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Orofacial Cleft Type 13
OFC13

Presentation

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.de]

Also, 116 (74.3%) subjects presented in infancy, 29 (18.6%) presented during childhood, and 11 (7.1%) presented in adulthood. [afrjpaedsurg.org]

A large percentage (52.5%) of the 40 patients presenting with tooth agenesis in Q1 presented tooth agenesis also in Q2. [progressinorthodontics.springeropen.com]

Age at presentation ranged from birth to 35 years (median-5 months) for the CL/P group, and birth to 29 years (median-12 months) for those with CP. The most common age of presentation was within the first month of life for both groups. [jpma.org.pk]

All patients’ files were reviewed for the following information: demographic data (age, gender), medical history (age at presentation, presenting symptoms, other medical problems), surgical history (for any operation done other than the primary repair [jpss.eu]

Workup

Before any surgical correction of clefts, all children should have a systematic clinical cardiac assessment as a part of preoperative workup, due to the highest risk of CHD among the associated abnormalities. [journals.plos.org]

Routine surgical preoperative workup was done for the subjects [who met the minimum criteria of age ≥10 weeks, weight ≥10 pounds (4.5 kg) with a hemoglobin concentration of 10 gm/dl, and free from upper respiratory tract infection] before scheduling for [afrjpaedsurg.org]

Treatment

We can help to maximize normal appearance through surgery and other treatments. [chop.edu]

and free cleft treatment available in the hospital. [afrjpaedsurg.org]

In some cases surgical intervention is required prior to the initiation of speech treatment. What contributes to the incomplete closure of lip/palate continues to be researched. [mrshc.org]

A fully integrated cleft team provides life-long interdisciplinary holistic treatment for patients born with an orofacial cleft. [karger.com]

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.de]

Prognosis

Type-specific sonographic features include: type III: may be seen as a premaxillary echogenic mass 8 Ancillary sonographic features there can be polyhydramnios if the defect is severe and impairs swallowing Treatment and prognosis The overall prognosis [radiopaedia.org]

Prognosis Both cleft lip and cleft palate are treatable birth defects. [encyclopedia.com]

Prognosis Treatment takes place over several years as the child grows and the palate and dentition develop. However, it is possible to achieve a normal appearance, and normal speech and eating habits, early in the process. [patient.info]

They further suggest that type 1 clefts are associated with a low rate of anomalies and type 2 and 3 clefts with intermediate prognosis. Type 4 and 5 clefts are universally associated with concurrent anomalies and with fatal outcome[ 26 ]. [wjgnet.com]

Prognosis of facial growth in patients with unilateral complete clefts of the lip, alveolus and palate. J Craniomaxillofac Surg. 29, 198-204 (2001). Parsons, K. J., Andreeva, V., James Cooper, W., Yelick, P. C., Craig Albertson, R. [jove.com]

Etiology

Environmental risk factors for orofacial clefts There are several recognized environmental risk factors and multiple genes involved in the etiology of orofacial clefts, which means the etiology is complex and heterogeneous. [f1000research.com]

Embryology Etiology The development of CLP is dependent on the interaction of environmental factors and genetic predisposition Genetic predisposition Family history: multifactorial inheritance pattern ( Mendelian inheritance is rare) An affected parent [amboss.com]

Lecturer, SEGi University Published on Mar 23, 2013 At the end of this lecture, students should be able to: Develop an understanding terms Cleft lip & Palate Develop an understanding of incidence of the condition Describe the etiology and pathogenesis [slideshare.net]

In Nigeria, many deformities have been attributed to supernatural forces, [25], [26] as in the Hausa/Fulani, who attribute the etiology to the “will of God." [25] In another study on the cultural beliefs of Nigerians about the etiology of cleft deformities [jcsjournal.org]

Over the years many different classification systems based on morphological, anatomical or etiological features of OFCs have been proposed. However, postnatal classification may not be applicable to prenatal findings. [wjgnet.com]

Epidemiology

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.de]

To date, little is known regarding the epidemiology and pattern of orofacial clefts in Tanzania. [bmcoralhealth.biomedcentral.com]

However, there have been very few epidemiological studies of oral clefts in Thais. Objectives To describe the epidemiology and factors associated with oral clefts in Thais. [degruyter.com]

Epidemiology References: [1] [2] [3] [4] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]

Prevention

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.de]

Prevention Identification of modifiable risk factors is the first step towards primary prevention: Pre-pregnancy planning seems to reduce risk. [patient.info]

Having certain infections during pregnancy, like rubella (also called German measles) What can you do to help prevent cleft lip and cleft palate in your baby? You can’t always prevent cleft lip and cleft palate in your baby. [marchofdimes.org]

Prevention While little is known about how to prevent clefts, researchers from the California Birth Defects Monitoring Program found that women considering pregnancy may be able to reduce the risk of facial clefts (and possibly other birth defects) in [encyclopedia.com]

Speech During speech, the palate controls air flow, preventing air from escaping through our nostrils. In addition, many speech sounds are produced by touching tongue to palate. [cleftresources.com]

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