The charts of 60 patients who presented to the emergency room with the diagnosis of epistaxis and who required medical management were reviewed. Sixty-five percent of these patients were successfully managed with oxymetazoline as their sole therapy. [ncbi.nlm.nih.gov]

• Gangrene

  Development of gangrene necessitated a disarticulation at the wrist joint. Diagnosis, complications, and therapeutic measures of acute hand ischemia secondary to intra-arterial drug injection are discussed. [ncbi.nlm.nih.gov]

• Hypertension

  Severe hypertension with reflex bradycardia progressed to sinus arrest and was successfully treated with alropine and cardiopulmonary resuscitation. Decreasing the dose of oxymetazoline and pretreatment with an anticholinergic is recommended. [ncbi.nlm.nih.gov]

  Category: Decongestant Description: Topical decongestant Indications: Nasal congestion Precautions: Pregnancy category C Children Hyperthyroidism, heart disease Hypertension, diabetes mellitus Adverse Reactions (Side Effects): CNS: dizziness, headache [medicalcorps.org]

  Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye. Precautions Information Not Available Special Precautions Pregnancy, lactation. [drugsupdate.com]

  Hyperthyroidism, diabetes, use of a monoamine oxidase inhibitor within 14 days, or known hypersensitivity to this drug prohibits its use. adverse effects Among the more serious adverse effects are rebound congestion, central nervous system stimulation, hypertension [medical-dictionary.thefreedictionary.com]

• Hypotension

  Advise patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension/hypotension to seek immediate medical care if their condition worsens. [prnewswire.com]

  Gradman Bradycardia, hypotension, and near‐syncope associated with afrin (oxymetazoline) nasal spray N Engl J Med, 309 (1983), pp. 73 [2] A. Khan, N. [elsevier.pt]

  Because of his urinary retention, he was placed on the 1 antagonist tamsulosin but he could not tolerate it because of worsening of orthostatic hypotension. [web.archive.org]

  oxymetazoline, naphazoline, tetrahydrozoline) in children has resulted in serious adverse events requiring hospitalization, including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, [drugs.com]

• Stupor

  […] naphazoline, tetrahydrozoline) in children has resulted in serious adverse events requiring hospitalization, including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor [drugs.com]

  Fifty-three cases reported hospitalization due to symptoms including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor, hypothermia, drooling, and coma. [fda.gov]

• Gram-Positive Bacteria

  It is considered important in nasal defence as it enzymatically hydrolyses peptidoglycan bonds in bacterial cell walls and has specific activity against Gram-positive bacteria in vitro. [ncbi.nlm.nih.gov]

• Sinus Arrest

  Severe hypertension with reflex bradycardia progressed to sinus arrest and was successfully treated with alropine and cardiopulmonary resuscitation. Decreasing the dose of oxymetazoline and pretreatment with an anticholinergic is recommended. [ncbi.nlm.nih.gov]

NAR and VAS measurements were also made following withdrawal of treatment on Days 8 and 9. [ncbi.nlm.nih.gov]

Areas covered : Current treatment options for the treatment of rosacea include metronidazole, azelaic acid, sodium sulfacetamide-sulfur, and brimonidine. [doi.org]

[…] appearance-related distress.6 Current evidence identifies ptosis as a common disorder of the eyelid, particularly among elderly patients.7-9 Ptosis is broadly categorized as either congenital or acquired,10 with the acquired form classified based on underlying etiology [jamanetwork.com]

The pathophysiology of this syndrome is discussed in light of locus ceruleus neuropharmacology. This may be the first report of such a withdrawal syndrome. [ncbi.nlm.nih.gov]

Szenborn, Pathophysiology of Clinical Symptoms in Acute Viral Respiratory Tract Infections, Pulmonary Infection, 10.1007/5584_2015_110, (25-38), (2015). [doi.org]

OBJECTIVE: To compare the effectiveness of ciprofloxacin and oxymetazoline solutions instilled after tympanostomy tube placement in the prevention of postoperative otorrhea and tube occlusion. STUDY DESIGN: Prospective cross-sectional series. [ncbi.nlm.nih.gov]

Efficacy of pseudoephedrine for the prevention of barotrauma during air travel. Ann Emerg Med. 1994; 23:1324-7. 101. Jones JS, Sheffield W, White LJ et al. [drugs.com]

[…] and oxymetazoline was 86% effective in preventing bleeding during this procedure. [intranasal.net]