We describe an extremely rare and previously unreported presentation of acute progressive paraparesis secondary to traumatic thoracic disc herniation in a child presenting to our institution. [ncbi.nlm.nih.gov]

Hepatospleenomegaly and mild neck stiffness were present. Fundoscopy was normal. He had spastic gait and could walk with assistance and support. DTR were hypertonic, sensory deficit present below twelfth thoracic vertebra. [scielo.br]

Presentation with rapid onset of paraparesis or quadriparesis (onset within 2 weeks) is rarer still. The authors present their experience in the management and outcome of patients with such a presentation. [thejns.org]

• Unable to Stand

  The patient was unable to stand on either leg alone and failed a trial of ambulation secondary to lower extremity weakness. Deep tendon reflexes were 2 + throughout. Sensation to touch, pinprick, and temperature was intact. [anesthesiology.pubs.asahq.org]

  Eight patients were unable to stand or walk and were bed bound at presentation. In 1 infant (aged 8 months) with paraparesis, the parents noticed paucity in limb movements, and another child older than 1 year could not walk, even with support. [thejns.org]

• Urinary Retention

  Complications such as eschars due to a prolonged decubitus, urinary retention to sphincter dysfunction, fractures, etc. make these patients potential surgery candidates. [scielo.org.co]

Therefore, upper endoscopy should be part of the diagnostic workup of vitamin B 12 deficiency. Multiple factors can lead to misdiagnosis of vitamin B 12 deficiency. [dovepress.com]

• Liver Biopsy

  Although clinical history appeared too long, we considered the hypothesis of IVLBCL on the basis of the laboratory constellation and proposed a liver biopsy, but the patient refused the procedure. The diagnosis was confirmed only at autopsy. [ncbi.nlm.nih.gov]

Our patient was a 41-year-old female, affected by PsA in treatment since 2 years with low-dose methylprednisolone and low-dose subcutaneous MTX. The treatment was effective. [ncbi.nlm.nih.gov]

Therefore, we now need the therapeutic regimens to protect the development, or be able to commence the treatments as soon as possible after the development safely and inexpensively even in long-term course or lifelong course of treatment. [eurekaselect.com]

Condition gradually improved as he could walk without help after three months of treatment, when further treatment was stopped. [scielo.br]

During the treatments I felt very relaxed and calm. Even though I hate needles acupuncture treatments are really OK. The clinic is quiet and the staff is friendly. [acupuncturerestoreshealth.com]

Prognosis HAM/TSP is a progressive disease, but it is rarely fatal. Most individuals live for several decades after the diagnosis. [brainfacts.org]

Prognosis Prognosis depends on the phenotype (pure/complex form), genotype, and is highly variable due to incomplete penetrance and variable gene expression. [orpha.net]

A further combination of valproic acid and zidovudine has demonstrated a decrease in proviral loads (in animals). [10] Prognosis [ edit ] The prognosis for Tropical spastic paraparesis indicates some improvement in a percentage of cases due to immunosuppressive [en.wikipedia.org]

Michaelis LS (1969) International inquiry on neurological terminology and prognosis in paraplegia and tetraplegia. Paraplegia 7:1–5 PubMed Google Scholar 24. [link.springer.com]

An intrahepatic portosystemic venous shunt (IPSVS) was observed on enhanced computed tomography, and hyperammonemia suggested leakage of neurotoxins from the shunt as the etiology of the patient's symptoms. [ncbi.nlm.nih.gov]

The association between human T-lymphotropic virus type I (HTLV-1) and TSP opened new vistas in its etiology and epidemology. [neurologyindia.com]

In addition to the above, signs and symptoms specific to the underlying etiology may also be present, e.g. headaches, diplopia, and bilateral visual defects in the case of a pituitary tumor. [medicaljoyworks.com]

Etiology The etiology is unknown but pancreatoblastoma can occur in any part of the pancreas. [orpha.net]

That this was not the true pathogenesis was shown by Sheehan in a series of papers.2-4 In these papers he proved that the etiology in cases developing post partum was that the blood supply of the gland after delivery is normally reduced rapidly. [annals.org]

How to use this case study General instructions : Case studies in applied epidemiology allow students to practice applying epidemiologic skills in the classroom to address real-world public health problems. [panafrican-med-journal.com]

Summary Epidemiology It has been described in affecting at least six male members spanning three generations of a large family. [orpha.net]

Epidemiology Congenital forms affect both sexes equally and are diagnosed early in childhood. The epidemiology of acquired or secondary forms depends on the underlying cause. [unboundmedicine.com]

Epidemiology of tropical spastic paraparesis in Colombia and associated HTLV-1 infection. Ann Neurol 1988;23:161-5. 11. Roman GC, Roman LN. [neurologyindia.com]

HSP data were compared to data from HUNT-3, a Norwegian epidemiological population study that enrolled more than 46,000 individuals. The survey was based on 19 items, each of which was also covered in HUNT3. [mdmag.com]

We review previously reported cases and current understanding of the pathophysiology of this complication. All cases had symptom onset several hours after the procedure. There seems to be a trend toward better outcomes with earlier treatment. [ncbi.nlm.nih.gov]

Pathophysiology Pathology is based on specific deficiency or deficiencies. [unboundmedicine.com]

It could be argued that the observed findings are an epiphenomenon, resulting from longstanding retrograde degeneration, rather than a direct reflection of the underlying TSP pathophysiology. [hippokratia.gr]

"Clinical Pathophysiology of Human T-Lymphotropic Virus-Type 1-Associated Myelopathy/Tropical Spastic Paraparesis". Frontiers in Microbiology. 3 : 389. doi : 10.3389/fmicb.2012.00389. PMC 3494083. PMID 23162542. ^ Ali, A (2006). [en.wikipedia.org]

Hypokalemic paralysis: a review of the etiologies, pathophysiology, presentation, and therapy. Am J Emerg Med. 1992; 10:143-8. 9.Magsino CH Jr, Ryan AJ Jr. Thyrotoxic periodic paralysis. [bjmp.org]

O Contractures: all joints need to be moved through their full range of movement to prevent contractures develop- ing. [books.mcai.org.uk]

Episodes can be prevented by achieving a euthyroid state. This report describes a young gentleman presenting with thyrotoxic hypokalemic paraparesis. [ncbi.nlm.nih.gov]

Tropical Spastic Paraparesis - Get information and read articles on Tropical Spastic Paraparesis sign, symptoms, causes, treatment, prevention and diagnosis at onlymyhealth.com, your complete health guide. [onlymyhealth.com]

Their prognosis improves if they take steps to prevent urinary tract infection and skin sores, and if they participate in physical and occupational therapy programs. [brainfacts.org]

[…] encouraging the adoption of primary and secondary preventive measures. [clinical.diabetesjournals.org]