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Orbital Neoplasm


Presentation

  • We report a fourth case of angioleiomyoma of the orbit with the longest duration of presentation of 20 years. KEYWORDS: Angioleiomyoma; neoplasm; orbit[ncbi.nlm.nih.gov]
  • Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use.[turkiyeklinikleri.com]
  • 抄録 A 66-year-old female presented with spontaneous intraorbital hematoma manifesting as left exophthalmos after left eye discomfort persisting for 5 months. She had no history of head injury.[jstage.jst.go.jp]
  • Their clinical presentation extends across a wide spectrum and differs based on the degree of pathologic involvement.[benthamopen.com]
  • It is the second most common malignant tumour of the lacrimal gland and presents as a painless mass with or without new increase in size.[eyeplastics.com]
Falling
  • Voute Springer Science & Business Media, ٠٦‏/١٢‏/٢٠١٢ - 317 من الصفحات With the fall in mortality from infectious diseases, the impact of childhood cancer in the Western World has increased to become the second commonest cause of death in the age group[books.google.com]
Nausea
  • […] recent ocular surgery, pertinent medical conditions, medications currently used, as well as the presence of diabetes mellitus and the immune status of the patient.Specific questions regarding any change in mental status, pain with neck movement, or nausea[eyewiki.aao.org]
Diplopia
  • However, there is pain, numbness, diplopia and visual disturbance and a circumscribed lacrimal gland mass with blurred margins infiltrating into bone on CT scan. Treatment is surgical.[eyeplastics.com]
  • […] an older patient with mild proptosis and diplopia and no systemic thyroid signs or symptoms, the possibility of a metastatic orbital tumour should be considered in the differential diagnosis.[bjo.bmj.com]
  • Symptoms Most patients with orbital tumors notice a bulging of the eyeball or double vision (diplopia). Infections, inflammations and certain orbital cancers can also cause pain.[eyecancer.com]
  • Pain, diplopia, and vision loss may also be present. The diagnosis of orbital tumors is suspected based on the history, examination, and neuroimaging (CT, MRI, or both), but confirmation often ultimately requires a biopsy.[merckmanuals.com]
  • Idiopathic Inflammatory Pseudotumor (Orbital Pseudotumor) Orbital pseudotumor is an idiopathic orbital inflammatory process that typically presents clinically with an acute onset of pain, swelling, ophthalmoplegia, diplopia and proptosis. 1,2 Clinical[jaocr.org]
Strabismus
  • The initial presenting features were orbital mass (case 1), strabismus (case 2), and conjunctival mass with orbital extension (cases 3 and 4). Each patient vaguely recalled previous uncomplicated retinal detachment surgery 12 to 20 years earlier.[journals.lww.com]
  • Strabismus is the second major presenting sign of retinoblastoma. In contrast to leukocoria, tumors presenting with strabismus as their initial sign are associated with a higher survival rate and a higher chance of salvage of the globe.[clinicalgate.com]
  • Retinoblastoma - Strabismus (crossed eyes), a whitish or yellowish glow through the pupil, decreasing/loss of vision, sometimes the eye may be red and painful. Retinoblastoma can occur in one or both eyes.[en.wikipedia.org]
  • The ocular data included the affected orbit, laterality, symptoms (visual problem, red or swelling, proptosis, diplopia, palpable mass), signs (the best corrected vision, proptosis, ocular motility deficit, strabismus).[journals.plos.org]
  • Am J Ophthalmol 80:1024–1027 PubMed Google Scholar Elston J (1997) Concomitant strabismus. In: Taylor D (ed) Pediatric ophthalmology, 2nd edn.[link.springer.com]
Unilateral Proptosis
  • Symptoms Orbital tumors typically present with early unilateral proptosis of the globe and may adversely affect visual and extraocular muscle function. Other symptoms include double vision (diplopia), and pupillary abnormalities.[skullbaseinstitute.com]
  • Vision may be blurred. [ 4 ] Look for a (usually unilateral) proptosis, severe conjunctival oedema (chemosis) and limited eye movement caused by a combination of cranial nerve palsy and physical limitation of movement.[patient.info]
  • An aching discomfort, typically associated with unilateral proptosis, is an important part of the clinical presentation.[aao.org]
  • Infrequently, they may arise deeper in the orbit and cause unilateral proptosis [Figure - 7]. CT or MRI shows a well-circumscribed cystic lesion which may contain fat or foci of calcification and may have slight enhancement in its wall.[ijo.in]
Headache
  • With the advent of easy craniofacial imaging—commonly used during the investigation of head trauma, chronic headache, vascular disease, or sensorineural hearing loss—there has been a marked increase in the discovery of incidental orbital pathology.[healio.com]
  • These lesions present to the ophthalmologist with proptosis, palpable orbital masses, gaze restriction, and headache associated with chronic sinusitis and upper respiratory tract infections.[aao.org]
  • She denied any vision changes, ocular pain, pain with eye movement, or headaches. A complete review of systems was negative.[webeye.ophth.uiowa.edu]
  • Patient history should also include the presence of headache, orbital pain, double vision, progression of symptoms, recent upper respiratory symptoms (e.g. nasal discharge or stuffiness), pain over sinuses, fever, lethargy, recent periocular trauma or[eyewiki.aao.org]

