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Pasteurella Multocida


Presentation

  • Additionally, the diagnostic challenge presented by this case report emphasizes the need for vigilance and thoroughness in obtaining histories from patients presenting with seemingly benign complaints, especially in vulnerable populations, such as infants[ncbi.nlm.nih.gov]
  • The patient presented with fever, right groin pain and malaise.[ncbi.nlm.nih.gov]
  • We present a case of PM empyema in a penicillin allergic 56-year-old female who has a history of contact with domestic cats and is known to have chronic obstructive pulmonary disease and a chronic history of smoking.[ncbi.nlm.nih.gov]
  • The present case illustrates a severe articular infection caused by this bacterium, leading to septic shock, in an elderly, otherwise healthy woman, after a simple scratch of a cat.[ncbi.nlm.nih.gov]
  • We present the first reported case of a patient who developed a postoperative sternal wound infection due to P. multocida complicated by bloodstream infection. The outcome was favorable following surgical debridement and antimicrobial therapy.[ncbi.nlm.nih.gov]
Lymphadenopathy
  • […] information 1 BMBCh, MRCP, MSc, Queen's Medical Centre, Department of Microbiology, Derby Road Nottingham, Nottingham NG7 2UH, United Kingdom. vanessawong@doctors.org.uk Abstract Kikuchi disease is a rare condition characterized by fever and persistent lymphadenopathy[ncbi.nlm.nih.gov]
  • It can also infect other locales, such as the respiratory tract, and is known to cause regional lymphadenopathy (swelling of the lymph nodes). In more serious cases, a bacteremia can result, causing an osteomyelitis or endocarditis.[en.wikipedia.org]
Intermittent Fever
  • Furthermore, a brain MRI, performed to investigate a persistent intermittent fever even if CSF became sterile, showed a focus cerebritis in the right parietal lobe, early stage of the cerebral abscess.[ncbi.nlm.nih.gov]
Productive Cough
  • The case is reported of an 82-year-old male who presented with a productive cough, fever, and shortness of breath, and who was initially diagnosed with pneumonia.[ncbi.nlm.nih.gov]
  • An 87-year-old man was admitted to hospital because of fever, productive cough, dyspnea and altered consciousness. His medical history was significant for chronic obstructive pulmonary disease. He owned several pets.[ncbi.nlm.nih.gov]
Sore Throat
  • A 52-year-old gentleman developed a sore throat and died suddenly within an hour of seeing his general practitioner. Post-mortem findings were consistent with death due to laryngeal obstruction associated with epiglottitis and laryngopharyngitis.[ncbi.nlm.nih.gov]
Suprapubic Pain
  • A 50-year-old sexually inactive woman presented with suprapubic pain and fever. Cat scratches were seen on her hand. Ultrasonography showed a 7.9-cm complex cystic adnexal structure. Her fever persisted despite broad-spectrum parenteral antibiotics.[ncbi.nlm.nih.gov]
Purpura
  • We found no case reports of purpura fulminans caused by Pasteurella infections in our literature review.[ncbi.nlm.nih.gov]
Hyperactivity
  • Consequently, the expression levels of JAK2 are increased, eventually leading to hyperactivity of JAK2 and its target, the transcription factor STAT3.[ncbi.nlm.nih.gov]

Workup

Pericardial Effusion
  • Purulent pericarditis is a rare entity, defined as the presence of neutrophilic pericardial effusion which is infected by a bacterial, fungus or parasite agent.[ncbi.nlm.nih.gov]
Helicobacter Pylori
  • Abstract The concept that bacterial infection could cause cancer has only recently become accepted because of the strong epidemiological and molecular evidence for a major carcinogenic role played by Helicobacter pylori.[ncbi.nlm.nih.gov]

Treatment

  • Our findings show that there is usually a history of exposure to the animal, early appearance of cat bite related infections, and multifactorial decision making for the treatment of P. multocida joint infections.[ncbi.nlm.nih.gov]
  • Despite treatment, the outcome was unfavourable and complicated by a corneal perforation. CONCLUSIONS: The prognosis of postoperative PM endophthalmitis remains poor, despite adequate treatment of the infection.[ncbi.nlm.nih.gov]
  • The fever subsided four days after treatment with intravenous ceftriaxone and the patient was discharged in a very good clinical condition after two weeks of treatment.[ncbi.nlm.nih.gov]
  • Treatment with ceftriaxone resulted in rapid resolution of the peritonitis and restoration of the patient.[ncbi.nlm.nih.gov]
  • We describe the successful treatment of an individual with P. multocida bacteremia secondary to tunnelled line infection managed with line retention.[ncbi.nlm.nih.gov]

Prognosis

  • CONCLUSIONS: The prognosis of postoperative PM endophthalmitis remains poor, despite adequate treatment of the infection. A history of recent pet exposure should alert physicians to this possible aetiological factor.[ncbi.nlm.nih.gov]
  • Prognosis Once a bacterial infection is halted, the bite victim usually recovers fully. There is no known cure for rabies once symptoms become evident and death is almost certain.[web.archive.org]

Etiology

  • The etiology of Pasteurella multocida must be borne in mind in cases of sepsis in immunodeficient individuals, such as the cirrhotic patient, as well as exposure to domestic animals.[ncbi.nlm.nih.gov]
  • Due to the polymicrobial etiology of P. multocida infections, treatment requires the use of antimicrobials targeted at the elimination of both aerobic and anaerobic, Gram-negative bacteria.[en.wikipedia.org]
  • A narrow focus on etiology of MMEs could fail to elucidate causation, where this involves multifactorial interactions between pathogens, hosts, and environment.[advances.sciencemag.org]

Epidemiology

  • Abstract The concept that bacterial infection could cause cancer has only recently become accepted because of the strong epidemiological and molecular evidence for a major carcinogenic role played by Helicobacter pylori.[ncbi.nlm.nih.gov]
  • No epidemiologic links between patients were found. Three had known pet exposure.[ncbi.nlm.nih.gov]
  • Hodgson , BSc, PhD, MBA 1 Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, near Edinburgh EH26 0PZ Biomathematics and Statistics Scotland, Kings Buildings, Edinburgh EH9 3JZ Epidemiology Research Unit, Scottish Agricultural College[veterinaryrecord.bmj.com]
  • View Article PubMed Google Scholar Uttenthal A, Jensen NPB, Blom JY: Viral aetiology of enzootic pneumonia in Danish dairy herds: Diagnostic tools and epidemiology. Vet Rec. 1996, 139: 114-117.[doi.org]
Sex distribution
Age distribution

Prevention

  • These infections must be regarded as preventable through adequate measures of hygiene.[ncbi.nlm.nih.gov]
  • Recently, rifaximin, a non-absorbable antibiotic which is used to prevent recurrent hepatic encephalopathy, has been proposed as effective prophylaxis for SBP. Here, we present an unusual case of SBP under treatment with rifaximin.[ncbi.nlm.nih.gov]
  • These cases demonstrate the importance of the prevention of close contact between pet animals and immunocompromised hosts such as post-chemotherapy neutropenic patients.[ncbi.nlm.nih.gov]
  • This rare disease could be prevented by reducing contact between infants and household pets, and by performing simple hygiene measures before handling babies.[ncbi.nlm.nih.gov]
  • Bacterial testing of PLTs is critical in the prevention of transfusion-acquired sepsis and allows the identification and treatment of asymptomatic bacteremic donors.[ncbi.nlm.nih.gov]

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