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Peanut Allergy

Allergy to Peanuts


Presentation

  • The results of the present study showed that the late introduction of peanuts to children increases the risk of developing a peanut allergy.[ncbi.nlm.nih.gov]
Fatigue
  • People infected with the seasonal flu virus feel miserable with fever, chills, muscle aches, coughing, congestion, headache and fatigue for a week or so.[niaid.nih.gov]
Developmental Disabilities
  • