Furthermore, we review the current research surrounding BACM, overview the clinical presentation to healthcare professionals, and present an interesting case of a child presenting for the second time with BACM. [ncbi.nlm.nih.gov]

• Sudden Infant Death Syndrome

  We report a child with Sudden Infant Death Syndrome (SIDS), aged 16 months. The histological findings of tonsils, spleen, and bone marrow revealed many hemophagocytic cells. [ncbi.nlm.nih.gov]

• Poor Growth

  Live attenuated RSV strains in particular are difficult to develop due to their poor growth and physical instability, but these obstacles could be avoided by the use of a vaccine vector. [ncbi.nlm.nih.gov]

• Periodic Breathing

  Apnea and periodic breathing were observed in 1 patient, opsoclonus-myoclonus in another, and disease mimicking herpes encephalitis in the third. All 3 patients recovered without neurologic residua. [ncbi.nlm.nih.gov]

• Mild Clinical Course

  A case of parainfluenza virus-associated acute necrotizing encephalopathy in a Caucasian child with a mild clinical course and excellent prognosis is presented. [ncbi.nlm.nih.gov]

• Hepatosplenomegaly

  A 33-year-old Chilean man with fever secondary to parainfluenza 2 virus infection developed progressive cholestasis, hepatosplenomegaly, cytopenia and an increased ferritin level ( 2000 IU/L). A bone marrow analysis showed hemophagocytosis. [ncbi.nlm.nih.gov]

• Calf Pain

  Presentation is typically with acute onset calf pain and tenderness and refusal to walk or altered gait during the convalescent period of an influenza A or B infection. [ncbi.nlm.nih.gov]

• Myoclonus

  Apnea and periodic breathing were observed in 1 patient, opsoclonus-myoclonus in another, and disease mimicking herpes encephalitis in the third. All 3 patients recovered without neurologic residua. [ncbi.nlm.nih.gov]

• Viral Inclusion Body

  Viral inclusion bodies (IBs), or replication factories, are unique structures generated by viral proteins together with some cellular proteins as a platform for efficient viral replication, but little is known about the mechanism underlying IB formation [ncbi.nlm.nih.gov]

• Cytoplasmic Inclusion Bodies

  Although ATL cells were not detected in the autopsied lungs and a variety of other tissues, cytoplasmic inclusion bodies, which are commonly observed in RNA viral infection, were abundantly observed in the autopsied lung tissue. [ncbi.nlm.nih.gov]

Of the 7 patients with virologic and spirometric data, 5 had 1-log reduction in nasopharyngeal swab PIV viral load and 4 had improved forced expiratory volumes by the end of treatment. [ncbi.nlm.nih.gov]

Treatment : Most infections in adults and older children are mild and recovery takes place without treatment, unless the person is very old or has an abnormal immune system. [en.vircell.com]

The prognosis was originally reported as grave; however, a mild form of the disease has recently been described. [ncbi.nlm.nih.gov]

Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis; Nam SY, Lee HS, Jung GA, Choi J, Cho SJ, Kim MK, Kim WH, Lee BL; APMIS. 2003 Dec;111(12):1105-13. [ncf-net.org]

While not all hemorrhagic pneumonias are caused by very contagious agents, the etiology must be correctly determined in order to administer appropriate patient care. [ncbi.nlm.nih.gov]

Viral etiology and epidemiology of acute respiratory infections in children in Nairobi, Kenya. Am J Trop Med Hyg 1988 ;39:632-40. [ Links ] 20. Lina B., Valette M., Foray S., et al. [scielo.br]

H., Parainfluenza 2 (CA) virus: Etiologic association with croup, Pediatrics 28 :614–621 (1961). PubMed Google Scholar 51a. KINGSBURY, D. W., BRATT, M. A., CHOPPIN, P. W., HANSON, R. [link.springer.com]

The epidemiologic relatedness of hPIV-3 strains was investigated by sequencing of the haemagglutinin-neuraminidase and fusion protein genes. [ncbi.nlm.nih.gov]

This work demonstrates the promise of mNGS for providing rapid information for infection prevention in addition to microbial detection. [ncbi.nlm.nih.gov]