Edit concept Question Editor Create issue ticket

Pancreatic Duct Obstruction


Presentation

  • Abstract We present the case of a 65-year-old man with a pancreatic nonfunctioning neuroendocrine tumor causing main pancreatic duct obstruction that presented as excessive hyperglycemia.[ncbi.nlm.nih.gov]
  • Similar to our case, 17 of 20 patients presenting with AOSPD had a history significant for chronic pancreatitis. Of the 20 patients, 10 had a prior pancreatic procedure within 1 month of presentation.[acgcasereports.gi.org]
  • If liver disease is present, both procedures can be used to uncover and treat damage resulting from poor liver function, such as bleeding due to portal vein hypertension.[cpmc.org]
  • We present the case of a 66-year old woman who presented to our emergency department with severe upper abdominal pain and vomiting.[saudisurgj.org]
Abdominal Pain
  • Upper Abdominal Pain In Pancreatic Cancer : Abdominal pain is a common symptom. It often radiates to the middle or upper back and worsens after eating or when lying down. Upper abdominal pain commonly occurs with advanced pancreatic cancer.[columbiasurgery.org]
  • Symptoms of chronic pancreatitis include abdominal pain, nausea, vomiting, weight loss, diarrhea, and diabetes. Abdominal pain is the most common presenting symptom. The abdominal pain is typically epigastric and radiates to the back.[pancreapedia.org]
  • It may also be used to rule out other conditions that can cause abdominal pain.[nyulangone.org]
  • Pancreatitis Pancreatic duct blockages can lead to pancreatitis, an inflammatory process that can cause severe abdominal pain, vomiting, and diarrhea.[hopkinscf.org]
  • Case Report A 66 year old female patient presented to the emergency department with severe abdominal pain and vomiting.[saudisurgj.org]
Overeating
  • However, the frequency of SAP remains stable over time. Biliary calculi and alcohol abuse are the most common causes of AP. Other causes such as iatrogenic factors, sphincter of Oddi dysfunction (SOD) and eating disorders also cannot be omitted.[ncbi.nlm.nih.gov]
  • And one day, I was pulling some garden hose over our wood deck, and I noticed the sound was eerily like the radiation machine as it would move into position.”[pancreatica.org]
  • Severe pancreatitis, especially if it is not diagnosed and treated quickly, can lead to inflammation all over the body, called systemic inflammatory response syndrome.[nyulangone.org]
  • As the pancreas begins to scar and more than 90% of the tissue is destroyed over time (often over many years) patients develop fatty stools and fat malabsorption because they do not produce enough digestive enzymes; and diabetes due to loss of insulin[pancreapedia.org]
  • Bile backing up into the pancreatic duct may initiate pancreatitis. [9] The pancreatic duct is generally regarded as abnormally enlarged if being over 3 mm in the head and 2 mm in the body or tail. [10] Pancreatic ductal carcinoma is a common form of[en.wikipedia.org]
Colic
  • (bilious) (infantile) (intestinal) (recurrent) (spasmodic) R10.83 ICD-10-CM Diagnosis Code R10.83 Colic 2016 2017 2018 2019 Billable/Specific Code Pediatric Dx (0-17 years) Applicable To Colic NOS Infantile colic Type 1 Excludes colic in adult and child[icd10data.com]
  • […] atrophic pancreas (duct) (senile) 577.8 Burke's syndrome 577.8 Calcification pancreas 577.8 Calculus, calculi, calculous 592.9 pancreas (duct) 577.8 Cirrhosis, cirrhotic 571.5 pancreas (duct) 577.8 Clarke-Hadfield syndrome (pancreatic infantilism) 577.8 Colic[icd9data.com]
  • The differential diagnosis of acute pancreatitis includes a perforated gastric or duodenal ulcer, mesenteric infarction, strangulating intestinal obstruction, ectopic pregnancy, dissecting aneurysm, biliary colic, appendicitis, diverticulitis, inferior[chirhoclin.com]
Clay-Colored Stool
  • Dark urine and light or clay-colored stools can also be associated with jaundice. Jaundice occurs when bilirubin, a component of bile, builds up in your blood.[columbiasurgery.org]
Epigastric Pain
  • Although there is occasionally no pain, severe epigastric pain may last many hours or several days.[chirhoclin.com]
Pancreatic Pain
  • pain Pancreatic trypsinogen deficiency Pancreatitis (inflammation of pancreas) from gallstone Pancreatitis, gallstone Pseudolipomatosis hypertrophy of pancreas Pseudopancreatic cholera syndrome Subcutaneous nodular fat necrosis in pancreatitis 577.8[icd9data.com]
  • Medical treatment of chronic pancreatic pain is often unsatisfactory.[chirhoclin.com]
  • Introduction In patients with chronic pancreatitis, pain is the predominant symptom and remains a therapeutic challenge.[nejm.org]
Neglect
  • However, it is often neglected in follow up. This study was to review the outcomes of pancreatic duct obstruction and explore the prevention of pancreatic duct obstruction.[ncbi.nlm.nih.gov]

