However, pregnancy seems to hasten presentation. The incidence of otosclerosis also increases with age. [asams.org]

Differential diagnosis Differential diagnosis should include minor ossicular malformations presenting with a normal otoscopy, a conductive hearing loss, and abolished stapedial reflexes. [orpha.net]

The CT and clinical findings are considered typical, and a family history need not be present to suggest the diagnosis of X-linked congenital hearing loss. In four patients reported by Talbot and Wilson ( 4 ), a family history was not present. [ajnr.org]

Presents new contributors for 14 chapters to provide you with authoritative coverage and the dynamic perspectives of leaders in the field. [books.google.de]

• Ankylosis

  Affiliated tissues include bone, and related phenotypes are bilateral conductive hearing impairment and stapes ankylosis [malacards.org]

  Congenital stapes ankylosis: study of 28 cases and surgical results.. Laryngoscope. 2006; 116(7):1153-1157. http://www.ncbi.nlm.nih.gov/pubmed/16826051. Hara A, Ase Y, Kusakari J, Kurosaki Y. [rarediseases.info.nih.gov]

  The otosclerotic focus may be asymptomatic, or if present in the area of foot plate of stapes it may give rise to ankylosis of foot plate with resultant conductive deafness. [drtbalu.co.in]

  INTRODUCTION Otosclerosis is a disease of otic capsule in which new vascular spongy bone formation causes ankylosis or fixation of the foot plate of the stapes and progressive conductive deafness.  Otosclerosis can result in conductive and/or sensorineural [slideshare.net]

  [oto- + G. sklērōsis, hardening] otosclerosis /oto·scle·ro·sis/ ( -sklĕ-ro´sis ) a condition in which otospongiosis may cause bony ankylosis of the stapes, resulting in conductive hearing loss.otosclerot´ic otosclerosis (ō′tō-sklə-rō′sĭs) n. [medical-dictionary.thefreedictionary.com]

• Hearing Impairment

  X-linked Disorders Alport syndrome X-linked mixed hearing impairment with stapes fixation and perilymphatic gusher. Hereditary causes of hearing loss are suspected in all cases of hearing impairment. [pediatric-ent.com]

  CAUSES OF HEARING IMPAIRMENT If there is some difficulty in the external (outer) or middle ear, a conductive hearing impairment occurs. [potomacaudiology.com]

  Affiliated tissues include bone, and related phenotypes are bilateral conductive hearing impairment and stapes ankylosis [malacards.org]

  Affected females manifest bilateral, moderate hearing impairment that affects the high frequencies ( Fig. 2 C). [academic.oup.com]

  Synonym: otospongiosis Otosclerosis (OTSC) is the single most common cause of hearing impairment. [patient.info]

Treatments for Mixed Hearing Loss Audiologists recommend taking care of the conductive component first. [hearingloss.org]

Medical treatment -- is generally ineffective Lictor (2013) reviewed all medical treatments and concluded that there is no medical treatment proven to work. [dizziness-and-balance.com]

CLOSE Medical Disclaimer The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. [diseaseinfosearch.org]

References: [1] [2] Diagnostics References: [1] [2] [4] Treatment [amboss.com]

Diagnosis - Progressive hearing loss stapes fixation Prognosis - Progressive hearing loss stapes fixation Not supplied. Treatment - Progressive hearing loss stapes fixation Not supplied. [checkorphan.org]

Prognosis OTSC treated surgically has a good prognosis in the vast majority of cases. The rate of hearing deterioration with time after stapedotomy does not exceed that due to presbyacusis [ 21 ] . [patient.info]

Prognosis In 90 of 100 patients, the operation is completely successful, in that the hearing is markedly improved. In 8 out of 100 patients, the hearing is improved, but not quite as much as hoped for. [bcm.edu]

Prognosis People with otosclerosis almost never become totally deaf, and will usually be able to hear with a hearing aid or with surgery plus a hearing aid. [medical-dictionary.thefreedictionary.com]

[…] results with minimal complications. [4] [7] Last updated: 1/30/2017 Surgical treatment of isolated deafness with stapes fixation allows good functional results regardless of age or type of surgery. [4] If other symptoms or complications are present, prognosis [rarediseases.info.nih.gov]

Etiology The etiology of otosclerosis is still unknown. Otosclerosis appears to be a multifactorial disease. Autosomal dominant and a low penetrance (40%) transmission is observed in familial cases. [orpha.net]

What are 3 etiologies of sudden SNHL? Vascular occlusion Viral etiology Vestibular schwannoma 1% cases What is presbycusis? What causes it? Bilateral SNHL. Symmetric, slowly progressive. Cumulative effect of aging. [quizlet.com]

Etiology Pathophysiology Clinical features Symptoms may increase during pregnancy or following menopause because of hormonal changes! References: [1] [2] Diagnostics References: [1] [2] [4] Treatment [amboss.com]

"The etiology of otosclerosis: A combination of genes and environment". The Laryngoscope. 120 (6): 1195–202. doi : 10.1002/lary.20934. [en.wikipedia.org]

Epidemiology References: [1] [2] Epidemiological data refers to the US, unless otherwise specified. Etiology Pathophysiology Clinical features Symptoms may increase during pregnancy or following menopause because of hormonal changes! [amboss.com]

Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular [books.google.com]

Summary Epidemiology The prevalence of symptomatic otosclerosis is estimated as 0.1 to 0.5% of the population in the United-States and Western Europe, thus this is not a rare disease. [orpha.net]

Epidemiology Histological OTSC is present in around 2.5% of people [ 5 ]. However, the clinical manifestations are seen in only about 0.3%. [patient.info]

Etiology Pathophysiology Clinical features Symptoms may increase during pregnancy or following menopause because of hormonal changes! References: [1] [2] Diagnostics References: [1] [2] [4] Treatment [amboss.com]

One genome-wide analysis associates otosclerosis with variation in RELN gene. [9] Loci include: Pathophysiology [ edit ] The pathophysiology of otosclerosis is complex. [en.wikipedia.org]

Pathophysiology: The primary pathological change occurs in the bony labyrinth with secondary effects upon middle ear and inner ear function. [drtbalu.co.in]

Pathophysiology of otosclerosis. Otol Neurotol 22:249–257. McKenna MJ, Kristiansen AG, Bartley ML, Rogus JJ, Haines JL.1998. Association of COL1A1 and otosclerosis: evidence for a shared genetic etiology with mild osteogenesis imperfecta. [dizziness-and-balance.com]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.de]

[…] characterized by hearing loss, fixation of stapes (ear bone which causes conductive deafness if it becomes fixed and immovable) and reduced vestibular response Symptoms - Progressive hearing loss stapes fixation Causes - Progressive hearing loss stapes fixation Prevention [checkorphan.org]

Although hearing improvement can be immediate, packing placed into the ear canal at the end of the surgery prevents patients from experiencing their new hearing for a week or so. [health.ucsd.edu]

In selected cases, medication may be prescribed in an attempt to prevent further hair cell loss and subsequently prevent further inner ear damage. This medication is sodium fluoride. [potomacaudiology.com]

Hearing is improved immediately, although packing placed into the ear canal at the end of the surgery prevents patients from experiencing their new hearing for a week or so. [seanpalaciosmd.com]