Presentation
(Oxf) VL - 24 IS - 3 N2 - A 5-year-old girl with the McCune-Albright syndrome presented with precocious puberty secondary to autonomously functioning ovarian cysts, followed by true central puberty. [wwww.unboundmedicine.com]
Three girls presented recurrent autonomous ovarian cysts ( Table 2 ) and are described below in more detail. Patient No. 2 presented three episodes of precocious pseudopuberty at the age of 6, 7, and 7.7 years. [hormones.gr]
Abstract Diabetic women present an elevated incidence of mestrual disorders often associated with partial gonadotropic insufficiency with reduced LH, E2 and ovarian androgen production. [nature.com]
In females hyperprolactinaemia usually presents with amenorrhoea and in males with lack of libido. [slideshare.net]
[…] predominate (see Presentation). [emedicine.medscape.com]
Workup
Diagnosis is challenging, but an initial workup includes cortisol and dexamethasone suppression testing. [arupconsult.com]
Diagnostic imaging modalities that may be considered include plain radiography, ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide bone scanning (as clinically indicated) (see Workup). [emedicine.medscape.com]
Treatment
The close examination carried out during fertility treatment results in early detection and treatment of ectopic pregnancies. Miscarriage : 10 - 15 % of all pregnancies end in miscarriage. [vivaneo-ivf.com]
Regardless of the etiology, there currently is no effective treatment that will be likely to result in a pregnancy (with her own eggs) for premature ovarian failure. Egg donation is a highly successful treatment (see below). [advancedfertility.com]
Treatment may be medical, surgical, or by irradiation, depending on the nature of the disorder. See Ch. 25,, for fuller treatment of ovarian and other disorders affecting women. [faqs.org]
While treatment of central precocious puberty usually requires a GnRH agonist, in general no treatment is necessary for precocious pseudopuberty due to autonomous ovarian cysts. [hormones.gr]
Treatment Treatment for ovarian cancer typically involves both surgery and chemotherapy. The surgery will involve removing the ovaries, fallopian tubes, uterus, and possibly surrounding lymph nodes. [fortherecordmag.com]
Prognosis
The prognosis is generally good Who gets Ovarian Hypofunction? (Age and Sex Distribution) Ovarian Hypofunction affects nearly 1% of all female population of childbearing age, before the age of 40 years. [dovemed.com]
Thus, the prognosis varies according to the manifestations of MAS. With precocious puberty, the prognosis depends on the duration of premature estrogen exposure. [emedicine.medscape.com]
Therefore, the prognosis is not as favorable since it’s more difficult to treat ovarian cancer in its later stages. [fortherecordmag.com]
Prognosis Morbidity is most commonly related to complications of polyostotic fibrous dysplasia and the need for orthopaedic intervention. [atlasgeneticsoncology.org]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
The first goal of this study is to identify any possible contributions of the BAH phenotypes and genotypes to the pathophysiology of PCOS, a yet unknown factor in the etiology of this multifaceted disorder. [clinicaltrials.gov]
Regardless of the etiology, patients with primary ovarian insufficiency are estrogen deficient. [acog.org]
Regardless of the etiology, there currently is no effective treatment that will be likely to result in a pregnancy (with her own eggs) for premature ovarian failure. Egg donation is a highly successful treatment (see below). [advancedfertility.com]
(Etiology) Majority of the time, the cause of Ovarian Hypofunction is unknown. [dovemed.com]
Epidemiology
Epidemiology United States and international statistics The exact incidence of MAS in the United States and internationally is unknown, but its prevalence is probably between 1 case in 100,000 population and 1 case in 1 million population, rendering it [emedicine.medscape.com]
Pathophysiology
[…] biochemistry of nutrition 180 Nutritional disorders and their management 200 Clinical biochemistry of the gastrointestinal tract 214 Assessment of hepatic function and investigation of jaundice 231 Acute and chronic liver disease 250 Glucose metabolism and the pathophysiology [books.google.de]
The first goal of this study is to identify any possible contributions of the BAH phenotypes and genotypes to the pathophysiology of PCOS, a yet unknown factor in the etiology of this multifaceted disorder. [clinicaltrials.gov]
The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. J Clin Endocrinol Metab. 2008 Jun. 93(6):2383-9. [Medline]. [Full Text]. Lietman SA, Ding C, Levine MA. [emedicine.medscape.com]
Gsalpha expression from the maternal allele will result in pathophysiological abnormality in tissues where that allele is expressed, but paternally expressed GNAS alleles may also result in endocrine dysfunction. [atlasgeneticsoncology.org]
Prevention
Presently, Ovarian Hypofunction is a condition that cannot be prevented in most cases. [dovemed.com]
Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.com]
In such cases, a further loss of height potential can be prevented by treatment with a GnRH agonist, but further relapses of the autonomous ovarian cyst cannot be prevented by such intervention. REFERENCES 1. [hormones.gr]
Treatment Estrogen therapy often helps relieve menopausal symptoms and prevents bone loss. However, it will not increase your chances of becoming pregnant. Less than 1 in 10 women with ovarian hypofunction will be able to get pregnant. [coordinatedhealth.com]
Estrogen therapy often helps relieve menopausal symptoms and prevents bone loss. However, it will not increase your chances of becoming pregnant. Fewer than 1 in 10 women with this condition will be able to get pregnant. [medlineplus.gov]