Presentation
Bacteremia due to Erysipelothrix rhusiopathiae is rare; the most common presentation reported in the literature is endocarditis. [ncbi.nlm.nih.gov]
A neck mass, often cystic, is a common presenting symptom of patients with oropharyngeal cancer. [msdmanuals.com]
Entire Body System
- Swelling
In addition to pain and swelling of the testes, systemic symptoms may develop, such as malaise, fever, nausea, headache, and myalgias. [merckmanuals.com]
In boys or men with mumps, orchitis develops between 4 and 7 days after the salivary gland swelling. The testis swells and is painful. Sometimes both testes are affected. Fever, nausea, headache, and muscle aches may also occur. [msdmanuals.com]
To help with pain and swelling, place an ice pack (ice cubes in a plastic zip lock bag, wrapped in a thin towel) over the scrotum for no more than 20 minutes every 3 to 6 hours during the first 24 to 48 hours. [fairview.org]
Patients may experience the rapid onset of pain and swelling, or the symptoms may appear more gradually. [emedicinehealth.com]
- Fever
We report a 32-year-old man with oropharyngeal cancer who developed aspiration pneumonia and E. rhusiopathiae bacteremia, and presented with fever, chills, dyspnea, and productive cough with purulent sputum. [ncbi.nlm.nih.gov]
Other symptoms include high fever, nausea, and vomiting. You may have pain with urination or sex. Treatment of bacterial orchitis is antibiotics for 10 days. Treatment for viral (mumps) orchitis is aimed at symptom relief only. [fairview.org]
Comfort measures, such as over-the-counter medications to reduce pain and fever, may be advised. Antibiotics will be prescribed if a bacterial infection is present. [winchesterhospital.org]
2014 Diagnosis Management Patient education Contact tracing Follow up Further information Disclaimer Diagnosis Clinical Unilateral swelling and tenderness of epididymis, +/- testicle tender and swollen spermatic cord exclusion of testicular torsion fever [sahealth.sa.gov.au]
Other symptoms include high fever, nausea, vomiting, pain with urination, or pain from straining with a bowel movement, groin pain, pain with intercourse, and simply feeling ill. [webmd.com]
- Fatigue
And patients usually suffer severe fatigue during treatment. Although the burns, fatigue, and swallowing problem usually go away after therapy, patients may have another problem for the rest of their lives: dryness of the mouth and throat. [webmd.com]
Other symptoms include: Tenderness Feeling of heaviness in the scrotum Blood in the urine or semen Pain during urination, ejaculation, or sexual intercourse Generalized groin pain Viruses and bacteria may also cause body-wide symptoms such as fatigue, [winchesterhospital.org]
Symptoms of orchitis may include the following: Testicular swelling Testicular redness Testicular pain and tenderness Fever and chills Nausea Malaise and fatigue Headache Body aches Pain with urination In epididymo-orchitis, the symptoms may come on and [emedicinehealth.com]
The advantages offered to the surgeon include a three‐dimensional view, 360° robotic arm movement (in restricted spaces with precision of movement), hand tremor filtration and lack of muscle fatigue. [cochranelibrary.com]
- Weight Loss
See a doctor if any of the following symptoms are present: A sore throat that persists Pain or difficulty with swallowing Unexplained weight loss Voice changes Ear pain A lump in the back of the throat or mouth A lump in the neck Cleveland Clinic News [my.clevelandclinic.org]
The possible signs of oropharyngeal cancer are: A sore throat that persists for over 2 weeks Throat pain or difficulty swallowing Unexplained rapid weight loss Voice changes (more hoarse) Ear pain A lump in the back of the throat or mouth A lump in the [en.wikipedia.org]
Weight loss for no known reason. Ear pain. A lump in the back of the mouth, throat, or neck. A white patch on the tongue or lining of the mouth that does not go away. Coughing up blood. [cancer.gov]
- Pathologist
[…] give radiation treatments Head and Neck Surgeons: Doctors who remove tumors with specialized operations Plastic and Reconstructive surgeons: Doctors who replace tissues removed during cancer surgery to restore function and appearance Dentists Speech pathologists [mdanderson.org]
Biopsy : The removal of cells or tissues so they can be viewed under a microscope by a pathologist to check for signs of cancer. A fine-needle biopsy is usually done to remove a sample of tissue using a thin needle. [cancer.gov]
Reporting to this registry, established in 1958, is compulsory for clinicians and pathologists/cytologists diagnosing a cancer. [doi.org]
Respiratoric
- Sore Throat
A few weeks ago Jason found out that his two month long sore throat was in fact a bit of cancer growing on his esophagus. The good news is that it's localized and very much treatable. He gets started later this week. [greendayauthority.com]
