Presentation
If there is a significant degree of suspiciousness or paranoia present, people may be very reluctant to discuss these issues with a stranger. There is a broad spectrum to the nature and severity of symptoms that may be present at any one time. [psychcentral.com]
Gender and cultural differences in presentation Schizophrenia presents itself three to six years later in women than in men, but it presents itself the same way between genders. [courses.lumenlearning.com]
Another criterion present in patients with paranoid schizophrenia are auditory hallucinations, in which the person hears voices or sounds that are not really present. [dictionary.cambridge.org]
[…] voices or sounds that are not really present. [en.wikipedia.org]
The hallucinations experienced in cases of schizophrenia may involve seeing, hearing, smelling, feeling or even tasting something that is not actually present. [news-medical.net]
Entire Body System
- Malnutrition
Environmental : Scientists believe that prenatal exposure to toxins, maternal malnutrition, or viruses may lead to the development of schizophrenia. Additionally, birth trauma may increase the risk for developing the disorder. [pacificgrovehospital.com]
Other factors that may contribute are: a viral infection in the mother while she was pregnant malnutrition before birth stress, trauma, or childhood abuse problems during delivery Stressful experiences often occur before a diagnosis of schizophrenia. [medicalnewstoday.com]
In addition, other negative prenatal and perinatal situations, such as stress, infection, malnutrition, maternal diabetes and other medical conditions, can be associated with schizophrenia. [exploringyourmind.com]
Risk Factors : Children with older fathers are more susceptible Family history of mental illness Difficult birth, especially if the individual experienced lack of oxygen during birth Malnutrition during fetal development Stress, infections, or maternal [covingtonbh.com]
[…] factors Although the precise cause of schizophrenia isn't known, certain factors seem to increase the risk of developing or triggering schizophrenia, including: Having a family history of schizophrenia Some pregnancy and birth complications, such as malnutrition [mayoclinic.org]
- Weakness
These include changes in: self-care sleeping or eating patterns weakness lack of energy headaches changes in school or work performance strange sensations confused, strange, or bizarre thinking that gets expressed as bizarre behavior The actual break [gulfbend.org]
Instead, it’s important to recognize an individual’s specific strengths and weaknesses, he says. [spectrumnews.org]
Clozapine, perhaps the most effective antipsychotic agent, is a particularly weak dopamine D2 antagonist. Thus, other neurotransmitter systems, such as norepinephrine, serotonin, and gamma-aminobutyric acid (GABA), are undoubtedly involved. [emedicine.medscape.com]
- Fatigue
There’s a risk of side effects, such as: dizziness drowsiness and fatigue dry mouth low blood pressure nausea vomiting uncontrollable movements vision changes weight gain Sometimes, your doctor may prescribe other medications to treat other symptoms. [healthline.com]
He developed fatigue, fever and shortness of breath, and it turned out he had a cancer of the blood called acute myeloid leukemia. He’d need a bone-marrow transplant to survive. After the procedure came the miracle. [nytimes.com]
Omega-3 fatty acids from fatty fish, fish oil, walnuts, and flaxseeds can help improve focus, banish fatigue, and balance your moods. [helpguide.org]
- Unconsciousness
Freud's suggestion 5 that in males paranoid psychotic symptoms develop as a defense against emerging unconscious homosexual wishes had generally been regarded as proven in the absence of controlled verifying studies. [jamanetwork.com]
Psychiatrical
- Auditory Hallucination
The defining feature of the paranoid subtype is the presence of auditory hallucinations or prominent delusional thoughts about persecution or conspiracy. [psychcentral.com]
Delusions and auditory hallucinations predominate in patients with this subtype of Schizophrenia while their affective and cognitive functioning remain relatively intact. Old criteria for this diagnosis. See Also: paranoia (stuttering glossary) [behavenet.com]
The clinical picture is dominated by relatively stable, often paranoid, delusions, usually accompanied by hallucinations, particularly of the auditory variety, and perceptual disturbances. [schizophrenia.com]
