Treatment is based on the signs and symptoms present in each person. For more information, visit GARD. [rarediseases.org]

Both patients had unbalanced karyotypes, with duplication of the distal third of the short arm of chromosome 2, resulting from the same balanced reciprocal translocation present in both mothers: der(2), t(2;7)(p23;q36) mat. [jamanetwork.com]

When trisomy 2 mosaicism is detected during early pregnancy with chorionic villus sampling (CVS ), the affected cells may be confined only to the placenta, and not present in the fetus. [rarediseases.info.nih.gov]

In conclusion, chromosomal abnormality should be considered in children presenting with history of developmental delay and dysmorphic features. R. [hindawi.com]

Although the latter hypothesis is much less probable, it can not be rejected at the present time. [onlinelibrary.wiley.com]

• Sparse Eyebrows

  On physical examination, she was found to have microcephaly, open fontanelles, a prominent forehead, a flat occiput, hypertelorism, sparse eyebrows, a small nose with a depressed nasal bridge, a bulging philtrum, a thin upper lip, a high arched palate [ncbi.nlm.nih.gov]

• Depressed Nasal Bridge

  On physical examination, she was found to have microcephaly, open fontanelles, a prominent forehead, a flat occiput, hypertelorism, sparse eyebrows, a small nose with a depressed nasal bridge, a bulging philtrum, a thin upper lip, a high arched palate [ncbi.nlm.nih.gov]

  The eyebrows may be sparse and a depressed nasal bridge may be present, with a broad nasal tip and the nose itself may be short. [rarediseases.org]

Treatment is based on the signs and symptoms present in each person. For more information, visit GARD. [rarediseases.org]

What is the treatment for trisomy 18? The treatment and management of children with Edwards syndrome is dependent upon the severity of findings. [medicinenet.com]

Prognosis Trisomy 2 may define a distinct subtype of MDS, which in combination with further clonal chromosomal changes gives rise to AML. Further cases need to be collated to substantiate this. [atlasgeneticsoncology.org]

Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. Cytogenetic analysis in patients with primary myelodysplastic syndromes in leukaemic transformation. [atlasgeneticsoncology.org]

National Birth Defects Prevention Network. Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol. 2010;88:1008-16. [labtestsonline.it]

Treatment may also include measures to help prevent or aggressively treat respiratory infections. Other treatment is symptomatic and supportive. Early intervention is important to ensure that children with trisomy 5p reach their potential. [rarediseases.org]