Workup

  • Often, these lesions are detected on imaging inadvertently during a workup for another reason (Benatiya Andaloussi et al 2006). Osteoid osteomas generally occur in the frontal and ethmoid bones (Sires et al 1999).[webeye.ophth.uiowa.edu]
  • Choroidal Osteoma Typically calcification in the posterior globe (No image available) Benign tumors, but excluding melanoma important in the workup. Typically present in young women.[radcharts.org]

Treatment

  • However clinical conditions frequently limit the possibilities for satisfactory treatment.[benthamopen.com]
  • الصفحة 233 - A detailed treatment of these topics is beyond the scope of this chapter and the reader is referred to the references listed at the end of the chapter. 4.7.1 Brief History of Birdcage Coils 0l ¿ ¿ (a) (b) 0,, (c) rIrTrrIffl 1111 111111 ¿[books.google.com]
  • CT scan and MRI: Treatment of orbital neoplasm: 1. If slow growing and localized: a. Surgical removal, retaining of eye wherever possible 2. If rapidly growing primary or secondary malignant tumor: a.[healthdiseaseblog.com]

Prognosis

  • Although they don’t pose a threat to life prognosis, they can cause other problems such as vision loss and displacement of the globe.[willseye.org]
  • Three, did any clinical factors correlate with prognosis in this patient cohort? METHODS Retrospective analysis of patients with orbital metastases managed in an ocular oncology unit.[bjo.bmj.com]
  • Trilateral tumors usually present months after the initial discovery of the ocular lesions and have an associated dismal prognosis.[clinicalgate.com]
  • Prognosis Surgical removal is curative for many orbital tumors and the cosmetic results can be excellent. The outcome and prognosis ultimately depends on the pathological diagnosis.[skullbaseinstitute.com]
  • Prognosis is very poor. Metastases : In children the orbit may be the site of secondary deposits from neuroblastoma or acute leukaemia.[patient.info]

Etiology

  • Evaluation of the etiology of ocular globe atrophy or loss Braz Dent J 2005; 16(3): 243-6., 20 Mattos BSC, Montagna MC, Fernandes CS, Sabóia ACL.[benthamopen.com]
  • Diagnosis Evaluation of a patient with a presumed orbital mass begins with a thorough ophthalmic and medical history including history of allergies, sinus infections, recent trauma to rule out all non-neoplastic sinonasal etiologies for the disease process.It[skullbaseinstitute.com]
  • An osteoid osteoma is a benign skeletal neoplasm of unknown etiology that is composed of osteoid and woven bones. Osteoid osteomas can occur in any bone, but in approximately two thirds of patients, the appendicular skeleton is involved.[webeye.ophth.uiowa.edu]
  • Inflammatory pseudotumor of the orbit is a nongranulomatous inflammatory process of unknown etiology which presents clinically as painful exophthalmos.[ijo.in]
  • Disease Orbital Cellulitis (ICD-9 #376.01) Etiology Orbital cellulitis most commonly occurs when bacterial infection spreads from the paranasal sinuses, most often from the ethmoid sinus through the thin lamina papyracea of the medial orbital wall.[eyewiki.aao.org]

Epidemiology

  • An epidemiological study with a cross-sectional design was conducted, based on analysis of medical records of patients who underwent enucleation or evisceration of the eyeball assisted in the Department of Ocular Plastic and Orbit of the HRSJ from December[benthamopen.com]
  • DIAGNOSIS : Orbital osteoid osteoma EPIDEMIOLOGY Typically occur in a younger population (Greenspan 1993) Majority of cases involve appendicular skeleton, rare bony tumor of the orbit SIGNS If in the orbit, the lesion can displace structures leading to[webeye.ophth.uiowa.edu]
  • Epidemiology Frequency The top 3 pediatric orbital tumors are dermoid cysts, capillary hemangiomas, and rhabdomyosarcoma. Retinoblastoma can spread from the globe to the orbit.[emedicine.medscape.com]
  • Epidemiologic characteristics and clinical course of patients with malignant eyelid tumours in an incidence cohort in Olmsted County, Minnesota.[nature.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Orbital cellulitis most commonly occurs in the setting of an upper respiratory or sinus infection. The human upper respiratory tract is normally colonized with Strep pneumoniae and infection can occur through several mechanisms.[eyewiki.aao.org]
  • Pathophysiology Orbital tumefactions increase intraocular volume and cause a mass affect.[emedicine.medscape.com]
  • J Fr Ophthalmol 17:67–73 Google Scholar Leiba H, Glaser JS, Schatz NJ, Siatkowski RM (2000) Postpartum optic neuritis: etiology and pathophysiologic considerations.[link.springer.com]

Prevention

  • Completely revised and updated with 80 all-new chapters covering the most important information on current diagnostic, treatment, and preventive challenges facing feline practitioners today, Consultations in Feline Internal Medicine is an invaluable addition[books.google.com]
  • Based on this evidence, it is necessary to develop preventive actions in order to protect people from the adverse effects of ultraviolet radiation. RB was the second-most prevalent tumor.[benthamopen.com]
  • Eye cancer specialists usually reduce the steroid medication very slowly in order to prevent recurrence (return) of the disease.[eyecancer.com]
  • Primary prevention Identifying patients and effectively treating upper respiratory or sinus infections before they evolve into orbital cellulitis is an important aspect of preventing preseptal cellulitis from progressing to orbital cellulitis.[eyewiki.aao.org]

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