Presentation
Acinic cell adenocarcinoma typically presents as a solitary and unfixed mass that may appear bluish. Up to 3% of cases appear bilaterally. More than one in three patients with this tumor present with pain. [clinicaladvisor.com]
Differential Diagnosis Individuals presenting with a salivary mass should be investigated for sialoliathiasis, chronic sialedenitis, autoimmune disease, and lymphoproliferative disorders. [teachmesurgery.com]
Clinical presentation The clinical presentation of parotid gland cancers is similar to that of benign parotid gland tumours. Most patients present with a painless palpable mass in the parotid or submandibular gland. [ncbi.nlm.nih.gov]
We present a case of OGCT accompanied with carcinoma ex pleomorphic adenoma in the parotid gland of a 67-year-old Korean female. [jpatholtm.org]
Clinical presentation [ edit ] The tumor is usually solitary and presents as a slow growing, painless, firm single nodular mass. Isolated nodules are generally outgrowths of the main nodule rather than a multinodular presentation. [en.wikipedia.org]
Treatment
Four patients (Nos. 1, 5, 6, and 7; Table ) received their initial treatment at an outside institution. [jamanetwork.com]
Selecting further treatment depends on many factors, including the specific cancer, prior treatment, site of recurrence, and individual patient considerations. [cancer.gov]
Adenoid cystic carcinoma can also recur many years after treatment. [teachmesurgery.com]
MRI provides superior soft tissue delineation such as perineural invasion when compared to CT only. [5] Treatment [ edit ] Overall, the mainstay of the treatment for salivary gland tumor is surgical resection. [en.wikipedia.org]
At all stages, patients should have access to a multidisciplinary team with expertise in the treatment of head and neck tumours. [ 11 ] Most current treatment depends on local ablation. [patient.info]
Prognosis
Springer, Berlin Seifert G (1997) Diagnosis and prognosis of salivary gland tumors. [med-college.de]
[…] health have better prognosis compared with those with poor health Age of the individual: Older individuals generally have poorer prognosis than younger individuals Individuals with bulky disease have a poorer prognosis Involvement of the lymph node can [dovemed.com]
Prognosis Prognosis for salivary gland tumours is depended on the pathology. Benign tumours have excellent outcome although pleomorphic salivary adenomas could recur especially if there is any tumour spillage during surgery. [teachmesurgery.com]
Prognosis The prognosis of carcinoma ex PA depends on its extension. [atlasgeneticsoncology.org]
prognosis tends to be good. [ 21 ] [patient.info]
Etiology
[…] and Pathophysiology Etiology and pathophysiology not fully understood; certain pathways and oncogenes have been implicated: p53, Bcl-2, PI3K/Akt, MDM2, VEGF, HGF, and ras. [unboundmedicine.com]
Warthin's tumor Rare histologic subtypes References: [5] [7] [8] [9] Malignant tumor Malignant salivary gland tumors are referred to collectively because of their many etiological, epidemiological, and pathological similarities. [amboss.com]
Role of Epstein-Barr virus and cytomegalovirus in the etiology of benign parotid tumors. Head Neck 2002;24:443-50. 13. Zohreh JA, Mohammad JA, Maryam M. Salivary gland tumors. A clinicopathologic study of 366 cases - Iran population. [jdas.in]
Discussion The etiology of the malignant transformation of the epithelial component of Warthin’s tumor remains unclear. [nature.com]
SC etiology is unknown, but the male-to-female ratio is 3:5. The patients often present with a painless, slow-growing, asymptomatic swelling, but some experience pain, and a few cases with facial paralyses have been reported. [karger.com]
Epidemiology
Background: The aim of this paper was to know the epidemiological characteristics of the salivary gland tumors in a Mexican population. Methods: A descriptive, retrospective and cross-sectional study was performed. [ncbi.nlm.nih.gov]
Warthin's tumor Rare histologic subtypes References: [5] [7] [8] [9] Malignant tumor Malignant salivary gland tumors are referred to collectively because of their many etiological, epidemiological, and pathological similarities. [amboss.com]
Epidemiology 2002;13:356. 8 Atula T, Grenman R, Klemi P et al (1998) Human papillomavirus, Epstein-Barr virus, human herpesvirus 8 and human cytomegalovirus involvement in salivary gland tumours. [headandneckcancerguide.org]
Epidemiology Incidence 1.5/100,000 cases in individuals in the United States 700 deaths annually Median age Benign: 45 years Malignant: 60 years Gender predilection Benign: female male Malignant: male female Prevalence Make up 6–8% of all head and neck [unboundmedicine.com]
Lymphomas may occasionally present in a salivary gland. [ 3 ] Epidemiology [ 4 ] The majority of salivary neoplasms are benign (65-70%). Nearly 80% of parotid gland tumours are benign. [patient.info]
Pathophysiology
Etiology and pathophysiology not fully understood; certain pathways and oncogenes have been implicated: p53, Bcl-2, PI3K/Akt, MDM2, VEGF, HGF, and ras. [unboundmedicine.com]
Prevention
Kerosene-cooking fuel exposure Nitrosamine exposure in rubber workers Early menarche and nulliparity General Prevention Cessation of tobacco and alcohol use -- To view the remaining sections of this topic, please sign in or purchase a subscription -- [unboundmedicine.com]
Current medical research has not established a method of preventing the formation of Carcinoma Ex Pleomorphic Adenoma of Salivary Gland Regular medical screening at periodic intervals with blood tests, radiological scans, and physical examinations, are [dovemed.com]
It also contains antibodies and other substances that help prevent infections of the mouth and throat. The 2 main types of salivary glands are the major salivary glands and minor salivary glands. [cancer.org]
Intraoperative frozen-section analysis can also help guide the extent of the surgery to prevent undertreatment. All efforts should be made to preserve the facial nerve. [jamanetwork.com]
[…] sensitivity varies in the range from 64% to 94%. [6], [7], [8] However, the sensitivity in detecting CXPA on FNA is lower and has been reported to be as low as 29%. [9] The low sensitivity is mostly attributed to sampling error and may subsequently prevent [cytojournal.com]