See a doctor if any of the following symptoms are present: A sore throat that persists Pain or difficulty with swallowing Unexplained weight loss Voice changes Ear pain A lump in the back of the throat or mouth A lump in the neck Cleveland Clinic News [my.clevelandclinic.org]
The possible signs of oropharyngeal cancer are: A sore throat that persists for over 2 weeks Throat pain or difficulty swallowing Unexplained rapid weight loss Voice changes (more hoarse) Ear pain A lump in the back of the throat or mouth A lump in the [en.wikipedia.org]
Symptoms and Signs Oropharyngeal cancer symptoms vary slightly depending on the subsite but typically patients present with sore throat, dysphagia, odynophagia, dysarthria, and otalgia. [msdmanuals.com]
Gastrointestinal
- Overeating
Two cases were examined over 4 to 6 years. Late-RAD was assessed per MBS impairment profile (MBSImP™©), Penetration-Aspiration Scale (PAS), Performance Status Scale for Head and Neck cancer (PSS-HN), and MD Anderson Dysphagia Inventory (MDADI). [ncbi.nlm.nih.gov]
You may use over-the-counter medicines to control pain, unless you were given another medicine. [fairview.org]
Analysis of 7 pooled registries revealed a statistically significant reduction in the incidence of oral cavity cancer in men (annual percent change [APC] = -3.1) and a nonsignificant decrease in women (APC = -4.5) over the period from 1991 to 2001. [agenciasinc.es]
The dye is spread over the abnormal area and if there is cancer, it will stain the malignant tissues blue. Another method uses laser light. [web.archive.org]
- Dysphagia
Limited data examine these neuropathies after oropharyngeal cancer, particularly as it relates to late radiation-associated dysphagia (late-RAD). Two cases were examined over 4 to 6 years. [ncbi.nlm.nih.gov]
[…] exposureCertain genetic changes including: P53 mutation and CDKN2A (p16) mutations.High-risk lesions: Erythroplakia Speckled erythroplakia Chronic hyperplastic candidiasisMedium-risk lesions: Oral submucosal fibrosis Syphilitic glossitis Sideropenic dysphagia [en.wikipedia.org]
To prevent post-surgical dysphagia in oral or oropharyngeal cancer patients, crico-pharyngeal myotomy and laryngeal suspension are recommended; however, its indication has been controversial. [ci.nii.ac.jp]
Symptoms and Signs Oropharyngeal cancer symptoms vary slightly depending on the subsite but typically patients present with sore throat, dysphagia, odynophagia, dysarthria, and otalgia. [msdmanuals.com]
- Dysphagia
Limited data examine these neuropathies after oropharyngeal cancer, particularly as it relates to late radiation-associated dysphagia (late-RAD). Two cases were examined over 4 to 6 years. [ncbi.nlm.nih.gov]
[…] exposureCertain genetic changes including: P53 mutation and CDKN2A (p16) mutations.High-risk lesions: Erythroplakia Speckled erythroplakia Chronic hyperplastic candidiasisMedium-risk lesions: Oral submucosal fibrosis Syphilitic glossitis Sideropenic dysphagia [en.wikipedia.org]
To prevent post-surgical dysphagia in oral or oropharyngeal cancer patients, crico-pharyngeal myotomy and laryngeal suspension are recommended; however, its indication has been controversial. [ci.nii.ac.jp]
Symptoms and Signs Oropharyngeal cancer symptoms vary slightly depending on the subsite but typically patients present with sore throat, dysphagia, odynophagia, dysarthria, and otalgia. [msdmanuals.com]
- Odynophagia
Symptoms and Signs Oropharyngeal cancer symptoms vary slightly depending on the subsite but typically patients present with sore throat, dysphagia, odynophagia, dysarthria, and otalgia. [msdmanuals.com]
[…] modified by cutting out the consumption of tobacco and alcohol. 36 Clinical manifestations, diagnosis and evaluation Early oropharyngeal tumors are often asymptomatic, but advanced tumors produce local pain, ear ache, cervical lymphadenopathy, trismus, odynophagia [scielo.org.mx]
Jaw & Teeth
- Trismus
[…] likely not modified by cutting out the consumption of tobacco and alcohol. 36 Clinical manifestations, diagnosis and evaluation Early oropharyngeal tumors are often asymptomatic, but advanced tumors produce local pain, ear ache, cervical lymphadenopathy, trismus [scielo.org.mx]
Ears
- Otalgia
Symptoms and Signs Oropharyngeal cancer symptoms vary slightly depending on the subsite but typically patients present with sore throat, dysphagia, odynophagia, dysarthria, and otalgia. [msdmanuals.com]
Psychiatrical
- Aggressive Behavior
Other types, such as bilateral embryonal carcinoma, should be treated with caution, due to the extremely aggressive behavior of this tumor, as the reported survival rate is only 39% (5). [ncbi.nlm.nih.gov]
Workup
Microbiology
- Human Papillomavirus
Human papillomavirus infections in laryngeal cancer. Head Neck. 2011;33:581–6. PubMed Google Scholar 117. Hobbs CG, Sterne JA, Bailey M, et al. Human papillomavirus and head and neck cancer: a systematic review and meta-analysis. [doi.org]
