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Ovarian Adenoma


Presentation

  • Presentation A young woman presents with dull, chronic pain in the lower abdomen. An ultrasound was performed. Caption: Sagittal view of right adnexa Description: A large complex cystic mass is seen in the right adnexa.[sonoworld.com]
  • Pallor was present; she was normotensive and had bilateral pitting pedal odema. On abdominal examination, abdomen was grossly distended, engorged veins present, Fluid thrill was present. Abdominal girth at the level of the umbilicus was 42 inches.[casesjournal.biomedcentral.com]
  • However, they do present the risk of turning cancerous and hence, treating them is a wise approach.[fertilityproregistry.com]
  • They are usually asymptomatic and the patient presents with abdominal swelling because of its size.[medcraveonline.com]
  • We present the former case and discuss the latent risk of failure to identify this entity. Case presentation A 36-year-old woman with a sellar tumor was referred to our hospital with suspected ovarian hyperstimulation.[bmcresnotes.biomedcentral.com]
Euthyroid
  • Patient was euthyroid and was not on any medications. On General examination her vitals were stable. Systemic examination showed no abnormality in respiratory and cardiovascular system.[medcraveonline.com]
Epigastric Tenderness
  • In physical examination, there were no positive findings, except epigastric pain with diffuse abdominal distension and moderate epigastric tenderness without guarding. No well-defined mass was detected on palpation.[jmrh.mums.ac.ir]
Ulcer
  • […] the participants with both complete sigmoidoscopies and risk factor and dietary questionnaires, we excluded 7571 persons for the following reasons: self-reported history of cancer other than basal-cell skin cancer ( n 2363); self-reported history of ulcerative[ajcn.nutrition.org]
Neglect
  • Sometimes, neglected or misdiagnosed tumors (similar to our case) can become so huge that they seem like a term pregnancy (4).[jmrh.mums.ac.ir]
Adnexal Mass
  • Case report First Online: 05 March 2016 Abstract Introduction Adnexal masses in pregnancy occur in 0.5–2/1000 pregnancies. (1) More than 90 % of cysts are benign.[link.springer.com]
  • Ultrasound typically large cystic adnexal mass multilocular with numerous thin septations loculations may contain low-level internal echogenicity due to increased mucin content different locules may contain various degrees of echogenicity MRI Mucinous[radiopaedia.org]
  • masses Increasing abdominal girth 15% are bilateral Imaging findings Average 5-10cm (frequently grow larger) May be indistinguishable from simple cysts Or they may have thin septations and occasionally papillary projections Tend to be unilocular, but[learningradiology.com]
  • It should be noted that metastatic cancers can sometimes initially present as adnexal masses.[aafp.org]
  • Página 406 - Goldstein SR, Subramanyam B, Snyder JR et al: The postmenopausal cystic adnexal mass, the potential role of ultrasound in conservative management. Obstet Gynaecol 73:8, 1989. ‎ Página 46 - Kelly, SJ (1977).[books.google.es]

Workup

  • (See Presentation, DDx, and Workup.)[emedicine.medscape.com]
  • If on the unenhanced-CT the density is equal to or below 10 HU the lesion is considered to be an adenoma and no further workup is neccessary If the density is more than 10 HU the wash out should be calculated.[radiologyassistant.nl]
Ovarian Mass
  • The case was managed by abdominal hysterectomy and bilateral salphingectomy of the hematosalphinx, which had formed a tubo-ovarian mass. One ovary was preserved.[ncbi.nlm.nih.gov]
  • Ovarian mass was explored out, pedicles traced and dissection of ureter done, pedicles clamped and ovarian mass was excised and sent for frozen section which reported as mucinous cystadenoma of ovary.[medcraveonline.com]
  • The majority of ovarian masses are cystic, and many of them are functional which may spontaneously resolve (2).[jmrh.mums.ac.ir]
  • mass with vascularization in some of the septations Benign cystic lesions: Mucinous cystadenoma with a septated cystic ovarian mass Benign cystic lesions: Mucinous cysteadenoma Benign cystic lesions: Mucinous cysteadenoma Benign cystic lesions: Mucinous[ultrasoundcases.info]
  • In conclusions, germ cell tumours the most important causes for the giant ovarian masses in children. Epithelial tumors should not be forgotten in the differential diagnosis Key words: Adolescent, Ovarian Cysts, Ovarian Neoplasms, Serous Cystadenoma[scopemed.org]
Multilocular Cyst
  • cysts containing fluid of various viscosity.[radiopaedia.org]
  • Cut section showed thick brownish coloured fluid oozing out from multilocular cyst was seen. Microscopic examination of serial sections revealed a cyst wall lined by tall columnar epithelium with vocuolated cytoplasm.[medcraveonline.com]
  • The cyst is usually unilocular, but it can be multilocular. Cysts are filled with clear, serous fluid [1] .[cancerwall.com]
  • The ultrasound result is scored 1 point for each of the following characteristics: multilocular cysts, solid areas, metastases, ascites and bilateral lesions.[patient.info]