Treatment

  • Endoscopic dilatation is one of the treatment options for stenosis of pancreaticogastrostomy (PG). However, the failure of endoscopic dilatation necessitates surgical approaches.[ncbi.nlm.nih.gov]
  • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer. National Cancer Institute of the United States. National Cancer Institute of Canada. ‎[books.google.de]
  • Two months previously, he had suffered an attack of acute pancreatitis that was resolved with conservative treatment.[ncbi.nlm.nih.gov]
  • Endoscopic sphincterotomy (EST) and nasobiliary drainage, which target the cause of AP, may prevent the transformation from AP to SAP and this may be adopted as an essential treatment strategy.[ncbi.nlm.nih.gov]
  • Armed with the extra confidence, Dale decided to proceed with the recommended treatment, consisting of a bookended three days of 5-FU, surrounding 25 days of radiation. Treatment is a surreal time in some ways.[pancreatica.org]

Prognosis

  • To keep learning about pancreatic cancer: Overview Causes Symptoms Genetics Diagnosis Treatment Prognosis Coping[columbiasurgery.org]
  • But not the difficult prognosis. But she feels sure that Dale knew, even if he doesn’t now recall. He went straight to the Internet, began reading voraciously, and grew visibly depressed. She finally had to tell him to just stop reading.[pancreatica.org]
  • Outlook (Prognosis) If the blockage is not corrected, it can lead to life-threatening infection and a dangerous buildup of bilirubin. If the blockage lasts a long time, chronic liver disease can result.[stlukes-stl.com]
  • Acute pancreatitis: value of CT in establishing prognosis. Radiology 1990; 174: 331-336. Mortele KJ, Wiesner W, Intriere L, Shankar S, Zou KH, Kalantari BN, Perez A, vanSonnenberg E, Ros PR, Banks PA, Silverman SG.[sapd.es]

Etiology

  • Advances in the Etiology of Chronic Pancreatitis. Dig Dis 28 p324-329, 2010. Available online at through . Accessed April 2011.[labtestsonline.org]
  • Article 143 Downloads 1 Citations Opinion statement The treatment of pancreatic duct strictures is based on an accurate assessment of the etiology of the disease, and then the degree of symptomatology.[link.springer.com]
  • Her medical history was significant for type 2 diabetes and chronic pancreatitis of unclear etiology, possibly hereditary given a history of pancreatic cancer on her maternal side.[acgcasereports.gi.org]
  • Etiology and Pathogenesis Biliary tract disease and alcoholism account for 80% of hospital admissions for acute pancreatitis.[chirhoclin.com]
  • The age at presentation varies with etiology.[pancreapedia.org]

Epidemiology

  • Epidemiology of alcohol-related liver and pancreatic disease in the United States. Arch Intern Med 168:649–656, 2008. PMID: 18362258[pancreapedia.org]
  • The epidemiology and impact of pancreatic diseases in the United States. Curr Gastroenterol Rep 2005;7:90-5. [ PUBMED ] 9. Ochiai K, Kaneko K, Kitagawa M, Ando H, Hayakawa T.[saudisurgj.org]
  • .), and Clinical Epidemiology, Biostatistics, and Bioinformatics (M.G.W.D.), Academic Medical Center, Amsterdam. Address reprint requests to Dr.[nejm.org]
Sex distribution
Age distribution

Pathophysiology

  • Pancreatic physiology, pathophysiology, acute and chronic pancreatitis. Gastrointestinal Teaching Project, American Gastroenterological Association. 2003.[pancreapedia.org]

Prevention

  • This study was to review the outcomes of pancreatic duct obstruction and explore the prevention of pancreatic duct obstruction.[ncbi.nlm.nih.gov]
  • Endoscopic sphincterotomy (EST) and nasobiliary drainage, which target the cause of AP, may prevent the transformation from AP to SAP and this may be adopted as an essential treatment strategy.[ncbi.nlm.nih.gov]
  • Preventing a recurrence is a major goal of treatment, with efforts focused on identifying the underlying cause and triggers to prevent future episodes.[pancreasfoundation.org]
  • Prevention Be aware of any risk factors you have, so that you can get prompt diagnosis and treatment if a bile duct becomes blocked. The blockage itself may not be preventable. References Anstee QM, Jones DEJ. Liver and biliary tract disease.[stlukes-stl.com]
  • Causes a blockage of the pancreatic duct and can prevent pancreatic enzymes from reaching the duodenum where they normally do their work.[quizlet.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!