We report the case of a 61-year-old woman who presented with a long history of multiple symptomatic hyperkeratotic papules on the palms and soles. [mdedge.com]

The present study was conducted on 12 unrelated Chinese patients who were clinically predicted to suffer from NPPK. [ncbi.nlm.nih.gov]

Gene Identification Often, the clinical presentation is not as straight forward as the texts present. Clinical evaluation can present with diffuse as well as punctuate keratodermas and associated nail dystrophy. [faoj.org]

Here, we present another case of 2 siblings with possible Nagashima-type PPK. [karger.com]

Furthermore, indexed unaffected parents in the present cohort were all heterozygous carriers. [spandidos-publications.com]

[…] sporadically from unaffected parent carriers, and autosomal dominant PPK can also occur sporadically due to a new mutation in an affected person (a de novo mutation). [4] Histopathology of a biopsy from affected skin should be part of the diagnostic workup [rarediseases.info.nih.gov]

A 48-year-old woman developed palmoplantar hyperkeratosis during treatment with imatinib (400mg/day) for treatment of chronic myeloid leukemia. [ncbi.nlm.nih.gov]

Treatment Treatment regimes are based on surgical techniques, medications and ancillary treatments designed to decrease painful keratosis. Surgical debridement or paring of keratosis is effective, but only temporary. [faoj.org]

Endoscopic thoracic sympathectomy is an effective and long-term treatment for palmar hyperhidrosis. [doi.org]

This syndrome requires a multidisciplinary team for treatment and control and the prognosis is still poor. [clinicadavilla.com.br]

Diagnosis - Keratosis palmoplantaris adenocarcinoma of the colon * Home Colorectal Cancer Tests * Home Fecal Occult Bleeding Tests Prognosis - Keratosis palmoplantaris adenocarcinoma of the colon Not supplied. [checkorphan.org]

Prognosis The prognosis of tylosis with oesophageal cancer is difficult to determine due to the limited number of affected individuals. [ojrd.biomedcentral.com]

In terms of treatment, the most successful results occur when the underlying etiology is diagnosed and treated. [ncbi.nlm.nih.gov]

The third volume of Recent Advances in Dermatology has been fully revised to bring clinicians and trainees fully up to date with the latest advances in dermatology, with emphasis on etiology, clinical features, diagnosis and treatment. [books.google.de]

They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]

[…] mechanisms of one of the most toxic minerals in the world • Helps readers understand potential health effects of arsenic, using population studies, mammalian and invertebrate models, and pharmacokinetic and toxicokinetic models • Discusses outcomes, epidemiology [books.google.de]

Disorder Synonyms PPK Column* ICD-9 Selected Epidemiologic Features Genetic Cause Syndromic Associations Distinguishing features Age of onset (for disorder manifistation) Erythema Transgrediens Other Epidermal Features** Systemic Features*** Relevant [dermatologyadvisor.com]

Epidemiology The condition is rare in Europe but more common in the East [ 6 ]. It occurs much more commonly in smokers and ex-smokers. It may run in families and rarely occurs in childhood. [patient.info]

Recent perspectives on the global epidemiology of childhood eczema. Allergol Immunopathol (Madr). 2011;39:174-182. Bieber T. Mechanisms of disease: atopic dermatitis. New Engl J Med. 2008;358:1483. Kurian A, Barankin B. [dermatology.exeltisusa.com]

Genetic epidemiology of breast cancer and associated cancers in high risk families. I. Segregation analysis. JNCI 71, 455–461 (1983). 17 Hall, J.M., Lee, M.K., Morrow, J., Anderson, L. & King, M.-C. [nature.com]

Its pathophysiology is still unclear. However the combination of impairment of genetic and environmental factors is most likely. The transmission is often autosomal dominant, rarely autosomal recessive. [ 5, 6, 7 ]. [pubs.sciepub.com]

[…] epidermolytic leukoplakia Terminology Other names: Epidermolytic ichthyosis Bullous congenital ichthyosiform erythroderma Bullous ichthysosis Bullous erythroderma ichthyosiformis congenita of Brocq Disorder of cornification type 3 Vorner's syndrome Pathophysiology [pathologyoutlines.com]

Decubitus ulcers: pathophysiology and primary prevention. Dtsch Arztebl Int. 2010;107:371-382. Beers MH, Berkow, R, eds. The Merck Manual of Diagnosis and Therapy. 17th ed. Whitehouse Station, NJ: Merck & Company, Inc; 1999. [dermatology.exeltisusa.com]

Oral hygiene : Regular tooth care to prevent cavities is recommended. [nutritionhouse.com]

Prevention - Keratosis palmoplantaris adenocarcinoma of the colon Not supplied. [checkorphan.org]

Currently, Diffuse Hereditary Palmoplantar Keratoderma is a genetic disorder that cannot be prevented. [dovemed.com]

Lobmann, R, Kayser, R, Kasten, G: Effects of preventative footwear on foot pressure as determined by pedobarography in diabetic patients: a prospective study. Diabet. Med. 18: 314 – 319, 2001. Google Scholar | Crossref | Medline | ISI 6. [dx.doi.org]