Treatment

  • The advances made in the treatment of gynecologic malignancies are due, in part, to the clinical studies performed by many of the contributors to this volume.[books.google.com]
  • Treatment The three basic treatment methods for ovarian cancer, including endometroid adenoma, are local surgical resection of the cancerous cells, intraperitoneal chemotherapy, (drugs are delivered directly to the affected area) and systemic chemotherapy[knowcancer.com]
  • […] differentiating malignant from benign masses Malignancies are rich in neovascularization and therefore have lower resistive and pulsatile indices Gray-scale ultrasound for diagnosis of ovarian malignancy is 62 – 100% sensitive and 77 – 95% specific Treatment[learningradiology.com]
  • Treatment and prognosis A mucinous cystadenoma is benign with excellent prognosis (c.f. borderline mucinous tumors of the ovary or mucinous cystadenocarcinoma of the ovary).[radiopaedia.org]
  • In fact, earlier diagnosis is associated with less invasive treatment approaches and prevention of tissue destruction.[jmrh.mums.ac.ir]

Prognosis

  • Treatment and prognosis A mucinous cystadenoma is benign with excellent prognosis (c.f. borderline mucinous tumors of the ovary or mucinous cystadenocarcinoma of the ovary).[radiopaedia.org]
  • Distant metastatic disease Malignant pleural effusion Pulmonary parenchymal metastases Liver or splenic parenchymal metastases Metastases to the supraclavicular lymph nodes or skin Cancer staging dictates treatment and predicts prognosis Stage 1 Usually[learningradiology.com]
  • (Outcomes/Resolutions) The prognosis of Benign Mucinous Cystadenoma of Ovary is excellent with suitable treatment The prognosis is generally good when the lesions are small and found below the ovarian surface.[dovemed.com]

Etiology

  • Etiology Thought to largely derive from ovarian epithelial inclusions, which itself is derived from fallopian tube epithelium. Location They can be bilateral in 15% of cases.[radiopaedia.org]
  • Diagnostic laparoscopy can be used in masses of uncertain etiology, as well. Surgery is the treatment of choice for serous cystadenomas. Unilateral salpingo-oophorectomy is commonly considered in huge tumors (7).[jmrh.mums.ac.ir]
  • Ovarian cyst is a common disorder in young women with various etiologies.[bmcresnotes.biomedcentral.com]
  • (Etiology) The exact cause of Benign Mucinous Cystadenoma of Ovary is unknown; they are thought to occur spontaneously Researchers have documented certain genetic changes within the tumor.[dovemed.com]

Epidemiology

  • Epidemiology The estimated peak incidence is at around 30-50 years of age. They comprise approximately 80% of mucinous ovari...[najdi.si]
  • Epidemiology Benign ovarian tumours occur in 30% of females with regular menses (eg, luteal cysts as incidental findings on pelvic scans) and 50% of females with irregular menses.[patient.info]
  • (See Epidemiology, Prognosis, Treatment, and Medication.)[emedicine.medscape.com]
  • […] female genital tract understand the concept of borderline tumors and how to distinguish them from carcinomas be able to describe clinical features including relevant associations be able to suggest possible clinical outcomes and response to treatment Epidemiology[med-ed.virginia.edu]
  • PMID 8275457 Epidemiology and primary prevention of cancers of the breast, endometrium, and ovary. A brief overview. Kelsey JL, Whittemore AS Annals of epidemiology. 1994 ; 4 (2) : 89-95.[atlasgeneticsoncology.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Functional cysts The median menstrual cycle lasts 28 days, beginning with the first day of menstrual bleeding and ending just before the subsequent menstrual period.[emedicine.medscape.com]

Prevention

  • In fact, earlier diagnosis is associated with less invasive treatment approaches and prevention of tissue destruction.[jmrh.mums.ac.ir]
  • Hence, there are no known methods to prevent the tumor occurrence. Early diagnosis with close monitoring and treatment of the tumor is important. A timely tumor recognition and prompt treatment will help in having optimal ...[najdi.si]
  • The reason for this precaution is to prevent spillage of mucinous material within the peritoneal cavity and possible development of Pseudomyxomaperitonei.[medcraveonline.com]
  • How can Benign Mucinous Cystadenoma of Ovary be Prevented? The cause of Benign Mucinous Cystadenoma of Ovary is unknown. Hence, there are no known methods to prevent the tumor occurrence.[dovemed.com]

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