Presentation
Herein, we present the management of a liver transplantation recipient who presented with AML and comprehensively review the relevant literature. [ncbi.nlm.nih.gov]
Entire Body System
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Hypoxemia
Cardiac activity resumed, but the patient was declared brain dead on the third day of hospitalization when coma deteriorated to a shock state with refractory hypoxemia. Kidneys, heart, and liver were removed and transplanted into four patients. [ncbi.nlm.nih.gov]
Neurologic
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Altered Mental Status
Altered mental status developed in both patients and progressively worsened to deep coma within 80 days after transplantation; both patients died. [ncbi.nlm.nih.gov]
Workup
Recipient A underwent an extensive infectious workup that revealed positive E. chaffeensis DNA from polymerase chain reaction on peripheral blood. [ncbi.nlm.nih.gov]
For example, a status code of "pretransplant workup in progress" indicates the patient is interested in transplantation (step B complete). [doi.org]
Patients donating a kidney underwent a standard workup, including computed tomographic urography, blood work, urinalysis, medical history intake, and physical examination. [dx.doi.org]
Microbiology
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Babesia Microti
Babesia microti, an intraerythrocytic parasite, is tickborne in nature. In contrast to transmission by blood transfusion, which has been well documented, transmission associated with solid organ transplantation has not been reported. [ncbi.nlm.nih.gov]
Treatment
Autoimmune hemolytic anemia usually occurs within the first year and has been attributed to immunosuppressive treatment, infections, or underlying post-transplant lymphoproliferative disorder. [ncbi.nlm.nih.gov]
Prognosis
Prognosis of head and neck cancer arising in solid organ transplantation recipients is proven to have poor prognosis. [ncbi.nlm.nih.gov]
The cancer would probably return in the new organ, the doctors told De Leon, 50, a construction superintendent who cried when he learned of his prognosis. [sfgate.com]
It is however, widely accepted that the prognosis for heart failure in adults is improving and the new treatments for adult heart failure are beginning to permeate into paediatrics. [doi.org]
Etiology
The etiology of post-transplantation ARI is poorly understood, with only isolated clinical cases being reported, most imputed to drug toxicity. [ncbi.nlm.nih.gov]
What This Study Adds: This study of pediatric solid organ transplant recipients identifies an elevated risk of numerous cancer types in addition to non-Hodgkin’s lymphoma and provides evidence for a key role of Epstein-Barr virus in the etiology of most [pediatrics.aappublications.org]
In a series of 84 HCV-coinfected liver transplant recipients in Spain, 64% experienced at least 1 infection (largely non-OIs) and 43% developed severe infections, which proved fatal in 19%.(12) Infectious etiologies were bacterial in 45%, and fungal in [hivinsite.ucsf.edu]
Epidemiology
We reviewed medical, laboratory and epidemiological records at our hospital, and the literature concerning cases of organ-transmitted WNV infections and WNV screening of organ donors in Italy and worldwide. [ncbi.nlm.nih.gov]
Pathophysiology
Transplantation decision-making in aHUS has evolved over this time with expanding knowledge of pathophysiology and genetics, alongside refined plasma exchange and anticoagulation protocols and improved centre experience. [ncbi.nlm.nih.gov]
Current Status of Islet Transplantation 40.1 Introduction 40.2 The Burden of Type 1 Diabetes Mellitus 40.3 Pathophysiology of Type 1 Diabetes Mellitus 40.4 Standard Management of Patients with Type 1 Diabetes 40.5 Indications to Islet Transplantation [elsevier.com]
Prevention
Prophylaxis against bacterial, viral, and fungal infections is often used to prevent infection from common pathogens during high-risk periods. [ncbi.nlm.nih.gov]