It is also common for hallucinations to be related to the delusional theme. “The main characteristics of paranoid schizophrenia are clear delusions or auditory hallucinations.” [exploringyourmind.com]
It is associated with delusions and auditory hallucinations. The delusions tend to involve fear of unfair persecution or of being a famous person like Paris Hilton or Michael Jordan. [sharecare.com]
- Disorganized Behavior
Disorganized speech in this disorder is not the same as a speech impairment. Disorganized behavior Disorganized behavior refers to an overall inability to control your behavior across contexts, such as at home and work. [healthline.com]
Disorganized Schizophrenia Disorganized type, which is marked by disorganized speech, behavior, and flattened affect is particularly disruptive. [healthcommunities.com]
Symptoms There are five types of symptoms characteristic of schizophrenia: delusions, hallucinations, disorganized speech, disorganized behavior, and the so-called “negative” symptoms. [helpguide.org]
(295.1x) is characterized by disorganized speech, disorganized behavior, and flat or inappropriate affect. • Catatonic schizophrenia (295.2x) has predominate physical symptoms, including either immobility or excessive motor activity and the assumption [fortherecordmag.com]
These symptoms are the following: delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms. [exploringyourmind.com]
- Withdrawn
However, they often become withdrawn and antisocial. It’s important to be aware that some cases of schizophrenia do in fact cause violent outbursts. [seniorcaring.com]
Cognitive therapy may also counteract the fear of exposing limitations that makes some people with schizophrenia withdrawn and apathetic. [health.harvard.edu]
Common negative symptoms of schizophrenia include: Lack of interest or motivation Diminished emotional expression Changes in sleep patterns Becoming socially withdrawn Not caring about their appearance or hygiene Addiction and Schizophrenia Treatment [addictioncenter.com]
[…] this sub-type is no longer used in the United States since the 2013 change in the DSM-V that classifies the range of symptoms of former sub-types all under "schizophrenia". [2] Schizophrenia is defined as “a chronic mental disorder in which a person is withdrawn [en.wikipedia.org]
These and other symptoms often render the individual fearful, withdrawn, or difficult to interact with. Schizophrenia takes an enormous toll on afflicted families. [psychologytoday.com]
- Visual Hallucination
[…] form, such as whistling, humming, or laughing; hallucinations of smell or taste, or of sexual or other bodily sensations; visual hallucinations may occur but are rarely predominant. [schizophrenia.com]
Hallucinations of smell or taste, or of sexual or other bodily sensations; visual hallucinations may occur but are rarely predominant. [psychcentral.com]
I live with auditory and visual hallucinations, paranoia, and depression as a part of my disease. I ignore people sometimes. The other day one of my colleagues said good morning and I didn’t realize it until she was staring at me, waiting. [headspace.com]
Compared with schizophrenia symptoms in adults, teens may be: Less likely to have delusions More likely to have visual hallucinations When to see a doctor People with schizophrenia often lack awareness that their difficulties stem from a mental disorder [mayoclinic.org]
Along with delusions, there may be auditory hallucinations, or hearing things that are not there, and perceptual disturbances. Visual hallucinations sometimes occur. [medicalnewstoday.com]
- Delusion of Grandeur
Additionally, patients with paranoid schizophrenia may: Exhibit signs of great anxiety Be suspicious of new people Have delusions of grandeur (e.g., believe that they are more important to other people than they are) Have auditory hallucinations Isolate [dualdiagnosis.org]
"Delusion of grandeur", Psych Central Retrieved from http://psychcentral.com/encyclopedia/2008/delusion-of-grandeur/ ^ McLean, Duncan; Thara, Rangaswamy; John, Sujit; Barrett, Robert; Loa, Peter; McGrath, John; Mowry, Bryan (September 2014). [en.wikipedia.org]
Delusions of grandeur – Belief that you are a famous or important figure, such as Jesus Christ or Napoleon. Alternately, delusions of grandeur may involve the belief that you have unusual powers, such as the ability to fly. [helpguide.org]
Delusions of grandeur: You might believe that you have exceptional abilities, wealth, or importance. Delusions of persecution: This is the belief that everyone (or perhaps just one person) is out to get you. [healthline.com]
