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Pancreatic Neoplasm


Presentation

Abdominal Mass
  • We report a case of a 32-year-old pregnant woman with a 7-month history of pain and a left upper quadrant abdominal mass. She arrived at the emergency department with exacerbation of her symptoms during week 15 of gestation.[ncbi.nlm.nih.gov]
  • Javle et al. [23] found that palpable abdominal mass on presentation was significantly more in the malignant group (4/17 patients) than in the benign group (0/18 patients).[dx.doi.org]
  • A 61 year old patient admitted to the Internal Medicine Ward 3 at Coimbra University Hospital presents with a volumous intra-abdominal mass in the left hypochondrium and microcytic anemia.[rihuc.huc.min-saude.pt]
  • mass Also symptoms related to an intra-abdominal mass effect, such as discomfort, nausea, vomiting and early satiety Radiology description Well circumscribed, encapsulated, heterogeneous pancreatic lesion with cystic degeneration on CT or MRI Radiology[pathologyoutlines.com]
Hepatomegaly
  • Physical examination may reveal jaundice, temporal wasting, peripheral lymphadenopathy, hepatomegaly, and ascites.[ncbi.nlm.nih.gov]
  • Patients presenting with or developing advanced intra-abdominal disease may have ascites, a palpable abdominal mass, hepatomegaly from liver metastases, or splenomegaly from portal vein obstruction.[emedicine.medscape.com]
  • Depression Migratory thrombophlebitis (ie, Trousseau sign) and venous thrombosis: May be the first presentation Palpable gallbladder (ie, Courvoisier sign) Developing, advanced intra-abdominal disease: Presence of ascites, a palpable abdominal mass, hepatomegaly[emedicine.com]

Workup

  • Here, we report a 69-year-old male patient with distal pancreatic mass incidentally found during a CT scan workup for a pulmonary nodule suspicious for metastatic prostate adenocarcinoma.[ncbi.nlm.nih.gov]
  • Discusses current guidelines in the workup and management of tumors of the exocrine pancreas. Google Scholar 6. Demos TC, et al. Cystic lesions of the pancreas. Am J Roentgenol. 2002;179(6):1375–88. CrossRef Google Scholar 7. Coursey CA, et al.[link.springer.com]

Treatment

  • The patient made an excellent recovery on anti-tuberculous treatment, and no evidence of a tumor was seen on a CT scan performed 6 months after the initiation of treatment.[ncbi.nlm.nih.gov]
  • New studies examining neoadjuvant and adjuvant treatment of pancreatic cancer show some promise. The surgical treatment and palliation of pancreatic cancer continues to advance.[journals.lww.com]

Prognosis

  • […] of General Surgery, La Princesa University Hospital, Madrid, Spain. i.rubio@aecirujanos.es Abstract CONTEXT: Colloid carcinoma is considered a distinct type of pancreatic neoplasia with specific histopathological and molecular features, and a better prognosis[ncbi.nlm.nih.gov]
  • Most of these lesions are benign or slow growing and the prognosis is significantly better than with pancreatic adenocarcinoma.[bcm.edu]
  • 857 genes associated with favourable prognosis.[proteinatlas.org]

Etiology

  • However, it s etiology still maintain discussions. AIM: To analyze it s clinical data, diagnosis and treatment. METHODS: A retrospective study of medical records of all patients treated from January 1997 until July 2015.[ncbi.nlm.nih.gov]
  • Etiology and risk factors The specific risk factors for pancreatic cancer are not as striking as those for other gastrointestinal (GI) malignancies, such as esophageal and gastric carcinomas.[web.archive.org]
  • The differences in rates of pancreatic cancer among countries, the changes in rates over time, and the increases among migrants moving from low-risk to high-risk areas suggest that other factors may also play an etiologic role.[doi.org]

Epidemiology

  • […] of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. [2] Cancer Genomics Research Laboratory, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Leidos Biomedical[ncbi.nlm.nih.gov]
  • Inoue M, Tajima K, Takezaki T et al (2003) Epidemiology of pancreatic cancer in Japan: a nested case-control study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC).[dx.doi.org]
  • Michaud, Epidemiology of pancreatic cancer, Minerva Chir. 59 (2004) 99-111. [16] M. Edderkaoui, E. Thrower, Smoking induced pancreatitis and pancreatic cancer, Pancreapedia: Exocrine Pancreas Knowledge Base, (2015). DOI: [18] L. Wang, G. Yang, X.[scipress.com]
Sex distribution
Age distribution

Pathophysiology

  • ., USA; b Service d'Hépato-Gastroentérologie, CHU de Reims, Hôpital Robert Debré, Reims, France; c University of Florence, Florence, Italy; d Department of Endocrinology, Erasmus MC University, Rotterdam, The Netherlands; e Department of Pathophysiology[doi.org]
  • There have been advances in PNET diagnosis, tumor localization, and therapies in the last decade, and increased understanding of their pathophysiology is likely to be rewarded with new and emerging treatments for PNETs in the not too distant future.[ncbi.nlm.nih.gov]

Prevention

  • The aim of this study was to review the prevention and treatment of pancreatic fistula as performed by our department.[ncbi.nlm.nih.gov]
  • Causes, Risk Factors, and Prevention Learn about the risk factors for pancreatic cancer and what you might be able to do to help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of pancreatic cancer.[cancer.org]
  • For more, see the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention.[web.archive.org]

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