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Ovarian Dysfunction

Unspecified Ovarian Dysfunction


Presentation

  • Moreover, the elder sister initially presented with resistant ovary syndrome and thereafter true premature menopause, while the younger one presented with resistant ovary syndrome.[ncbi.nlm.nih.gov]
  • CASE PRESENTATION: We describe the coexistence in a large Italian kindred of Fragile X syndrome and familial POF in females with ovarian dysfunctions who carried normal or expanded FMR1 alleles.[ncbi.nlm.nih.gov]
  • Patients with POF presented significantly lower counts of primordial, primary, and secondary follicles. No significant differences were found in the other groups.[ncbi.nlm.nih.gov]
  • Abstract The clinical use of bromocriptine (2.5 mg twice daily) was investigated in 40 women attending an infertility clinic and presenting with secondary amenorrhoea (18) or with ovarian dysfunction (22) which had failed to respond to anti-oestrogen[ncbi.nlm.nih.gov]
  • The authors discuss the problem of ovarian dysfunction after oncological treatment and present the possible strategies for saving the reproductive function of ovaries, including both invasive and pharmacological approaches.[ncbi.nlm.nih.gov]
Infertility
  • We conclude that ovarian biopsies do not provide additional information to the clinical-hormonal criteria previously established in the workup of infertile patients.[ncbi.nlm.nih.gov]
  • Abstract Significant association between endometriosis, including minor endometriosis, and infertility (or strictly subfertility) is shown by prevalence studies, but a causal relationship has not been established.[ncbi.nlm.nih.gov]
  • Thirty-two infertile PCOS women and 147 infertile women with tubal blockage were recruited. PCOS women were divided into the hyperandrogenism (HA) PCOS group (n   13) and nonhyperandrogenism (N-HA) PCOS group (n   19).[ncbi.nlm.nih.gov]
  • Abstract Post-partum uterine disorders and reproductive tract infections cause ovarian dysfunction and infertility. Histone deacetylases (HDACs) prevent the relaxation of chromatin, and positively or negatively regulate transcription.[ncbi.nlm.nih.gov]
  • All families affected by blepharophimosis should be counselled about the high incidence of ovarian dysfunction and female infertility, at least in one form of the syndrome.[ncbi.nlm.nih.gov]
Fishing
  • Among the developmental anomalies observed in amphibia and fish are a number of gonadal aberrations, often occurring in otherwise normal specimens.[ncbi.nlm.nih.gov]
Virilization
  • Thus, our preliminary study reviews our experience to date and suggests that NP-59 scintigraphy may be used to localize both tumorous and nontumorous ovarian dysfunction in states of HA and virilization.[ncbi.nlm.nih.gov]
Constipation
  • Nausea and constipation were more prevalent in the liraglutide group. Liraglutide improved markers of ovarian function in overweight women with PCOS, and might be a possible intervention. Copyright 2017 Reproductive Healthcare Ltd.[ncbi.nlm.nih.gov]
Osteopenia
  • Osteopenia before adjuvant therapy predicted an increased risk for osteoporosis.[ncbi.nlm.nih.gov]

Workup

  • We conclude that ovarian biopsies do not provide additional information to the clinical-hormonal criteria previously established in the workup of infertile patients.[ncbi.nlm.nih.gov]
  • The initial workup of ovulatory dysfunction includes an evaluation of thyroid function and a measurement of the pituitary hormone prolactin.[txfertility.com]
  • Both prolactin and thyroid hormones are measured in the initial fertility workup.[nycivf.org]
Testosterone Decreased
  • In the liraglutide group, SHBG increased by 7.4 nmol/L (95% CI 4.1 to 10.7) and free testosterone decreased by 0.005 nmol/L (95% CI -0.009 to -0.001). Ovarian volume decreased by -1.6 ml (95% CI -3.3 to 0.1) with liraglutide versus placebo.[ncbi.nlm.nih.gov]