Neurologic
- Agitation
At least four of the following features are present in cases of paranoid personality disorder: Excessive reactions and agitation in response to perceived criticism Tendency to bear grudges Suspiciousness Combative and disproportionate regard for personal [news-medical.net]
— Matt Kawahara, SFChronicle.com, "Former Raiders player George Atkinson III dead at 27, reports say," 3 Dec. 2019 Betty had poorly controlled paranoid schizophrenia, and often called the clinic agitated, alternately whispering and screaming about government [merriam-webster.com]
They may be both rigid and motionless, or they may seem agitated and move around excessively, but always without external stimulus. [healthcommunities.com]
Steve’s First Appointment: A Potential Disaster The patient outcome manager who was doing his clinical interview was so alarmed by Steve’s psychotic behavior and intense agitation, she didn’t feel comfortable being alone in the same room with him. [amenclinics.com]
In addition, the various types of Schizophrenia are often characterized by other condition-specific symptoms, including the following: Catatonic Schizophrenia – negative emotions, rigid muscles, agitation, decreased ability to feel pain, and inability [disability-benefits-help.org]
- Catatonia
Undifferentiated Schizophrenia Undifferentiated schizophrenia is the type given to a lack of catatonia, paranoia, or disorganized speech. Undifferentiated schizophrenia might resemble other illnesses, including neurological disorders. [healthcommunities.com]
However, when at its height, it can lead to paranoia, delusions, and catatonia. It’s important to be prepared when your loved one’s schizophrenia reaches its height. 4. Plan Ahead Preparation is key when dealing with Paranoid Schizophrenia. [seniorcaring.com]
[…] of illness, that challenges can often be addressed, and that patients have many personal strengths that can be recognized and supported Related Conditions Schizoaffective disorder Delusional disorder Brief psychotic disorder Schizophreniform disorder Catatonia [psychiatry.org]
When catatonia lasts for hours, it becomes a medical emergency. Undifferentiated schizophrenia: The person has various vague symptoms. “They may not talk or express themselves much. They can be confused and paranoid,” says Dr. Bowers. [health.clevelandclinic.org]
Catatonia is a state in which a person does not move and does not respond to others. Catatonia is rare today, but it was more common when treatment for schizophrenia was not available. [psychologytoday.com]
- Perseveration
Finally, the catatonic type were those with increased motor symptoms (increased muscle tone and perseverance of posture). [en.wikipedia.org]
Perseveration – Repetition of words and statements; saying the same thing over and over. Clang – Meaningless use of rhyming words (“I said the bread and read the shed and fed Ned at the head”). [helpguide.org]
Workup
And did you do a mental status workup or question him about hallucinations or delusions? A. Yes. And what did you learn in that regard? A. Well, I focused on those issues twice. [pbs.org]
See Workup for more detail. Management Antipsychotic medications diminish the positive symptoms of schizophrenia and prevent relapses. There is no clear antipsychotic drug of choice for schizophrenia. [emedicine.medscape.com]
Treatment
When it comes to finding an effective paranoid schizophrenia treatment, it’s important to recognize that every patient is unique and will respond differently to each treatment option. [promisesbehavioralhealth.com]
Alex wants to see the same funding put into finding treatments for mental illness as there is for physical illness. [mqmentalhealth.org]
These symptoms assumedly cause a higher rate of intensive treatment in acute care wards. This difference in treatment context could also account for differences in infrastructure costs in the treatment of SAD patients. [journals.plos.org]
Early diagnosis is critical for the successful treatment of schizophrenia. [en.wikipedia.org]
Psychotherapy also plays an important role in the treatment of schizophrenia. [psycom.net]
Prognosis
Some authors contend that the prognosis for paranoid schizophrenia is fairly good, particularly if the onset is late and the symptoms relatively mild. Sources: Bayley, R. (1996) First person account: schizophrenia. [healthcentral.com]
“It both determines the appropriate treatment for the patient and provides the patient and family with an informed prognosis. [treatmentadvocacycenter.org]
