Presentation
[…] in the present case. [contempclindent.org]
Abstract Case presentation: A 35-year-old woman without any known systemic disorder presented with a complaint of painful and rapidly increasing proptosis in her right eye. [pubmed.ncbi.nlm.nih.gov]
Concomitant paranasal sinus involvement was present in 8 of 16 patients. [ncbi.nlm.nih.gov]
We reviewed a total of 11 cases of lymphoma presenting with pituitary dysfunction published from 1998 to 2013 including the present case. [edmcasereports.com]
The sporadic form usually presents with abdominal findings. It is rare in adults, making up less than 1% of non‐Hodgkin's lymphomas. Typical age of presentation is less than 35 years. [shmabstracts.com]
Entire Body System
- Pain
232 Minimally Invasive Treatments for Low Back Pain 234 IntraDiscalElectroTherapy IDET 235 Medial Branch RadioFrequency Lesionning 236 Minimally Invasive Treatments for Leg Pain 237 Percutaneous Epidural Neuroplasty Racz Procedure and Epiduroscopy 238 [books.google.com]
Secondary deposits in the spine cause intractable back pain. Abdominal pain Patients with extranodal involvement can have intra-abdominal mass. [explainmedicine.com]
Conclusion In patients presenting with painful proptosis and vision loss, a diagnosis of BL should be considered. [bmcophthalmol.biomedcentral.com]
Case Presentation: A 63‐year‐old female with past medical history of meningioma was admitted with one‐week history of swelling, watering, painful movements and vision loss in right eye. [shmabstracts.com]
The other common associated presenting symptoms were painful ophthalmoplegia, cranial nerve palsies and constitutional symptoms. [edmcasereports.com]
- Swelling
Figure 1: Extraoral photograph showing mildly diffused swelling on the right side maxillary region Click here to view Figure 2: Intraoral photograph of showing diffused swelling on the right side maxillary teeth bearing area extending from central incisor [contempclindent.org]
The most common signs and symptoms associated with lymphoma include swelling of the lymph nodes in the neck, armpit, or groin; fever; unexplained weight loss; night sweats; chills; fatigue; itching; and abdominal pain/swelling. [fortherecordmag.com]
Burkitt's lymphoma ( A ) There is marked swelling of the right side of the face, involving both the maxilla and the mandible. [isradiology.org]
The most common presentation is a swelling of the affected jaw / bone as well as rapidly enlarging, non-tender lymph nodes in the neck / jaw. [worktheworld.com]
Coughing or sore throat Night sweats Fever or recurring infection Painless swelling of the lymph nodes in the neck, chest, abdomen, groin, or underarm Trouble breathing or wheezing Trouble swallowing Unexplained high temperature/fever Unexplained weight [redfeatherscribe.wordpress.com]
- Lymphadenopathy
All patients had generalized lymphadenopathy, and 3 had splenomegaly of uncertain duration. Detailed virology and immunology studies are in progress. [cdc.gov]
Typical presentation is with painless lymphadenopathy. Systemic symptoms (B symptoms) such as night sweats and weight loss may be present. [radiopaedia.org]
(Image 1) CT scan of abdomen and pelvis showed ascites, multiple splenic lesions, retroperitoneal lymphadenopathy and a mass along the left external iliac chain. [shmabstracts.com]
ENT examination revealed edema and erythema of the right cheek, neck lymphadenopathy with no other abnormalities. [czytelniamedyczna.pl]
Imaging findings on US include asymmetric bowel wall thickening, solid hypoechoic mass lesion, ascites, or lymphadenopathies. [ncbi.nlm.nih.gov]
- Surgical Procedure
Caldera DL, Nussbaum SR. et aL Multifactorial index of cardiac risk in noncardiac surgical procedures. Página 106 - Tarhan S, Moffitt EA, Taylor WF, et al. Myocardial infarction after general anesthesia. JAMA 1972;220:1451. [books.google.es]
Procedures and Postoperative Findings Systemic Diseases (see also Systemic Diseases) Trauma (Injury), Toxic Keratopathies, Radiation Tumors, Neoplasma Glaucomas, Ocular Hypertension Hypertensive Retinopathy Iris and Ciliary Body Lacrimal System Lens [atlasophthalmology.net]
Gastrointestinal
- Nausea
Intra-cranial lesions cause early morning headache, nausea and vomiting. [9] Risk factors of HIV Patients who had unsafe sex with multiple sexual partners are at risk of acquiring HIV. [explainmedicine.com]
She also had generalized weakness, 15 lb weight loss, anorexia, nausea, crampy abdominal pain and diarrhea. Her right eye was proptotic with visual acuity to hand movement only, intraocular pressure of 72mmHg and severly restricted range of motion. [shmabstracts.com]
The most frequent clinical signs are abdominal pain, nausea, an alteration of general state and/or the appearance of lymph nodes and tumors. [orpha.net]
Some of the treatment options may result in after-effects such as nausea, vomiting, irritation or soreness of the skin from radiation, hair loss, risk of infection, fatigue, bruising and bleeding or diarrhoea. [redfeatherscribe.wordpress.com]
