HGSC often presents as a very large cystic and solid tumor with frequent areas of hemorrhage and necrosis. [ncbi.nlm.nih.gov]

The major genetic risk factor for ovarian cancer is a mutation in BRCA1 or BRCA2 DNA mismatch repair genes, which is present in 10% of ovarian cancer cases. Only one allele need be mutated to place a person at high risk. [en.wikipedia.org]

A screening test is a test that is done when no symptoms are present. Examples of screening tests are colonoscopy for colorectal cancer and the Pap test for cervical cancer. Currently, there is no screening test for ovarian cancer. [acog.org]

• Disability

  "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015". [en.wikipedia.org]

• Precocious Puberty

  However, like sex cord tumors, they can cause ovarian torsion or hemorrhage and, in children, isosexual precocious puberty. [en.wikipedia.org]

• Virilization

  Sertoli-Leydig cell tumors cause virilization and excessive hair growth due to the production of testosterone and androstenedione, which can also cause Cushing's syndrome in rare cases. [en.wikipedia.org]

• Abdominal Pain

  If you have any of the following symptoms, especially if you have them for more than 12 days per month, contact your ob-gyn or other health care professional: Bloating or an increase in abdominal size Pelvic or abdominal pain Difficulty eating or feeling [acog.org]

  The typical symptoms of an LMP tumor can include abdominal distension or pelvic pain. [en.wikipedia.org]

• Irregular Menstruation

  These tumors cause abnormalities in menstruation ( excessive bleeding, infrequent menstruation, or no menstruation ) or postmenopausal bleeding. [en.wikipedia.org]

[…] to determine the extent of its spread (which is a form of tumor staging ). [16] Risk scoring [ edit ] A widely recognized method of estimating the risk of malignant ovarian cancer is the risk of malignancy index (RMI), calculated based on an initial workup [en.wikipedia.org]

Fred Hutch researchers continue to refine these treatments and develop new targeted therapies and immunotherapies for the disease. [fredhutch.org]

A treatment plan is developed. [53] Treatment usually involves surgery and chemotherapy, and sometimes radiotherapy, regardless of the subtype of ovarian cancer. [45] [54] Surgical treatment may be sufficient for well-differentiated malignant tumors and [en.wikipedia.org]

Common Uterine Conditions, Options for Treatment. Agency for Healthcare Research and Quality [On-line information]. Available online at http://www.ahrq.gov/consumer/uterine1.htm#sec1. Cancer Screening Guidelines. [labtestsonline.it]

Ovarian carcinomas are a heterogeneous group of lesions with specific morphology, biology, response to treatment, and behavior. The correct diagnosis is based on histopathologic examination of the specimen. [ncbi.nlm.nih.gov]

[…] genes associated with favourable prognosis. [proteinatlas.org]

Most tumors are stage I, and patients exhibit an excellent prognosis with a 5-year survival rate of 88%. When extra-ovarian, the prognosis is similar to other ovarian carcinomas. [ncbi.nlm.nih.gov]

"Age at menarche and risk of ovarian cancer: a meta-analysis of epidemiological studies". International Journal of Cancer. 132 (12): 2894–2900. doi : 10.1002/ijc.27952. ISSN 0020-7136. PMC 3806278. PMID 23175139. ^ Manson JE, Bassuk SS (2012). [en.wikipedia.org]

[…] though research is still ongoing in this area. [24] Higher caffeine intake and consumption of more than two cups of tea a day have both been associated with lower ovarian cancer risk. [21] Smoking tobacco is protective for sex cord-stromal tumors. [22] Pathophysiology [en.wikipedia.org]

Preventive Services Task Force Reaffirmation Recommendation Statement. USPSTF [On-line information]. Available online at http://www.uspreventiveservicestaskforce.org/uspstf12/ovarian/ovarartaddend.htm. [labtestsonline.it]

Archived from the original on 2016-09-19. ^ a b c d "Ovarian Cancer Prevention (PDQ®)". NCI. December 6, 2013. Archived from the original on 6 July 2014. Retrieved 1 July 2014. ^ a b c "Ovarian Cancer Prevention (PDQ®)". NCI. 2014-06-20. [en.wikipedia.org]