The present paper is concerned with general pharmacology of L-ornithine L-aspartate and effects of the compound upon ammonia and carbon tetrachloride intoxications. [jstage.jst.go.jp]

<BR> The present paper is concerned with general pharmacology of L-ornithine L-aspartate and effects of the compound upon ammonia and carbon tetrachloride intoxications. [cir.nii.ac.jp]

GUARANTEE LEVELS EACH 100mL CONTAINS: L-Ornithine Aspartate 2,0 g L-Arginine Hydrochloride 7,5 g L-Citrulline 0,5 g Acetyl Methionine 1,0 g Choline hydrochloride 1,0 g Vehicle q.s. 100 mL PRESENTATION Vial containing 100mL EXTRA MAIN ADVANTAGES • Efficient [vetnil.com.br]

Adaptive evolution The adaptive evolution process is presented in Figure 1. [bmcbiotechnol.biomedcentral.com]

However, in patients with present or past alcohol use disorder, alcohol consumption is notoriously hard to approximate, since some patients tend to embellish their consumption [34]. [mdpi.com]

• Psychiatric Symptoms

  Brief Summary: Hepatic encephalopathy (HE) is a potentially reversible functional disorder of the brain with neurological and psychiatric symptoms. HE occurs in up to 70% of patients with cirrhosis at some time during the course of disease. [clinicaltrials.gov]

• Encephalopathy

  Nutritional therapy of portal-systemic encephalopathy: The branched-chain amino acid story. In (R.F. Butterworth and G. Pomier Layrargues, eds.) Hepatic Encephalopathy: Pathophysiology and Treatment, Humana Press, Clifton, N.J., p. 509–528, 1989. [link.springer.com]

  Brief Summary: Hepatic encephalopathy (HE) is a potentially reversible functional disorder of the brain with neurological and psychiatric symptoms. HE occurs in up to 70% of patients with cirrhosis at some time during the course of disease. [clinicaltrials.gov]

  Changes in the stool and serum metabolome mainly reflected pathophysiological changes of hepatic encephalopathy and identified possible therapeutic targets, such as valeric acid that is reduced in patients with hepatic encephalopathy but whose microbial [mdpi.com]

  ^Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Görtelmeyer R, Hendricks R, Heuser A, Karoff C, Malfertheiner P, Mayer D, Rösch W, Steffens JOral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled [examine.com]

  Treatment of precoma of hepatic encephalopathy. Unless otherwise indicated, patients may be given up to 4 ampoules per day. [mims.com]

• Hepatocellular Carcinoma

  Age of patient 18-70 years Exclusion Criteria: Patients who are terminally ill Acute on chronic liver failure Hepatocellular carcinoma Wilson's disease as the etiological factor of liver disease Advanced cardiac or pulmonary disease Presence of underlying [clinicaltrials.gov]

An important aim of treatment of HE is the reduction of the ammonia in the body by lowering the amount of ammonia produced and increasing its detoxification. [clinicaltrials.gov]

Treatment of hyperammonemia due to acute or chronic liver disease, e.g., liver cirrhosis, fatty liver and hepatitis. Treatment of precoma of hepatic encephalopathy. Unless otherwise indicated, patients may be given up to 4 ampoules per day. [mims.com]

Hepatic Encephalopathy: Pathophysiology and Treatment., Humana Press, Clifton, New Jersey, 1988, pp.49–77. Google Scholar Sherlock S. (1985). [link.springer.com]

USES • Acts as an antitoxic agent; • It helps the hepatic metabolism (hepatic protector); • Support in the treatment of exogenous intoxication; • In hyperproteic treatments and hyperammonemia (metabolic disease); • In non-infectious intoxication; • Hepatic [vetnil.com.br]

Varieties of treatments lowering the elevated blood level of ammonia have been reported to be effective in relieving the symptoms and improving the pathological conditions of ammonia intoxication. [jstage.jst.go.jp]

Patients with and without LOLA were comparable in age, sex, etiology and severity of cirrhosis as well as PPI and laxative use. [mdpi.com]

Age of patient 18-70 years Exclusion Criteria: Patients who are terminally ill Acute on chronic liver failure Hepatocellular carcinoma Wilson's disease as the etiological factor of liver disease Advanced cardiac or pulmonary disease Presence of underlying [clinicaltrials.gov]

Hepatic Encephalopathy: Pathophysiology and Treatment., Humana Press, Clifton, New Jersey, 1988, pp.49–77. Google Scholar Sherlock S. (1985). [link.springer.com]

Both physiologically and pathophysiologically glutamate serves as an ammonia-binding amino acid. [mims.com]

Differences in stool and serum metabolomes reflected the pathophysiology of hepatic encephalopathy and confirmed LOLA intake. In the urine metabolome, ethanol to acetic acid ratio was lower in patients treated with LOLA compared to controls. [mdpi.com]

Prevention of ammonia toxicity by amino acids concerned in the biosynthesis of urea.Nature 191:705–706. PubMed Google Scholar Salvatore, F., Cimino, F., D'Ayello-Caracciola, M., and Cittadini, D. (1964). [link.springer.com]

If liver function is substantially impaired, the infusion rate must be adjusted to individual patient in order to prevent nausea and vomiting. No data are available on the use of the drug in children. [mims.com]

L-ornithine-L-aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure. Hepatology 1999, 30, 636–640. [Google Scholar] [CrossRef] Kowalski, P.; Bieniecki, M. [mdpi.com]