However, depending on where it has spread it can also affect the bowel and the lymph nodes in the tummy (abdomen), causing symptoms such as pain, feeling sick (nausea) and diarrhoea. [worktheworld.com]
- Vomiting
Symptoms of intestinal obstruction (nausea, vomiting, colicky abdominal pain and absolute constipation), intussusception (severe colicky abdominal pain, vomiting, red currant jelly stools and drawing up legs during crying) and appendicitis (periumbilical [explainmedicine.com]
Clinically, the patient presented severe abdominal pain and vomiting. Imaging findings were suggestive of inflammatory involvement of the pancreas, heading treatment towards this hypothesis. [revistas.usp.br]
Some of the treatment options may result in after-effects such as nausea, vomiting, irritation or soreness of the skin from radiation, hair loss, risk of infection, fatigue, bruising and bleeding or diarrhoea. [redfeatherscribe.wordpress.com]
Abdominal BL may present with a palpable mass, abdominal pain, nausea and vomiting, constipation, melena, weight loss, and/or jaundice. BL can also serve as the lead point for an intussusception and can mimic appendicitis. [clinicaladvisor.com]
If the tumor is in the abdomen, it often leads to nausea, vomiting, and pain, due to the intestinal obstruction. [czytelniamedyczna.pl]
Musculoskeletal
- Osteoporosis
[…] syndrome Low phospholipid-associated cholelithiasis Lowry-MacLean syndrome Lowry syndrome Lowry-Wood syndrome Lowry-Yong syndrome LPA LPAC LPD LPG LPI LPL deficiency LPP LPP LP pemphigoides LP pigmentosa LP pigmentosus LQT7 LQT8 LRP5-related primary osteoporosis [orpha.net]
Eyes
- Diplopia
Three months after the initiation of chemotherapy, strabismus and diplopia had resolved, and proptosis markedly decreased, although there was no change in her BCVA. [bmcophthalmol.biomedcentral.com]
Four weeks later, patient presented with orbital involvement as diplopia, sixth cranial nerve palsy, and medial rectus palsy. Chemotherapy regimen according to LMB 89 protocol was started. [contempclindent.org]
RESULTS: A 66 year old male presented to the Accident and Emergency department with a 36 hour history of diplopia on waking, left retro-orbital pain and neck ache. On admission he had evidence of partial bilateral abducens nerve palsies. [neurology.org]
Although diplopia and ocular palsies have been previously reported in patient with BL, rarely bilateral cavernous syndrome is the initial manifestation in immunocompetent adults. [ibimapublishing.com]
Other symptoms include double vision (diplopia), and pupillary abnormalities. The associated lid dysfunction and incomplete lid closure (lagophthalmos) or lacrimal gland dysfunction can result in exposure keratopathy, keratitis, and ocular pain. [skullbaseinstitute.com]
- Strabismus
Three months after the initiation of chemotherapy, strabismus and diplopia had resolved, and proptosis markedly decreased, although there was no change in her BCVA. [bmcophthalmol.biomedcentral.com]
[…] see also Systemic Diseases) Trauma (Injury), Toxic Keratopathies, Radiation Tumors, Neoplasma Glaucomas, Ocular Hypertension Hypertensive Retinopathy Iris and Ciliary Body Lacrimal System Lens Lids Neuro-Ophthalmology Optic Nerve Orbit Retina Sclera Strabismus [atlasophthalmology.net]
- Unilateral Proptosis
Symptoms Orbital tumors typically present with early unilateral proptosis of the globe and may adversely affect visual and extraocular muscle function. Other symptoms include double vision (diplopia), and pupillary abnormalities. [skullbaseinstitute.com]
This report describes the case of a 14-year-old boy who presented with rapidly progressive unilateral proptosis which was found to be round cell tumor on histopathology. [ccij-online.org]
- Eye Pain
pain, eyelid swelling, chemosis, altered visual acuity, proptosis, ptosis, diplopia, restricted ocular motility, and afferent papillary defect. [13], [21] The orbital involvement in our case presented initially as diplopia of the right eye followed by [contempclindent.org]
Neurologic
- Confusion
This rare form of lymphoma may be confused with an epithelial tumor with light microscopy and even with electron microscopy ( 2 ). Cutaneous T-cell lymphoma (mycosis fungoides) can also affect the orbit ( 3 ). [entokey.com]
Workup
The large number of patients with central nervous system involvement in our review of the literature supports the role of lumbar puncture and neuroimaging in the workup of all patients with orbital Burkitt lymphoma. [ncbi.nlm.nih.gov]
Further systemic workup was performed for BL. Cytogenetic analysis did not show aneusomy or Myc rearrangement in 200 of 200 interphase nuclei. [karger.com]
Expedite the staging workup. A diagnosis can sometimes be made by bone marrow aspiration and biopsy if the marrow is involved. If the marrow is not involved, diagnosis will require sampling lymph nodes or the involved extranodal site. [emedicine.medscape.com]
Imaging procedure such as computed tomography and magnetic resonance imaging can help determine the extent of the primary disease, and a total body disease workup should include positron emission tomography and evaluation of the bone marrow and cerebrospinal [czytelniamedyczna.pl]
