Pancoast presented two papers in 1924 and 1932 and the tumour became known as Pancoast Tumour. In his papers, Pancoast describes the clinical presentation of three cases. [raynersmale.com]

Left apical opacity seen on single-view anteroposterior chest radiograph in a 32-year-old male smoker with primary lung signet ring cell carcinoma presenting as a cavitary Pancoast tumor. Figure 1. [jaoa.org]

This case report highlights the clinical presentation of Pancoast tumor and emphasizes the importance of its inclusion in the differential diagnosis of patients presenting with persistent pain in the neck and shoulder. [nepjol.info]

Drooping of right shoulder and hollowing of right supra and infraclavicular region present. Chest movements and expansion decreased on right side. Scoliosis with concavity to right side present. 6. [slideshare.net]

The left 2nd and 3rd ribs (black arrow) are destroyed and therefore missing, whereas they are normally present on the right (white arrows). [learningradiology.com]

• Fever

  Pancoast tumors are named for Henry Pancoast, a US radiologist, who described them in 1924 and 1932. [1] Signs and symptoms [ edit ] Aside from cancer general symptoms such as malaise, fever, weight loss and fatigue, Pancoast tumor can include a complete [en.wikipedia.org]

  A review of his systems was positive for hoarseness and lowgrade intermittent fever without any shortness of breath or cough. [jmedicalcasereports.biomedcentral.com]

  There was no history of fever, weight loss, and anorexia. She was normotensive and non-diabetic. There was no past history of the tuberculosis. [lungindia.com]

• Pseudotumor

  Inflammatory pseudotumor (plasma cell granuloma), mycotic subclavian artery aneurysm, and carotid pseudoaneurysm in a child (caused by a hydatid cyst) have been reported. [aboutcancer.com]

• Wound Infection

  Surgical complications Thoracic complications (I) Prolonged air leakage, (II) wound infection, and (III) wound dehiscence are frequent surgical complications. [ncbi.nlm.nih.gov]

• Cough

  These tumors are less likely than other lung cancers, due to their unique location, to cause the symptoms of cough and chest pain commonly associated with lung cancer. [emedicinehealth.com]

  When to see a doctor It is important for people to see a doctor if they develop any of the symptoms of Pancoast syndrome, or any other symptoms associated with lung cancer, such as coughing or shortness of breath. [medicalnewstoday.com]

  The tumor can also compress the recurrent laryngeal nerve and from this a hoarse voice and "bovine" (non-explosive) cough may occur. [en.wikipedia.org]

  The patient is immobilized the first post op day with attention to chest Physiotherapy and bronchoscopic suctioning may be necessary to clear secretions in patients with ineffective cough [6]. [physio-pedia.com]

  A review of his systems was positive for hoarseness and lowgrade intermittent fever without any shortness of breath or cough. [jmedicalcasereports.biomedcentral.com]

• Jugular Venous Distention

  Physical examination revealed ptosis and jugular venous distention with normal neurological findings and normal shoulder movements. His back was not painful with palpation either. [academic.oup.com]

• Anisocoria

  On physical exam, anisocoria was noted with the right pupil being smaller than the left pupil. [swjpcc.com]

• Hand Muscle Weakness

  Muscle weakness, atrophy and parasthesia Horner’s syndrome in up to 50% due to invasion of the superior cervical sympathetic chain and stellate ganglion Ptosis Miosis Anhidrosis Superior vena caval obstruction Phrenic and recurrent laryngeal nerve involvement [learningradiology.com]

  Neurological complications (I) Intrinsic hand muscle weakness (Klumpke-Déjérine syndrome) can be caused by C8 root division; while the division of T1 root affects the neural system less significantly. [ncbi.nlm.nih.gov]

• Decreased Sweating

  sweating) (Arcasoy & jett, 1997; Manenti, et al., 2013). [raynersmale.com]

• Distractibility

  The head of the rib is disarticulated from the transverse process by dividing the costotransverse ligaments and, with gentle pressure, using a periosteal elevator to distract the rib anteriorly away from its transverse process attachments. ( Figure 9 [ctsnet.org]

[…] artery), or MRI  Additional MRI is mandatory if the workup suggests tumor encroachment into the intervertebral foramina to rule out invasion of the extradural space. 10. [de.slideshare.net]

WORKUP LABORATORY STUDIES : CBC BUN/ creatinine levels. WBC count Urine analysis. Coagulation profile(PT, aPTT and platelet count). Cross matching. [slideshare.net]

Treatment o Workup: · Typical NSCLC workup: · CT chest and abdomen · CBC, LFTs, electrolytes · Bone scan · [FDG]-PET imaging or mediastinoscopy to evaluate for mediastinal node involvement for triaging patients to operative versus non-operative treatment [vcuthoracicimaging.com]

No alterations were observed in the results of the blood workup, biochemical blood tests or urinalysis. His PPD was nonreactor and testing for acid-fast bacilli in sputum was negative. [scielo.br]

Laboratory Studies The blood workup for patients with Pancoast tumors is not specific, and results are not diagnostic. Lung cancers produce various substances. [emedicine.medscape.com]

