Presentation
Present day and probable future developments, such as the use of robotics, natural orifice techniques, and major vascular reconstruction are also presented. [ncbi.nlm.nih.gov]
Gastrointestinal
- Abdominal Pain
Chronic pancreatitis can also manifest with abdominal pain, and diabetes. Diagnosis of pancreatic insufficiency Pancreatic insufficiency is suspected in a patient who develops diabetes, upper abdominal pain and features of malabsorption. [ddc.musc.edu]
METHODS: Patients with unknown cause of upper abdominal pain suggesting pancreatic disease without a history of alcohol consumption were prescribed a low-fat diet ( RESULTS: Of 45 patients, 14 were in the suggestive group, 18 were in the indeterminate [ncbi.nlm.nih.gov]
Pain can occur when a tumor, typically originating in the body or the tail of the pancreas, grows to put pressure on surrounding abdominal organs or invades surrounding nerves. Many other conditions can cause upper abdominal pain. [sharecare.com]
- Abdominal Mass
Diagnosis of cystadenocarcinoma is made by abdominal CT or MRI, which typically shows a cystic mass containing debris; the mass may be misinterpreted as necrotic adenocarcinoma or pancreatic pseudocyst. [merckmanuals.com]
[…] problems ( ascites, abdominal mass) Depression Venous thrombosis Palpable lymph nodes (cervical, clavicular) The symptoms of pancreatic cancer are generally vague and can easily be attributed to other less serious and more common conditions. [emedicinehealth.com]
[…] disease: Presence of ascites, a palpable abdominal mass, hepatomegaly from liver metastases, or splenomegaly from portal vein obstruction Advanced disease: Paraumbilical subcutaneous metastases (or Sister Mary Joseph nodule or nodules) Possible presence [emedicine.medscape.com]
[…] palliative care [1] Prognosis Five year survival rate 5% [6] [7] Frequency 393,800 (2015) [8] Deaths 411,600 (2015) [9] Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass [en.wikipedia.org]
- Dyspepsia
OBJECTIVES: The objective of this study was to examine the efficacy of low-fat diet against dyspepsia in patients who had endosonographic evidence of nonalcoholic mild pancreatic disease. [ncbi.nlm.nih.gov]
- Epigastric Pain
METHODS: Patients with upper abdominal pain suggesting pancreatic disease (persistent over hours, pain aggravated by ingestion of food, epigastric pain radiating to the back), without a history of alcohol consumption and who exhibited no abnormalities [ncbi.nlm.nih.gov]
Insulinoma causes repeated episodes of hypoglycemia, sweating, and tremors, while patients with gastrinoma have inflammation of the esophagus, epigastric pain, multiple ulcers, and possibly diarrhea. [encyclopedia.com]
Liver, Gall & Pancreas
- Pancreatic Pain
Most occur in people over age 60. chronic pancreatitis or pancreatic cysts: Someone with chronic pancreatitis (painful inflammation of the pancreas) may have increased risk for pancreatic cancer. diabetes: Pancreatic cancer is more common in people who [medbroadcast.com]
Severe acute pancreatitis is a medical emergency. What Are the Symptoms of Chronic Pancreatitis? Pain is less common in chronic pancreatitis than in acute pancreatitis. Some people have pain, but many people do not experience abdominal pain. [emedicinehealth.com]
Musculoskeletal
- Mid Back Pain
Mid-back pain or discomfort Where a bra strap would sit and may be eased by leaning forward. Indigestion Not responding to medication. Pale and smelly stools That don’t flush easily. [pancreaticcanceraction.org]
Workup
CT scan is a very common study used in the USA for the workup of liver tumors. The ideal study is multi-phase CT scan with the use of oral and IV contrast. MRI can provide sectional views of the body in different planes. [patients.gi.org]
The relative 1-year survival rate for pancreatic cancer is only 28%, and the overall 5-year survival is 7%. [11] (See Prognosis and Workup .) Types of pancreatic cancer Of all pancreatic cancers, 80% are adenocarcinomas of the ductal epithelium. [emedicine.medscape.com]
