Focal glomerulosclerosis, with the nephrotic syndrome and progressive renal insufficiency, developed in a 15-year-old boy who presented initially 1 year earlier with orthostatic proteinuria. [ncbi.nlm.nih.gov]

Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty. [books.google.com]

Presentation Positive urinary protein dipstick tests during the day but negative tests with early morning urine. All other investigations of renal function and urinary tract anatomy are normal. [patient.info]

It is not present when the patient is in bed. Synonym: postural proteinuria [medical-dictionary.thefreedictionary.com]

• Weight Gain

  Age and weight gain also increase the risk. [healthcommunities.com]

• Lymphadenopathy

  Other uncommon causes such as pancreatic neoplasm, paraaortic lymphadenopathy, retroperitoneal tumor, abdominal aortic aneurysm, overarching testicular artery, LRV duplication, and ectopic ventral right renal artery and strangulating fibrolymphatic tissue [wjgnet.com]

• Polydipsia

  […] on urinalysis Systemic lupus erythematosus Recurrent fever, butterfly rash, arthritis, hematuria, growth failure, multisystem involvement Positive antinuclear antibody, pancytopenia, decreased complement C3 and C4 levels Diabetes mellitus Polyuria, polydipsia [aafp.org]

• Heart Disease

  Heart Disease/Heart Failure Studies have found that protein in urine can be an indicator of possible risk of heart disease or heart failure, but this link was only seen in Caucasians. [belmarrahealth.com]

  The book provides you with all the at-a-glance information you need for a quick overview of common issues from nutrition, allergy, infectious disease, and adolescent medicine, to cancer and heart disease. [books.google.com]

  Patients with protein in their urine are more likely to suffer from heart disease. [kidneyresearchuk.org]

• Fracture

  Thrombosis, stent migration, fracture and restenosis are the complications of the endovascular stenting but they are rare[ 30 ]. CONCLUSION NCS is a type of spectral disease and varies in severity and symptoms. [wjgnet.com]

It is associated with good long-term prognosis. [3, 4, 5] Accompanying findings in patients with glomerular damage may include the following (see Workup ): Active urine sediment - Dysmorphic red blood cells and red cell casts Hypoalbuminemia Lipiduria [emedicine.medscape.com]

Her overt orthostatic proteinuria disappeared after a treatment of angiotensin-converting enzyme (ACE) inhibition. [ncbi.nlm.nih.gov]

Most people opt for allopathic treatment in their advanced stages of orthostatic proteinuria. [kidneyfailuretreatment.in]

Treatment of Proteinuria Proteinuria is not a specific disease. So its treatment depends on identifying and managing its underlying cause. If that cause is kidney disease, appropriate medical management is essential. [webmd.com]

It resolves when the aforementioned problems resolve and requires no treatment. [dummies.com]

Prognosis The long-term prognosis of true orthostatic proteinuria is excellent. Although many of the patients continue to have proteinuria of minor degree for several decades, they do not get hypertension or renal impairment. [patient.info]

The 20-year prognosis of patients with fixed and reproducible orthostatic proteinuria is excellent. [ncbi.nlm.nih.gov]

The prognosis is normal up to 40 years following diagnosis. Although many of the patients continue to have proteinuria of minor degree for several decades they do not get hypertension or renal impairment. [gpnotebook.co.uk]

The 20-year prognosis of patients with fixed and reproducible orthostatic proteinuria is excellent. FULL TEXT [annals.org]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

There are several theories, though the precise etiology is not known. [renalfellow.blogspot.com]

Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. [icd10data.com]

Protein losses of over 2000mg/24 hours in adults and over 40 mg/24 hours in children usually indicates a glomerular etiology. Preeclampsia (toxemia of pregnancy) causes massive loss of protein in the urine. [rnceus.com]

Etiology of Proteinuria Transient or Functional Proteinuria As many as 30 to 50 percent of children with proteinuria may have transient, non-repetitive proteinuria. 6 Transient proteinuria can occur with strenuous exercise, emotional stress, exposure [aafp.org]

Epidemiology It is most common in children and young adults and most common in young adult males. The prevalence is 2-5% of adolescents and rare in those older than 30 years. [patient.info]

Dodge WF, West EF, Smith EH, Bruce H 3rd (1976) Proteinuria and hematuria in schoolchildren: epidemiology and early natural history. J Pediatr 88:327–347 CrossRef PubMed Google Scholar 3. [link.springer.com]

Outcomes Reprinted by permission from Macmillan Publishers Ltd: Kidney International Supplements (vol 3, issue 1, January 2013), copyright 2013 In patients with advanced CKD, proteinuria is the strongest predictor of time to end-stage renal disease. [21] Epidemiology [online.epocrates.com]

Epidemiology of proteinuria. A study of 4,807 schoolchildren. J Pediatr. 1968;73:825–32. 18. Norman ME. An office approach to hematuria and proteinuria. Pediatr Clin North Am. 1987;34:545–60. 19. [aafp.org]

Despite its frequent occurrence, the underlying pathophysiologic mechanisms remain unclear. The following three possibilities have been reviewed: (1) a normal variant; (2) a glomerular abnormality; (3) a hemodynamic abnormality. [ncbi.nlm.nih.gov]

Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices. [books.google.com]

The pathophysiologic mechanisms of proteinuria can be classified as glomerular, tubular or overflow ( Table 2 7 ). [aafp.org]

There are three different pathophysiological mechanisms that may lead to proteinuria: damage to the glomeruli (glomerular), damage to the tubules (tubular), or overproduction of low-molecular-weight proteins (overflow). [amboss.com]

[…] where the test may be helpful Diagnosis of orthostatic proteinuria As a second-order test for additional characterization of proteinuria of less than 3 grams/24 hours, particularly in children or adolescents Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]

Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.com]

Damage to the tubules can prevent protein from being reabsorbed. Proteinuria may also develop when too much of a small protein is present in the blood and the tubules cannot reabsorb all of it. [labtestsonline.org.au]

You may have problems with urination if you have Kidney failure Urinary tract infections An enlarged prostate Bladder control problems like incontinence, overactive bladder, or interstitial cystitis A blockage that prevents you from emptying your bladder [icdlist.com]

Can proteinuria in children be prevented or avoided? Proteinuria cannot be prevented or avoided. However, good kidney health requires lots of water. Regularly drinking water will flush out waste from your kidneys. [familydoctor.org]

[…] come from two classes of drugs: ACE inhibitors (angiotensin-converting enzyme inhibitors) ARBs (angiotensin receptor blockers) Proper treatment -- especially in patients with chronic disease such as diabetes and high blood pressure -- is essential to prevent [webmd.com]