Presentation
In 22 patients the fistula was into the peritoneal cavity and they presented with pancreatic ascits. In 7 patients the fistula tracked up through the mediastinum into a pleural cavity, and they presented with pancreatic pleural effusions. [ncbi.nlm.nih.gov]
Presentation These patients present with increased abdominal girth, weight loss, variable abdominal pain, and possibly shortness of breath if the fluid compresses the diaphragm or enters transdiaphragmatic channels resulting in concomitant high amylase [slideshare.net]
Entire Body System
- Ascites
RESULTS: Of 10 patients (age range: 13 months-46 years), four patients had only ascites, four had only pleural effusion and two had both ascites and pleural effusion. [ncbi.nlm.nih.gov]
- Weakness
On present admission, she had complaints of dizziness and generalized weakness for 1 month, and 2-3 episodes of vomiting for 2 days. Examination revealed poor general condition, BP 94/70 mmHg, PR 92/min. [japi.org]
It is characterized, in part, by arthritis, skin rash, weakness, and fatigue. Ultrasonography — A test using sound waves to measure blood flow. Gel is applied to a hand-held transducer that is pressed against the patient's body. [encyclopedia.com]
Symptoms may include weakness or dizziness, chills, muscle spasms, or diarrhea. Staging of Pancreatic Cancer Staging of cancer is a standardized way to classify a tumour based on its size, whether it has spread, and where it has spread. [craigscause.ca]
When they drain it, it takes SO much from them, they look very weak and washed out after. Wouldn't be so bad but normally it comes back so quickly. It's an awful business.. I guess how long you live with ascites depends on what's causing it... [cancerforums.net]
- Congestive Heart Failure
Read more 11 What are the signs and symptoms congestive heart failure? Shortness of breath: Shortness of breath, initially with exercise, and in more severe cases even at rest. [healthtap.com]
Transudative ascites (Serum Albumin - Ascites Albumin >1.1 gm/dl) Liver cirrhosis Congestive heart failure Hepativ vein obstruction (Budd Chiari syndrome) a. Assoc. with tumors (hepatoma, hypernephroma, pancreatic Ca) b. [enotes.tripod.com]
Some other causes of ascites related to increased pressure gradient are congestive heart failure and advanced kidney failure due to generalized retention of fluid in the body. [medicinenet.com]
May be a complication of cirrhosis, congestive heart failure, malignancy, or peritonitis. Synonym(s): hydroperitoneum, hydroperitonia. [L. fr. [medical-dictionary.thefreedictionary.com]
- Falling
Prairie Spring 2012 Grandpa diagnosed, Stage III PC Summer 2012 Xeloda/Radiation Fall 2012 Scan, Tumour grown and mets to liver, Stage IV 4.5 month break from treatment Winter 2012 Scan, mets appear to be small enough that they can't say for sure what [cancerforums.net]
Lack of preoperative identification of the point of leakage can lead to a 50% surgical failure rate due to inadequate surgical planning while the failure rates fall to 12-18% in patients in whom the rupture site was found at preoperative ERP [ 10 ]. [em-consulte.com]
Cardiovascular
- Hypertension
The entity may mimic spontaneous bacterial peritonitis or ascites due to portal hypertension. Here, the authors discuss a case of pancreatic ascites developing in the setting of alcoholic liver disease with portal hypertension. [ncbi.nlm.nih.gov]
A particular value of recognizing portal hypertension as a cause of ascites is that medical management using diuretics and salt restriction is often effective in portal hypertensive patients. [hepatitiscentral.com]
Gastroenterology 114: 336–343 PubMed CrossRef Google Scholar Jaffe DL, Chung RT, Friedman LS (1996) Management of portal hypertension and its complications. [link.springer.com]
An increase in the pressure within the branches of the portal vein that run through liver (portal hypertension ). Portal hypertension is caused by the scarring that occurs in cirrhosis. [medical-dictionary.thefreedictionary.com]
- Hypotension
BP may be transiently high or low, with significant postural hypotension. Temperature may be normal or even subnormal at first but may increase to 37.7 to 38.3° C (100 to 101° F) within a few hours. Sensorium may be blunted to the point of semicoma. [chirhoclin.com]
BP may be transiently high or low, with significant postural hypotension. Temperature may be normal or even subnormal at first but may increase to 37.7 to 38.3 ° C (100 to 101 ° F) within a few hours. [merckmanuals.com]
