups prefer to give an initial low dose "cytoreductive" treatment followed by more intensive chemotherapy.5 The prognosis for this disease is directly related to tumor burden. [healio.com]

Lymphoma cause, prevention and treatment of lymphoma with herbs, vitamins, supplements, and natural diet options January 2 2016 by Ray Sahelian, M.D. [raysahelian.com]

Radiotherapy,BL is a radio-sensitive tumour but b’se of it’s rapid growth, radiotherapy is ineffectiveTumour regrows btn @ day’s therapyProphylactic craniospinal irradiation achieved no results in preventing or delaying CNS relapse 28.  ANY QUESTIONS [slideshare.net]

In: Cancer Epidemiology and Prevention. M Schottenfeld, JF Fraumeni, eds, WB Saunders, Philadelphia 1982:754-78. National Cancer Institute. Surveillance epidemiology end results. Incidence and mortality data: 1973-1977. Monograph 57. U.S. [cdc.gov]