What Is the Prognosis for Schizophrenia? The prognosis for people with schizophrenia can vary depending on the amount of support and treatment the patients receives. Many people with schizophrenia are able to function well and lead normal lives. [onhealth.com]
The prognosis is somewhat better than that for schizophrenia but worse than that for mood disorders. [fortherecordmag.com]
Usually the prognosis is poor because of the rapid development of "negative" symptoms, particularly flattening of affect and loss of volition. Hebephrenia should normally be diagnosed only in adolescents or young adults. [apps.who.int]
Etiology
Etiology Etiological factors for schizophrenia include genetic factors, environmental factors, and physiological factors. The more severe a parent’s schizophrenia, the more likely it is that a child will have schizophrenia. [courses.lumenlearning.com]
2015, 38% of a randomly selected sample of adult outpatients with schizophrenia (n=45) or schizoaffective disorder (n=5) was found to have comorbid SAD, as determined by a cutoff score of 29/30 on the total Liebowitz Social Anxiety Scale score. 3 The etiology [psychiatryadvisor.com]
Thus, inflammation might be related both to the psychopathology of schizophrenia and to metabolic disturbances seen in patients with schizophrenia. [12] Etiology The causes of schizophrenia are not known. [emedicine.medscape.com]
The rare work on this topic, however, supports the assumption that DD is not a genetic variant of PS. 37–39 Cardno and McGuffin, 8 overviewing the genetic research on DD, concluded that it is not clear whether there is a genetic contribution to the etiology [academic.oup.com]
Epidemiology
There is very little epidemiological data for Paranoid Schizophrenia specifically. When the diagnosis of Schizophrenia came in use, almost half were considered in the Paranoid category. [courses.lumenlearning.com]
However, there is a paucity of epidemiological studies on the prevalence of SAD. In particular, no epidemiological studies investigated the prevalence of SAD in Germany. [journals.plos.org]
Scientists at the NIH campus conduct research on numerous areas of study, including cognition, genetics, epidemiology, and psychiatry. The studies take place at the NIH Clinical Center in Bethesda, Maryland and require regular visits. [nimh.nih.gov]
Schizophrenia in Adults: Epidemiology and Pathogenesis. UpToDate. March 13, 2019. Schizophrenia: Questions and Answers About Psychosis. National Institute of Mental Health. Stone DM, Simon TR, Fowler KA, et al. [everydayhealth.com]
Translating the epidemiology of psychosis into public mental health: evidence, challenges and future prospects. J Public Ment Health. 2010 Jun. 9(2):4-14. [Medline]. Kety SS, Wender PH, Jacobsen B, et al. [emedicine.medscape.com]
Pathophysiology
Reciprocal links between impairments in LINE-1 methylation and neuro-immune and neuro-oxidative pathways may underpin the pathophysiology of both MIP and paranoid schizophrenia. Footnotes Assoc. [biorxiv.org]
The pathophysiology of SZ likely reflects genetic, developmental and environmental factors [ 3 ]. The main pathophysiological concept assumes an overstimulation of dopaminergic transmission in striatal, frontal and cingulate brain regions [ 3, 4 ]. [journals.plos.org]
Pathophysiology Anatomic, neurotransmitter, and immune system abnormalities have been implicated in the pathophysiology of schizophrenia. [emedicine.medscape.com]
Prevention
Thought disorder may be obvious in acute states, but if so it does not prevent the typical delusions or hallulcinations from being described clearly. [schizophrenia.com]
There's no sure way to prevent schizophrenia, but sticking with the treatment plan can help prevent relapses or worsening of symptoms. [mayoclinic.org]
Although medical records are often specific as to symptoms and resulting limitations, they often do not describe exactly how a condition prevents you from working, and therefore may not be sufficient for proving total disability according to the SSA. [disability-benefits-help.org]
Commentary Before discussing the clinical and ethical issues raised by Charlie’s current situation, we should reflect on the important distinction between preventive ethics (i.e., anticipating and preventing ethical problems before they arise) and reactive [journalofethics.ama-assn.org]
We’re funding multiple projects looking to improve understanding and treatment of schizophrenia, from looking at how it first develops in the brain to seeing if we could prevent it with folic acid . [mqmentalhealth.org]