Presentation
Upon six months follow-up, the girl has no pain and presents no functional repercussion in daily life. [scienceopen.com]
At the onset she presented mechanical pain of the left hip and later a stress fracture of the femur for which she was treated with surgery, pamidronate and zolendronate. Pathology confirmed the diagnosis. Phosphocalcic metabolism was normal. [reumatologiaclinica.org]
Treatment
Denosumab treatment for fibrous dysplasia. J Bone Miner Res 2012; 27(7):1462-70. doi: 10.1002/j bmr.1603 7) Lovy A, Dowdell J, Keswani A, Koehler S, Kim J, Weinfeld S, et al. [revista.rmu.org.uy]
Treatment is dictated by the tissues affected, and the extent to which they are affected. Generally, some form of surgical intervention is recommended. Bisphosphonates are frequently used in the treatment of FD. [scienceopen.com]
Evaluation and treatment. Pediatr Clin North Am, 43 (1996), pp. 949-966 [6] D.M. Riddell. Malignant change in fibrous displasia. J Bone Joint Surg Br, 46 (1964), pp. 251-255 [7] J.M. Lane, S.N. Khan, W.J. O’Connor, M. Nydick, J.P. Hommen, R. [reumatologiaclinica.org]
Prognosis
The prognosis depends on the extension and degree of bone affection, age at onset and extraskeletal manifestations.2 The malignity rate is rare.6 In case of pain, deformity or fracture, treatment with biphosphonate is recommended.7 Curetage or bone implants [reumatologiaclinica.org]
The study presents the characteristics of this condition, as well as its vital and functional prognosis. Record: found Abstract: found Article: not found Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. [scienceopen.com]
Pathophysiology
The role of type 1 and type 2 5’-deiodinase in the pathophysiology of the 3,5,3’-triiodothyronine toxicosis of McCune-Albright syndrome. [revista.rmu.org.uy]
We briefly review the clinical and pathophysiologic features of the disorder and offer this guide in response to the conference recommendation, based on our collective accumulated experience in the management of this complex disorder. [scienceopen.com]