The patient is a 24-yr-old African American woman, who presented with a pancreatic mass, hepatic masses, and abdominal lymphadenopathy. [ncbi.nlm.nih.gov]

A 3-year-old boy with nausea and general fatigue was referred to our center. Imaging studies showed an approximately 7.5-cm, left-sided abdominal mass and multiple metastases in the lung. [ncbi.nlm.nih.gov]

Symptoms - Pancreatoblastoma * Asymptomatic in early stages * Upper abdominal pain * Abdominal pain above the bellybutton * Gastrointestinal obstruction * Vomiting * Jaundice * Weight loss * Enlarged abdomen * Abdominal mass * Loss of appetite * Fatigue [checkorphan.org]

They include growth problems (in children), obesity (in adults), hair loss, slow heart rate, low blood sugar, low blood pressure, fatigue, and problems with reproduction. [cancer.gov]

The following signs and symptoms may be noted: Failure to thrive (infants) Distended abdomen Abdominal pain, back pain Loss of appetite Weight loss Indigestion Yellowing of skin (jaundice) Nausea and vomiting Dark-colored urine Fatigue (getting tired [dovemed.com]

[PMID 16185976] Savides TJ, Donohue M, Hunt G, Al-Haddad M, Aslanian H, Ben-Menachem T, et al. EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. [pancreas.imedpub.com]

One was a 3.5-year-old boy who presented with abdominal pain. Physical examination demonstrated abdominal masses. Multiple pancreatic and hepatic masses were noted by magnetic resonance imaging. [ncbi.nlm.nih.gov]

Case report: A 7 year old boy presented with recurrent vomiting, weight loss and an abdominal lump. Work up revealed a large tumor arising from the pancreas encasing major vessels and the biopsy was suggestive of a pancreatoblastoma. [hpbonline.org]

The aspiration smears of the liver mass showed a biphasic tumor composed of bland-appearing primitive spindled stromal fragments with "spider-web"-like long fibrils interconnecting with sharply angulated islands of cohesive epithelium. [ncbi.nlm.nih.gov]

An initial fine needle aspiration of the pancreatic mass was nondiagnostic, and a subsequent fine needle aspiration of a liver mass was read as metastatic acinar cell carcinoma. [springerlink.com]

Therefore, a needle biopsy of the liver mass was obtained and was initially diagnosed as a neuroendocrine carcinoma, consistent with metastasis from a pancreatic primary. [archivesofpathology.org]

CASE REPORT A 27-year-old woman with a past medical history of iron deficiency anemia from dysfunctional uterine bleeding presented with a 2-month history of pressure like chest pain, shortness of breath, and right shoulder pain. [pancreas.imedpub.com]

Large epithelioid cells islands or whorled nests of spindled cells, as well as keratosis, may be visible. In contrast to the surrounding cells, cells in the squamoid corpuscle has large oval nuclei, with inconspicuous nucleoli. [ijpmonline.org]

Occasionally, adult pancreatoblastoma causes liver function test abnormalities due to biliary obstruction or hepatic metastasis. Imaging Most tumors are well-defined on crosssectional imaging. [pancreas.imedpub.com]

Liver function test abnormalities [ 11 ] and anemia are sometimes reported [ 12 ]. [ncbi.nlm.nih.gov]

The initial liver biopsy diagnosis was metastatic neuroendocrine carcinoma based on morphology and synaptophysin positivity. At pancreatic resection, the diagnostic features of pancreatoblastoma were recognized. [ncbi.nlm.nih.gov]

The neuroendocrine-appearing component was positive for synaptophysin, which was also seen in the original liver biopsy and which helped lead to the initial diagnosis of neuroendocrine carcinoma. [archivesofpathology.org]

(d) Histological image showing the surgical resection of the pancreatic tumour, the characteristics of which were similar to those observed in the previous liver biopsy (H & E, 200 ). [ecancer.org]