X-Ray
- Pancreatic Calcification
Also, tropical pancreatitis, seen predominantly in South India and Africa, can lead to early onset diabetes and pancreatic calcifications and is associated with a probable increased risk. C. [clinicaladvisor.com]
Treatment
Abstract Pyloric exclusion with gastrojejunostomy has been shown to be an effective adjuvant in the treatment of severe duodenal and pancreatic trauma. [ncbi.nlm.nih.gov]
Unfortunately, by this point, treatment options are limited. [my.clevelandclinic.org]
“Knowing which sub-type a patient has would allow a doctor to provide a more accurate prognosis and treatment recommendations.” [theguardian.com]
Prognosis
In those patients undergoing surgical resection for pancreatic duct-cell carcinomas, the prognosis of patients who were negative for the anti-p53 antibodies was better than patients who were positive. [ncbi.nlm.nih.gov]
Prognosis for pancreatic cancer Prognosis means the expected outcome of a disease. You will need to discuss your prognosis and treatment options with your doctor, but it is impossible for any doctor to predict the exact course of your disease. [cancer.org.au]
Prognosis Because adenocarcinoma of the pancreas has often spread to other parts of the body before it is discovered, the prognosis for pancreatic cancer is very poor. [merckmanuals.com]
"Knowing which sub-type a patient has would allow a doctor to provide a more accurate prognosis and treatment recommendations. [independent.co.uk]
Etiology
EUS cyst morphology, as well as fluid analysis obtained by fine needle aspiration, can often be used to diagnose the etiology of these lesions, helping the clinician to more accurately assess the presence or potential for malignancy. [ncbi.nlm.nih.gov]
Certain blood tests will also be obtained to look for the etiology of the pancreatitis, such as triglyceride and calcium levels. A history of alcoholism and/or smoking points to these as a cause. [pancreapedia.org]
Advances in the Etiology of Chronic Pancreatitis. Dig Dis 28 p324-329, 2010. Available online at http://www.ncbi.nlm.nih.gov/pubmed/20814206 through http://www.ncbi.nlm.nih.gov. Accessed April 2011. [labtestsonline.org]
Epidemiology
Abstract Findings from epidemiologic studies and research with experimental animal models provide insights into alcohol-related disease pathogeneses. [ncbi.nlm.nih.gov]
Vitamin D found to slash risk of pancreatic cancer 9/12/2006 - New research published in the journal Cancer Epidemiology Biomarkers and Prevention indicates that vitamin D could significantly reduce the risk of pancreatic cancer. [naturalnews.com]
Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review. Pancreas 33: 323–330, 2006. PMID: 17079934 Banks PA. Epidemiology, natural history, and predictors of disease in acute and chronic pancreatitis. [pancreapedia.org]
Pathophysiology
Pancreatic physiology, pathophysiology, acute and chronic pancreatitis. Gastrointestinal Teaching Project, American Gastroenterologic Association. 2003. Figure 3. The ductal anatomy. [pancreapedia.org]
Diabetes mellitus [ edit ] The pancreas is central in the pathophysiology of both major types of diabetes mellitus. [en.wikipedia.org]
11:35 am Discussion 11:35 am - 11:50 am Selected from Poster Abstracts: Anguraj Sadanandam (Institute of Cancer Research (ICR), United Kingdom) "Multi-Omics and Cross-Species Subtypes in Pancreatic Neuroendocrine Tumors with Distinct Cellular Origin, Pathophysiology [grc.org]
Pathophysiology Typically, pancreatic cancer first metastasizes to regional lymph nodes, then to the liver and, less commonly, to the lungs. [emedicine.medscape.com]
Prevention
Second, screening for NAFPD may identify individuals at risk for developing type 2 diabetes mellitus for targeted prevention. [ncbi.nlm.nih.gov]
Their findings reveal magnesium can help prevent pancreatic cancer. Indulging in dark chocolate could, therefore, be more than just a treat - it could actually benefit a person's health. [dailymail.co.uk]