Development of gangrene necessitated a disarticulation at the wrist joint. Diagnosis, complications, and therapeutic measures of acute hand ischemia secondary to intra-arterial drug injection are discussed. [ncbi.nlm.nih.gov]

This resulted in severe burning pain, and cyanotic, cold, and pulseless hand, suggestive of acute ischemia. [ncbi.nlm.nih.gov]

Severe hypertension with reflex bradycardia progressed to sinus arrest and was successfully treated with alropine and cardiopulmonary resuscitation. Decreasing the dose of oxymetazoline and pretreatment with an anticholinergic is recommended. [ncbi.nlm.nih.gov]

Category: Decongestant Description: Topical decongestant Indications: Nasal congestion Precautions: Pregnancy category C Children Hyperthyroidism, heart disease Hypertension, diabetes mellitus Adverse Reactions (Side Effects): CNS: dizziness, headache [medicalcorps.org]

Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye. Precautions Information Not Available Special Precautions Pregnancy, lactation. [drugsupdate.com]

Hyperthyroidism, diabetes, use of a monoamine oxidase inhibitor within 14 days, or known hypersensitivity to this drug prohibits its use. adverse effects Among the more serious adverse effects are rebound congestion, central nervous system stimulation, hypertension [medical-dictionary.thefreedictionary.com]

Advise patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension/hypotension to seek immediate medical care if their condition worsens. [prnewswire.com]

Gradman Bradycardia, hypotension, and near‐syncope associated with afrin (oxymetazoline) nasal spray N Engl J Med, 309 (1983), pp. 73 [2] A. Khan, N. [elsevier.pt]

Because of his urinary retention, he was placed on the 1 antagonist tamsulosin but he could not tolerate it because of worsening of orthostatic hypotension. [web.archive.org]

oxymetazoline, naphazoline, tetrahydrozoline) in children has resulted in serious adverse events requiring hospitalization, including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, [drugs.com]

[…] naphazoline, tetrahydrozoline) in children has resulted in serious adverse events requiring hospitalization, including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor [drugs.com]

Fifty-three cases reported hospitalization due to symptoms including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor, hypothermia, drooling, and coma. [fda.gov]

It is considered important in nasal defence as it enzymatically hydrolyses peptidoglycan bonds in bacterial cell walls and has specific activity against Gram-positive bacteria in vitro. [ncbi.nlm.nih.gov]

Severe hypertension with reflex bradycardia progressed to sinus arrest and was successfully treated with alropine and cardiopulmonary resuscitation. Decreasing the dose of oxymetazoline and pretreatment with an anticholinergic is recommended. [ncbi.nlm.nih.gov]