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Ovarian Dysfunction

Unspecified Ovarian Dysfunction


Presentation

  • Moreover, the elder sister initially presented with resistant ovary syndrome and thereafter true premature menopause, while the younger one presented with resistant ovary syndrome.[ncbi.nlm.nih.gov]
Infertility
  • We conclude that ovarian biopsies do not provide additional information to the clinical-hormonal criteria previously established in the workup of infertile patients.[ncbi.nlm.nih.gov]
Precocious Puberty
  • Specific gene mutations causing delayed puberty and/or ovarian failure, and heterosexual or isosexual precocious puberty have recently been described.[ncbi.nlm.nih.gov]
  • puberty E30.8 Other disorders of puberty E30.9 Disorder of puberty, unspecified Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.[icd10data.com]
Italian
  • CASE PRESENTATION: We describe the coexistence in a large Italian kindred of Fragile X syndrome and familial POF in females with ovarian dysfunctions who carried normal or expanded FMR1 alleles.[ncbi.nlm.nih.gov]
Fishing
  • Among the developmental anomalies observed in amphibia and fish are a number of gonadal aberrations, often occurring in otherwise normal specimens.[ncbi.nlm.nih.gov]
Virilization
  • Thus, our preliminary study reviews our experience to date and suggests that NP-59 scintigraphy may be used to localize both tumorous and nontumorous ovarian dysfunction in states of HA and virilization.[ncbi.nlm.nih.gov]
Nausea
  • Nausea and constipation were more prevalent in the liraglutide group. Liraglutide improved markers of ovarian function in overweight women with PCOS, and might be a possible intervention. Copyright 2017 Reproductive Healthcare Ltd.[ncbi.nlm.nih.gov]
  • Adverse effects of clomiphene include vasomotor flushes (10%), abdominal distention (6%), breast tenderness (2%), nausea (3%), visual symptoms (1 to 2%), and headaches (1 to 2%).[merckmanuals.com]
Osteopenia
  • Osteopenia before adjuvant therapy predicted an increased risk for osteoporosis.[ncbi.nlm.nih.gov]
Hyperactivity
  • […] factors [like HA (hyaluronan), TSG-6 (TNF-α-stimulated gene/protein 6), PTX-3 (pentraxin-3), HABP1 (hyaluronan binding protein 1), MMP2 (matrix metalloproteinase), MT1-MMP (membrane type 1-matrix metalloproteinase) and COX2 (Cyclooxygenase-2)] along with hyperactivities[ncbi.nlm.nih.gov]
  • Hypo-reactive Medical condition History of Infections Common Occasional Chronic Fatigue Yes Yes Orthostatic Hypotension Frequent No Blood Sugar Tendency toward hypoglycemia Normal to hyperglycemia Heart Palpitations Frequent No GI Function Irritable or hyperactive[drlam.com]

Workup

  • We conclude that ovarian biopsies do not provide additional information to the clinical-hormonal criteria previously established in the workup of infertile patients.[ncbi.nlm.nih.gov]
  • The initial workup of ovulatory dysfunction includes an evaluation of thyroid function and a measurement of the pituitary hormone prolactin.[txfertility.com]
  • Both prolactin and thyroid hormones are measured in the initial fertility workup.[nycivf.org]
  • Despite multiple referrals to specialists and extensive workups, the end result is often the same – frustrated clinicians and disappointed patients. The abandoned patient is ultimately left to self-navigate.[drlam.com]

Treatment

  • They all showed a rapid decline in AMH after 3 months of treatment, regardless of AMH at diagnosis, age, menarche, or treatment given.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis is generally good Who gets Ovarian Hypofunction? (Age and Sex Distribution) Ovarian Hypofunction affects nearly 1% of all female population of childbearing age, before the age of 40 years.[dovemed.com]

Etiology

  • However a young woman, who presented a severe ovarian failure with early onset, carried normal FMR1 alleles ( CONCLUSION: Our case study represents a helpful observation and will provide familial cases with heterogeneous etiology that could be further[ncbi.nlm.nih.gov]
  • Regardless of the etiology, patients with primary ovarian insufficiency are estrogen deficient.[acog.org]
  • (Etiology) Majority of the time, the cause of Ovarian Hypofunction is unknown.[dovemed.com]

Epidemiology

  • RESULTS: Epidemiological and clinical studies indicate that common premenopausal reproductive abnormalities (manifested along a continuum from mild subclinical alterations to complete suppression) are associated with increased risk of CHD.[ncbi.nlm.nih.gov]
  • Epidemiological and clinical studies indicate that common premenopausal reproductive abnormalities (manifested along a continuum from mild subclinical alterations to complete suppression) are associated with increased risk of CHD.[journals.lww.com]
  • It also avoids the first-pass effect in the liver. [34] Epidemiology [ edit ] It has been estimated that POF affects 1% of the female population. [35] History [ edit ] Fuller Albright et al. in 1942 first reported a syndrome in young women characterized[en.wikipedia.org]
  • Epidemiology Frequency United States POI/POF occurs in approximately 1% of women. [7] The estimated incidence in the United States is 1 case per 1000 women by age 30, 1 case per 250 women by age 35 and 1 case per 100 women by age 40.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Advances in molecular genetics have allowed new insights into the pathophysiology of ovarian disorders.[ncbi.nlm.nih.gov]
  • Pathophysiology POI is, in reality, a continuum of disorders. Dividing the continuum of ovarian insufficiency into 4 clinical states is the authors' preferred method to facilitate explanation. These states are not permanent.[emedicine.medscape.com]

Prevention

  • Histone deacetylases (HDACs) prevent the relaxation of chromatin, and positively or negatively regulate transcription.[ncbi.nlm.nih.gov]
  • These observations suggest that efforts to prevent coronary heart disease in postmenopausal women should begin during the premenopausal years.[journals.lww.com]
  • Presently, Ovarian Hypofunction is a condition that cannot be prevented in most cases.[dovemed.com]
  • Can primary ovarian insufficiency be prevented? At this time, there is no way to prevent primary ovarian insufficiency. But you can take steps to protect your overall health.[northshore.org]
  • Fortunately there are many things you can do naturally to prevent premature ovarian failure and get pregnant even if you had been diagnosed with poor egg quality due to follicles depletion.[natural-health-for-fertility.com]

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