Human papillomavirus and cervical cancer -- burden and assessment of causality. J Natl Cancer Inst Monogr 2003 ;31: 3 - 13 6. Gillison ML, Shah KV. Role of mucosal human papillomavirus in nongenital cancers. [content.nejm.org]
The number of women diagnosed with oropharyngeal cancer related to the human papillomavirus (HPV) is increasing in the United States. [ncbi.nlm.nih.gov]
C., Redmond, K.P. (2010) Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer. [scindeks.ceon.rs]
Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 2008;100(6):407-20. [kjorl.org]
Treatment
Free lodging near treatment. A 24/7/365 live helpline. Rides to treatment. This is far from a complete list, but it makes one thing clear. When it comes to cancer, we are the only organization attacking from every angle. [cancer.org]
Treatment Options by Stage For information about the treatments listed below, see the Treatment Option Overview section. [cancer.gov]
Keep in mind that all cancer treatments have side effects, both short term and long term, but it is the MD Anderson physicians’ goal to factor in the effect of each treatment on a person’s quality of life as part of the treatment decision-making for any [mdanderson.org]
Treatment with epithelial growth factor receptor inhibitors (EGFRIs) is associated with a good response. [ncbi.nlm.nih.gov]
Prognosis
Its prognosis is largely dependent upon tumour-stage at the time of diagnosis. [eurjcancerprev.com]
In oral and oropharyngeal cancer, the presence of regional neck metastasis strongly influences treatment planning and survival prognosis. A number of imaging techniques can be utilized in the clinic for diagnosis and staging. [ncbi.nlm.nih.gov]
“The prognosis is good, and the survival rate is high. Unfortunately the treatment will be rough on my body, and my voice.” [jambase.com]
Pemeriksaan patologi jaringan dan sitologi cairan asites penting dalam penentuan stadium klinik, dan hal ini berpengaruh terhadap pilihan pengobatan dan prognosis penderita. [ejournal.unsrat.ac.id]
Correlation with HPV and p16, p53, EGFR, Rb and theier effects on the prognosis were also inconsistently repeated among literatures. [ndsl.kr]
Etiology
The etiology and pathogenesis of these tumors are not clearly defined, but some studies have shown that etiology is related to genetic origin. [ejournal.unsrat.ac.id]
This article discusses the etiology and clinical presentation of HPV-positive and HPV-negative oropharyngeal cancer, noting distinctions between the 2 types. Recommendations for screening and prevention are provided. [ncbi.nlm.nih.gov]
Etiology The exact etiology for this tumor type has not been elucidated. Epidemiology Frequency The US incidence of dysgerminomas has remained unchanged over the last 30 years. [emedicine.medscape.com]
HPV type 16 causes 60% of oropharyngeal cancers, and patients have become younger (median age 57 years, and bimodal peaks at 30 years and 55 years) as HPV infection has emerged as an etiology. [msdmanuals.com]
Epidemiology
The incidence of HPV-associated oropharyngeal cancers is rapidly increasing in most Western countries, but detailed epidemiological data are not available for the Italian population. [ncbi.nlm.nih.gov]
Discussion This epidemiologic study provides support for the association between HPV and a subgroup of oropharyngeal cancers. [content.nejm.org]
Archives of Neurology, 56(5): 540 [ CR ] [ EČ ][ GS ] Zucconi, M. (2004) Epidemiology and clinical findings of restless legs syndrome. Sleep Medicine, 5(3): 293-299 [scindeks.ceon.rs]
Epidemiology Frequency The US incidence of dysgerminomas has remained unchanged over the last 30 years. [emedicine.medscape.com]
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Pathophysiology
Pathology and Forensic Medicine (340) Internal Medicine (289) Oncology, Radiation Therapy (237) Surgery, Traumatology and Orthopaedics (162) Physiology and Pathophysiology (161) Medical Chemistry and Biochemistry (148) Paediatrics, Neonatology (109) Genetics [portal.mefanet.cz]
Pathophysiology Typically, germ cells are encapsulated at birth within the primordial follicle. If they somehow escape encapsulation, cell death usually occurs. [emedicine.medscape.com]
The etiology and pathophysiology of testicular dysfunction in man. Fertil Steril 1978;29: 481-91 [PubMed] [Google Scholar] 12. Erpenbach K. [ncbi.nlm.nih.gov]
Prevention
Recommendations for screening and prevention are provided. [ncbi.nlm.nih.gov]
Prevention To help reduce your chance of orchitis: Get vaccinated with the MMR vaccine. Practice safe sex, including wearing a latex condom to prevent STIs. Get prompt treatment for any infections. [winchesterhospital.org]
The rich blood supply and lymphatic supply in the testicle prevent most infections from obtaining a strong foothold in this organ. [britannica.com]
Prevention To prevent orchitis: Get immunized against mumps, the most common cause of viral orchitis Practice safe sex, to help protect against STIs that can cause bacterial orchitis Oct. 10, 2018 [mayoclinic.org]