Treatment

  • They all showed a rapid decline in AMH after 3 months of treatment, regardless of AMH at diagnosis, age, menarche, or treatment given.[ncbi.nlm.nih.gov]
  • The results confirmed that bromocriptine is effective in the treatment of hyperprolactinaemic states whether there is amenorrhoea or not.[ncbi.nlm.nih.gov]
  • A fertility preservation is an important issue in oncological treatment, where there is a need for balancing between radicality and the preservation of function of reproductive organs.[ncbi.nlm.nih.gov]
  • Serum PR;, follicle-stimulating hormone, and luteinizing hormone were measured for a preceding control cycle and during the cycle following Clomid treatment in the 12 patients.[ncbi.nlm.nih.gov]

Etiology

  • However a young woman, who presented a severe ovarian failure with early onset, carried normal FMR1 alleles ( CONCLUSION: Our case study represents a helpful observation and will provide familial cases with heterogeneous etiology that could be further[ncbi.nlm.nih.gov]
  • CT and/or ultrasound studies failed to demonstrate an abnormality in the pelvis suggesting excessive peripheral conversion or abnormal end organ sensitivity of androgen precursors as potential etiologies of their HA.[ncbi.nlm.nih.gov]
  • BACKGROUND/AIMS: To investigate the etiology of hypogonadism in women with Prader-Willi Syndrome (PWS). METHODS: Ten women aged 23 /- 5.5 years with PWS and 10 age- and BMI-matched controls were included.[ncbi.nlm.nih.gov]
  • Regardless of the etiology, patients with primary ovarian insufficiency are estrogen deficient.[acog.org]
  • Etiology Chronic ovulatory dysfunction in premenopausal women is most commonly caused by But it has many other causes, including Hyperprolactinemia Hypothalamic dysfunction (eg, functional hypothalamic amenorrhea) Symptoms and Signs Ovulatory dysfunction[merckmanuals.com]

Epidemiology

  • RESULTS: Epidemiological and clinical studies indicate that common premenopausal reproductive abnormalities (manifested along a continuum from mild subclinical alterations to complete suppression) are associated with increased risk of CHD.[ncbi.nlm.nih.gov]
  • Epidemiological and clinical studies indicate that common premenopausal reproductive abnormalities (manifested along a continuum from mild subclinical alterations to complete suppression) are associated with increased risk of CHD.[journals.lww.com]
  • STUDY DESIGN: This study analyzed AMH and INSL3 levels in forty healthy eumenorrheic late adolescent females (aged 16-19 ys), selected from a cross-sectional epidemiological study performed on the prevalence of hyperandrogenic states.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Advances in molecular genetics have allowed new insights into the pathophysiology of ovarian disorders.[ncbi.nlm.nih.gov]
  • Disrupted tissue remodeling machinery can result into pathophysiologies like atretic follicular cysts formation in polycystic ovary syndrome (PCOS).[ncbi.nlm.nih.gov]
  • Abstract A pathophysiology paradigm shift has emerged with the discovery that polycystic ovary syndrome (PCOS) is a proinflammatory state.[thieme-connect.com]

Prevention

  • Histone deacetylases (HDACs) prevent the relaxation of chromatin, and positively or negatively regulate transcription.[ncbi.nlm.nih.gov]
  • These observations suggest that efforts to prevent coronary heart disease in postmenopausal women should begin during the premenopausal years.[journals.lww.com]
  • Can primary ovarian insufficiency be prevented? At this time, there is no way to prevent primary ovarian insufficiency. But you can take steps to protect your overall health.[northshore.org]
  • Fortunately there are many things you can do naturally to prevent premature ovarian failure and get pregnant even if you had been diagnosed with poor egg quality due to follicles depletion.[natural-health-for-fertility.com]
  • The reason PCOS prevents ovulation is not completely clear. One theory suggests that the high levels of LH found in women with PCOS contribute to ovulatory dysfunction.[womenlivingnaturally.com]

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