• Periostal Elevation

  The head of the rib is disarticulated from the transverse process by dividing the costotransverse ligaments and, with gentle pressure, using a periosteal elevator to distract the rib anteriorly away from its transverse process attachments. ( Figure 9 [ctsnet.org]

• Pleural Adhesions

  (VI) Chest wall resection or pleural adhesion could results in hemothorax or (VII) bleeding. [ncbi.nlm.nih.gov]

Not only can we recommend the most appropriate treatments for each patient’s unique situation, but we can also deliver these treatments with an unparalleled level of expertise. [moffitt.org]

Treatment-related mortality was 4% and 1-yr survival rate was 76%. [erj.ersjournals.com]

Treatment and survival The particular growth features of the Pancoast tumor have affected the treatment regimen since its disclosure. [ncbi.nlm.nih.gov]

Careful patient selection for trimodality treatment, on the basis of staging and comorbidity, is of vital importance in the treatment of Pancoast tumours. [cardiothoracicsurgery.biomedcentral.com]

This treatment shrinks the cancer and reduces symptoms. You can also have other medicines or treatments to control symptoms. After the radiotherapy your doctor might offer you a course of chemotherapy. [cancerresearchuk.org]

Despite advances in management, prognosis remains poor with an overall 5-year survival of only 36%. [radiopaedia.org]

Diagnosis of Pancoast tumor is often late, and misdiagnosis is a common problem that can affect the prognosis. Therefore, Pancoast tumor should always be considered in differential diagnosis of radicular pain of the upper extremity. [jsurgery.bums.ac.ir]

Prognosis A significant improvement in survival from Pancoast tumors has been achieved in the past few decades. [verywellhealth.com]

[…] metastases are contraindications for surgery Preoperative radiation therapy followed by surgical resection is the most common form of treatment Complications Surgical complications include Atelectasis Chest pain Spinal fluid leaks Horner’s syndrome Prognosis [learningradiology.com]

While malignancy is the most common cause, infectious etiologies are an important consideration as well. [swjpcc.com]

Conclusions Here we present a case of Pancoast tumor with myxofibrosarcoma as the underlying etiology. [jmedicalcasereports.biomedcentral.com]

Etiology and Pathophysiology They most frequently present as non–small cell lung cancer (NSCLC). The most common histologic subtype is adenocarcinoma (50–66% of cases), followed by squamous cell and large cell carcinomas. [unboundmedicine.com]

Etiology Non small cell lung carcinoma (NSCLC) is the most common cell type of Pancoast tumor. Squamous cell is usually the most frequent cell type, followed closely by adenocarcinoma, and less frequently, large cell carcinoma. [vcuthoracicimaging.com]

In 1932, Henry Pancoast first described the clinic-radiological features of the thoracic inlet tumors, but he mistakenly thought that it originates from embryonal epithelial rests of fifth brachial cleft. [2] Among malignant etiologies other than lung [lungindia.com]

Epidemiology These tumors represent 3–5% of all lung cancers. The tumor demonstrates a male preponderance and an average age of presentation during the 6th decade of life. [unboundmedicine.com]

Etiology and Pathophysiology They most frequently present as non–small cell lung cancer (NSCLC). The most common histologic subtype is adenocarcinoma (50–66% of cases), followed by squamous cell and large cell carcinomas. [unboundmedicine.com]

Pathophysiology Pancoast tumor is the type of lung cancer that is associated with invasion of the apical chest wall. [wikidoc.org]

PATHOPHYSIOLOGY The mass is an extension of lung cancer. Mostly squamous cell carcinomas or adeno carcinomas. 3-5% are small cell carcinomas. [slideshare.net]

Given the complexity of the pain pathophysiology seen in Pancoast tumors, and the positive results found in a small body of older and more recent research, surgical therapies such as cordotomy should be considered more often and earlier in the illness [oncnursingnews.com]

Prevention The most important preventive measure that can be taken to reduce the risk of developing any lung cancer is to quit smoking. Avoiding exposure to secondhand smoke and materials, such as asbestos and radon also reduces risk. [medicalnewstoday.com]

Preventing Pancoast Tumor The most important preventive step is to avoid using tobacco products. Quitting tobacco also reduces the risk of lung cancer. [webmd.com]

Risk Factors Tobacco use Secondhand smoke Radiation exposure Occupational exposures including asbestos, chromium, nickel, beryllium, arsenic, soot, or tar Industrial air pollution Family history of lung cancer HIV infection General Prevention Avoidance [unboundmedicine.com]

Is It Possible to Prevent Pancoast Tumors? The most important preventive step is to avoid using tobacco products. Quitting tobacco can reduce the risk of lung cancer. For more information, see Cigarette Smoking. [emedicinehealth.com]

[…] ages of 40-60 [7] Male Female [7] Associated Co-morbidities Muscle atrophy [2] Cervical radiculopathy [2] Horner's Syndrome [6] COPD Vertebrae compression [6] Bone cancer Medications Pharmacotherapy goals are to induce remission, reduce morbidity, and prevent [physio-pedia.com]