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2.1
Parainfluenza Virus

Presentation

Furthermore, we review the current research surrounding BACM, overview the clinical presentation to healthcare professionals, and present an interesting case of a child presenting for the second time with BACM. [ncbi.nlm.nih.gov]

[…] patients presented with the symptom (p 2 ). [bmcinfectdis.biomedcentral.com]

Entire Body System

  • Turkish

    INFECTIOUS DISEASE BACTERIOLOGY IMMUNOLOGY MYCOLOGY PARASITOLOGY VIROLOGY En Español VIROLOGY - CHAPTER SIXTEEN PARAINFLUENZA, RESPIRATORY SYNCYTIAL AND ADENO VIRUSES Dr Margaret Hunt Professor Emerita University of South Carolina School of Medicine TURKISH [microbiologybook.org]

Respiratoric

  • Dyspnea

    All patients presented with cough, 14 had dyspnea, 11 had hypoxia, and 8 had a fever. Patients received 5 to 10 days of treatment. Nine patients (56%) had a complete clinical response after DAS181 therapy and 4 (25%) had a partial response. [ncbi.nlm.nih.gov]

    Now onto this week’s podcast Podcast: Play in new window | Download (Duration: 17:31 — 40.1MB) Subscribe: Apple Podcasts | Android | Email | Google Podcasts | RSS Question 1 A 4-week-old boy presents with a 2-week history of increasing dyspnea, cough, [roshreview.com]

    HPIV-3 patients significantly presented less dyspnea, cough, chest retractions, crackles and radiologic abnormalities than RSV patients. [scielo.br]

    Pneumonia developed in 3 of the 12 patients, with pulmonary infiltrates on chest x-ray, dyspnea and hypoxia. One of the 3 patients with pneumonia had metastatic renal cell carcinoma and severe (grade 4) acute GVHD. [academic.oup.com]

    In this study, patients with lower respiratory tract involvement were defined as having signs or symptoms of pulmonary infection or compromise (i.e., rales, wheezes, dyspnea, an infiltrate on chest radiography, or an alveolar-to-arterial oxygen gradient [nejm.org]

  • Paroxysmal Cough

    Infection was associated with symptoms of bronchiolitis or pneumonia in 5 children, paroxysmal coughing in 3 infants, apnea in 1 newborn, and aseptic meningitis in 1 child. Hospitalization was required for 8 of the 10 children. [ncbi.nlm.nih.gov]

    3, 4, 7, 21 14, 1, 2, 5, 35 Pneumonia Fever, respiratory distress, cough, severe in young children and infants 7 1, 2, 3,4, 14, 21, 7b Pertussis-like Syndrome Fever, paroxysmal cough, post-tussive vomiting 5 1, 2, 3, 12, 14, 19, 21, 35 Acute Respiratory [microbiologybook.org]

Gastrointestinal

  • Abdominal Pain

    […] glands in the neck or jaw area Fever, chills Bad breath In children, symptoms may also include: Nausea Vomiting Abdominal pain Treatments for Tonsillitis Treatment for tonsillitis will depend in part on the cause. [webmd.com]

Cardiovascular

  • Heart Failure

    These conditions include: cardiac disease, including cyanotic congenital heart disease, coronary artery disease and congestive heart failure chronic respiratory conditions, including suppurative lung disease, chronic obstructive pulmonary disease and [health.nsw.gov.au]

Neurologic

  • Irritability

    Other symptoms of HPIV illness may include— sore throat, sneezing, wheezing, ear pain, irritability, and decreased appetite. If your symptoms are severe or do not improve, you should seek medical attention. [cdc.gov]

    While symptoms may vary child-to-child, the most common include: runny nose redness or swelling of the eyes barky cough noisy, harsh breathing hoarse voice or cry rattling felt over the chest or back wheezing fever irritability decreased appetite vomiting [childrenshospital.org]

