Presentation
Nicotinic receptors are present at the ganglia of both the sympathetic and parasympathetic arms of the ANS as well as on the adrenal medulla. [pharmacologyeducation.org]
Present in neuromuscular junction, N M Agonist: Phenyl Trimethyl Ammonium Antagonist: Tubocurarine b. Present in autonomic ganglia, adrenal medulla, N N Agonist: Dimethyl phenyl piperazinium Antagonist: Hexamethonium Classification A. [howmed.net]
A SEMINAR ON PARASYMPATHOMIMETIC AGENTS Presented By: Ms. Kirti Vadi 17MPHCT002 M.Pharm (pharmacolgy) Rpcp,changa Guided By: Dr. Jalpa Suthar Assistant Professor Dept. Of Pharmacology & Toxicology Rpcp,changa 2. [slideshare.net]
[…] prostate gland of the dog is relatively more sensitive to direct-acting agents such as acetyicholine, methacholine and oxotremorine than to indirect-acting substances like physostigmine and neostigmine, and this conclusion is discussed in relation to present [jpet.aspetjournals.org]
Revised throughout, this new edition presents the latest guidance in clinical examination, randomized trials, medical treatment, laser therapy, and surgical procedures. [books.google.de]
Skin
- Increased Sweating
sweating, salivation, and gastric secretion Nausea Ocular symptoms: miosis, lacrimation CNS -related symptoms: restlessness, anxiety, ataxia, tremor possibly culminating in coma Musculoskeletal symptoms: fasciculations, weakness ;, spasms, paralysis [amboss.com]
(lacrimation, sweating, salivation, GI secretions) ADR: Nausea, vomiting, increased sweating and salivation S timulation followed by depression in CNS ADR: Delirium Classification: 1. [medchrome.com]
Systemic side-effects noted are: bradycardia, increased sweating, diarrhoea, excessive salivation and anxiety. [ikeyes.blogspot.com]
Neurologic
- Waddling Gait
Symptoms, which vary in type and severity, may include asymmetrical ptosis (a drooping of one or both eyelids), diplopia (double vision) due to weakness of the muscles that control eye movements, an unstable or waddling gait, weakness in arms, hands, [authorstream.com]
Treatment
These studies have used placebo [ 9, 11 - 15, 17 ], no treatment [ 8, 10 ] or other active treatments [ 16 ] as control, and involved 19–1796 patients. There was considerable heterogeneity in treatment methods ( Table 1 ). [onlinelibrary.wiley.com]
Treatments with some immunosuppressives take weeks to months before effects are noticed. [authorstream.com]
The use of an anxiolytic agent was not effective in the treatment of postoperative urinary retention. Bladder distention may increase the incidence of urinary retention. [ncbi.nlm.nih.gov]
Authored by three prominent specialists in the field, this text provides comprehensive coverage of diagnostic and treatment modalities for optimal glaucoma management. [books.google.de]
Prognosis
PMID: 7914443 Prognosis Schmetterer L, Strenn K, Findl O, Breiteneder H, Graselli U, Agneter E, Eichler HG, Wolzt M Clin Pharmacol Ther 1997 May;61(5):583-95. doi: 10.1016/S0009-9236(97)90138-7. [ncbi.nlm.nih.gov]
Prognosis Most patients with glaucoma retain useful vision for most of their lives if caught early and treatment is initiated. Incidence of unilateral blindness has been reported to be 27% and bilateral blindness 9% at 20 years following diagnosis. [eyewiki.aao.org]
Etiology
[from MeSH ] Etiology Clin Auton Res 1994 Apr;4(1-2):5-13. PMID: 7914443 Gottesman L, Milsom JW, Mazier WP Dis Colon Rectum 1989 Oct;32(10):867-70. [ncbi.nlm.nih.gov]
Atropine may also lessen the degree of partial heart block when vagal activity is an etiologic factor. In some individuals with complete heart block, the idioventricular rate may be accelerated by atropine; in others, the rate is stabilized. [rxlist.com]
Epidemiology
Synthesizes a classical approach to the glaucomas-based on seven earlier editions spanning over 40 years-with the most up-to-date evidence-based and epidemiologically-derived classifications and outcomes.Coherently correlates with authoritative consensus [books.google.de]
Pathophysiology
Multiple system atrophy: clinical aspects, pathophysiology, and treatment. Neurol Clin 1984; 2 : 487–498. PubMed Google Scholar 10. Cohen J, Low P, Feaket R, Sheps J, Jiang N-S. [link.springer.com]
Other possible risk factors include: perfusion pressure, coronary artery disease, diabetes, myopia Pathophysiology Not entirely understood. [eyewiki.aao.org]
Pathophysiologic changes in the optic nerves of eyes with primary open angle and pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci. 2005 Nov. 46(11):4170-81. [Medline]. Kanthan GL, Mitchell P, Burlutsky G, Rochtchina E, Wang JJ. [emedicine.medscape.com]
Prevention
DISCUSSION Taken together the currently available data show little if any beneficial effect of parasympathomimetic agents in preventing or treating UUB. [onlinelibrary.wiley.com]
Drug Names bethanechol, edrophonium, Prostigmin / neostigmine, Eserine / physostigmine, Mestinon / pyridostigmine Common uses myasthenia gravis, nondepolarizing neuromuscular blockade, postoperative bladder distention, postoperative ileus Pharmacology prevent [everything2.com]
Cholinesterase inhibitors act indirectly by preventing the enzyme from hydrolyzing (inactivating) acetylcholine at the receptor site. [chemistry.elmhurst.edu]
Encyclopedia Natural or synthetic Anti-glaucoma Agents relieve or prevent glaucoma, a condition characterized by increased intraocular pressure, excavation, and optic nerve damage. [tititudorancea.com]