Many clinicians are more likely to prescribe albumin after LVP in patients with underlying hypotension or renal dysfunction, as these patients theoretically have the greatest benefit. [clinicaladvisor.com]
Workup
It is suggested that the clinical entity of pancreatic ascites occurs more often than reported and a workup for it should be done even in the face of unconvincing radiographic and angiographic evidence. [ncbi.nlm.nih.gov]
Treatment
Conservative therapy is the most common initial treatment option but has high failure rates hence arguing for interventional therapy as a preferred primary treatment option. [ncbi.nlm.nih.gov]
Prognosis
When the conditions has been diagnosed the prognosis is surprisingly good despite the poor presenting condition of most patients. [ncbi.nlm.nih.gov]
Prognosis The prognosis depends upon the condition that is causing the ascites. Carcinomatous ascites has a very bad prognosis. However, salt restriction and diuretics can control ascites caused by liver disease in many cases. [encyclopedia.com]
Etiology
ERCP demonstrated a pseudocyst and the site of disruption of the pancreatic duct, but not the etiology of the pancreatitis. Following a period of nutritional support, surgery was carried out. [ncbi.nlm.nih.gov]
[…] role of endoscopic retrograde cholangiopancreatography (ERCP) in the setting of acute pancreatitis has primarily been twofold. 1 First, it has been used after resolution of an acute attack, or more commonly multiple attacks, in an attempt to define etiology [abdominalkey.com]
Epidemiology
Many cases remain idiopathic, and at times, the site of ductal disruption is unable to be found.[6][7][8][9] Epidemiology The epidemiology of pancreatic ascites is not well studied and has mostly been reported by smaller retrospective studies and case [ncbi.nlm.nih.gov]
Epidemiology of Ductal Disruption If the underlying pathophysiology of acute pancreatitis is colocalization of zymogen granules with cell membranes, setting off an inflammatory cascade with local effects related to cytokine release and recruitment of [abdominalkey.com]
Stimac D, Mikolasevic I, Krznaric-Zrnic I, et al ; Epidemiology of Acute Pancreatitis in the North Adriatic Region of Croatia during the Last Ten Years. Gastroenterol Res Pract. 20132013:956149. doi: 10.1155/2013/956149. Epub 2013 Feb 14. [patient.info]
Discussion The incidence of chylous ascites in developed countries is approximately one case per 20,000 admissions, although large epidemiological studies are lacking. 1 Among known causes of chylous ascites there are many pathological processes such [scielo.isciii.es]
Pathophysiology
So careful comparative analysis of peritoneal exudate, plasma and lymph with regards to putative mediators of local and remote injury may provide essential pathophysiological clues. [ncbi.nlm.nih.gov]
References: [1] [12] [13] Complications Pancreatic pseudocysts Definition : encapsulated collection of pancreatic fluid ; which develops 4 weeks after an acute attack of pancreatitis ; can occur in both acute and chronic pancreatitis Pathophysiology : [amboss.com]
Pathophysiology of ascites Increased portal venous pressure ( The pathophysiology of ascites due to cirrhosis. ) Any cause of increased resistance to hepatic or portal venous blood flow can lead to ascites. [surgwiki.com]
"Ascites fluid in severe acute pancreatitis: from pathophysiology to therapy". Acta Gastroenterol Belg. 63 (3): 264–8. PMID 11189983. Iacono C, Procacci C, Frigo F, Andreis IA, Cesaro G, Caia S, Bassi C, Pederzoli P, Serio G, Dagradi A (1989). [en.wikipedia.org]
Epidemiology of Ductal Disruption If the underlying pathophysiology of acute pancreatitis is colocalization of zymogen granules with cell membranes, setting off an inflammatory cascade with local effects related to cytokine release and recruitment of [abdominalkey.com]
Prevention
Suggestions for Ascites In order to prevent the development of ascites, it is important to prevent the risk factors that lead to the disease. These precautions can help to prevent Ascites: Avoiding alcohol can prevent liver disease and cirrhosis. [home-remedies-for-you.com]
Prevention Modifying or restricting use of salt can prevent most cases of recurrent ascites. Resources BOOKS Berkow, Robert, editor. The Merck Manual of Medical Information. Whitehouse Station, NJ: Merck Research Laboratories, 1997. [encyclopedia.com]
Can ascites be prevented? The prevention of ascites largely involves preventing the risk factors of the underlying conditions leading to ascites. [medicinenet.com]