Treatment
[…] for Low Back Pain 234 IntraDiscalElectroTherapy IDET 235 Medial Branch RadioFrequency Lesionning 236 Minimally Invasive Treatments for Leg Pain 237 Percutaneous Epidural Neuroplasty Racz Procedure and Epiduroscopy 238 Spinal Cord Stimulation 239 Intrathecal [books.google.com]
For more information about the treatment options described here, see the Treatment Options section. [cancer.net]
Management and treatment Management should be carried out in a specialist oncology/hematology centers. Treatment is with a few months of intensive chemotherapy. [orpha.net]
Although just as prevalent as in the UK, resources are dramatically reduced and it is thought that only 5% of sufferers have access to treatment facilities. [worktheworld.com]
The patient after 5 days of treatment. [healio.com]
Prognosis
Treatment and prognosis Prognosis depends on stage as well as several other factors such as age, serological markers (ESR), presence of B symptoms, and histological tumor subtype: nodular lymphocyte predominant: best prognosis lymphocyte depleted: worse [radiopaedia.org]
Involvement of the central nervous system and bone marrow is indicative of a poor prognosis. [healio.com]
The prognosis of most of sBL with orbital involvement is poor and only one patient out of eight, including the present case was alive at 5 years posttreatment. [13], [21] The combination of neuro-orbital involvement resulted in extremely poor prognosis [contempclindent.org]
Both hodgkin and non-hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer. [icd10data.com]
Prognosis remains guarded, with significant mortality within 1 year of presentation. [ncbi.nlm.nih.gov]
Etiology
Etiology In most cases Burkitt lymphoma is associated with a specific translocation t(8;14)(q24;q32) that juxtaposes the MYC/c-Myc gene (8q24) next to the heavy chain immunoglobulin gene (14q32). [orpha.net]
Diagnosis Evaluation of a patient with a presumed orbital mass begins with a thorough ophthalmic and medical history including history of allergies, sinus infections, recent trauma to rule out all non-neoplastic sinonasal etiologies for the disease process.It [skullbaseinstitute.com]
More rarely, an infectious etiology should also be considered. [djo.harvard.edu]
Burkitt's lymphoma in Africa, a review of the epidemiology and etiology. Afr Health Sci 2007;7:166-75. 4. Patton LL, McMillan CW, Webster WP. American Burkitt's lymphoma: A 10-year review and case study. [contempclindent.org]
In endemic areas, there seems to be a correlation with the geographic distribution of endemic malaria. [22, 23] (See Etiology and Pathophysiology.) Although no racial predilection is reported, there is a sex and age predilection. [emedicine.medscape.com]
Epidemiology
In: Cancer Epidemiology and Prevention. M Schottenfeld, JF Fraumeni, eds, WB Saunders, Philadelphia 1982:754-78. National Cancer Institute. Surveillance epidemiology end results. Incidence and mortality data: 1973-1977. Monograph 57. U.S. [cdc.gov]
[…] repository Jump to navigation Jump to search Radiology : Ultrasound · X-ray · Computed tomography · Magnetic resonance · Positron emission tomography · Bone scintigraphy | Anatomical pathology : Gross pathology · Histopathology | Other : Endoscopy · Epidemiology [commons.wikimedia.org]
Introduction Definition Epidemiology Aetiology Clinical Features Investigations Staging Treatment Prognosis 3. Lymphomas are malignant proliferation of the lymphoid tissue2 broad classification: Hodgkin’s d’se and Non-Hodgkin’s lymphoma [slideshare.net]
Burkitt lymphoma has provided a model for the understanding of the epidemiology, the molecular abnormalities that induce tumours and the treatment of other lymphomas. [ecancer.org]
Wright GH (1967) The epidemiology of Burkitt’s tumor. Cancer Res 27, pt 1: 2424–2438 PubMed Google Scholar 12. Ziegler L (1977) Treatment results of 54 American patients with Burkitt’s lymphoma are similar to the African experience. [link.springer.com]
Pathophysiology
[…] and pathophysiologic mechanisms leading to the development of Burkitt lymphoma are not known. [emedicine.medscape.com]
Prevention
To prevent tumor lysis, some groups prefer to give an initial low dose "cytoreductive" treatment followed by more intensive chemotherapy.5 The prognosis for this disease is directly related to tumor burden. [healio.com]
Lymphoma cause, prevention and treatment of lymphoma with herbs, vitamins, supplements, and natural diet options January 2 2016 by Ray Sahelian, M.D. [raysahelian.com]
Radiotherapy,BL is a radio-sensitive tumour but b’se of it’s rapid growth, radiotherapy is ineffectiveTumour regrows btn @ day’s therapyProphylactic craniospinal irradiation achieved no results in preventing or delaying CNS relapse 28. ANY QUESTIONS [slideshare.net]
In: Cancer Epidemiology and Prevention. M Schottenfeld, JF Fraumeni, eds, WB Saunders, Philadelphia 1982:754-78. National Cancer Institute. Surveillance epidemiology end results. Incidence and mortality data: 1973-1977. Monograph 57. U.S. [cdc.gov]