    Symptoms may include: Runny nose Redness or swelling of the eyes Barky (seal-like) cough Noisy, harsh breathing Hoarse voice when speaking or crying Rattling felt over the chest or back when breathing Wheezing Fever Irritability Decreased appetite Vomiting [chop.edu]

Workup

Microbiology

  • Streptococcus Pneumoniae

    […] influenzae, Moraxella catarrhalis Amoxicillin Acute sinusitis S. pneumoniae, H. influenzae, M. catarrhalis Amoxicillin if symptoms persist for >10 days Pharyngitis Streptococcus pyogenes (group A Streptococcus ), viruses (e.g., adenovirus) Penicillin [accessmedicine.mhmedical.com]

    J12.89 Other viral pneumonia J12.9 Viral pneumonia, unspecified J13 Pneumonia due to Streptococcus pneumoniae J14 Pneumonia due to Hemophilus influenzae J15 Bacterial pneumonia, not elsewhere classified J15.0 Pneumonia due to Klebsiella pneumoniae J15.1 [icd10data.com]

    Apart from the isolation of a strain of Streptococcus pneumoniae from the sputum of the index case (case 1), which is likely due to a secondary bacterial infection, all sputum cultures from other cases were negative for respiratory pathogens. [jcm.asm.org]

Treatment

Treatment of A549 cells with α2,3 linkage-specific sialyltransferase increased infectivities of both hPIV1 and hPIV3, whereas α2,6 linkage-specific sialyltransferase treatment increased only hPIV3 infectivity. [ncbi.nlm.nih.gov]

Treatment: Most infections in adults and older children are mild and recovery takes place without treatment, unless the person is very old or has an abnormal immune system. [en.vircell.com]

Prevention and Treatment Currently, there is no vaccine to prevent HPIV infection. However, researchers are trying to develop vaccines. Also, there is no specific antiviral treatment for HPIV illness. [cdc.gov]

Prognosis

The prognosis was originally reported as grave; however, a mild form of the disease has recently been described. [ncbi.nlm.nih.gov]

Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis; Nam SY, Lee HS, Jung GA, Choi J, Cho SJ, Kim MK, Kim WH, Lee BL; APMIS. 2003 Dec;111(12):1105-13. [ncf-net.org]

Etiology

While not all hemorrhagic pneumonias are caused by very contagious agents, the etiology must be correctly determined in order to administer appropriate patient care. [ncbi.nlm.nih.gov]

Viral etiology and epidemiology of acute respiratory infections in children in Nairobi, Kenya. Am J Trop Med Hyg 1988 ;39:632-40. [ Links ] 20. Lina B., Valette M., Foray S., et al. [scielo.br]

Bacterial etiologies of some of the common upper respiratory tract infections may be primary or superinfections of the original viral processes and are amenable to treatment ( Table 75–1 ). [accessmedicine.mhmedical.com]

Epidemiology

Epidemiological Features HPIVs are spread from respiratory secretions through close contact with infected persons or contact with contaminated surfaces or objects. [gov.uk]

The epidemiologic relatedness of hPIV-3 strains was investigated by sequencing of the haemagglutinin-neuraminidase and fusion protein genes. [ncbi.nlm.nih.gov]

Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 55 (‎23)‎, 175. https://apps.who.int/iris/handle/10665/223088 Revista Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 55 (‎23)‎: 175 [apps.who.int]

Clinical and epidemiological characteristics of the study population and of children infected by HPIV are showed in the Table 1. [scielo.br]

Prevention

This work demonstrates the promise of mNGS for providing rapid information for infection prevention in addition to microbial detection. [ncbi.nlm.nih.gov]

In outbreak and cluster settings, to prevent onward transmission, strict attention to infection control measures such as hand washing and wearing protective equipments should decrease or prevent spread of infection. [gov.uk]

Prevention and Treatment Currently, there is no vaccine to prevent HPIV infection. However, researchers are trying to develop vaccines. Also, there is no specific antiviral treatment for HPIV illness. [cdc.gov]

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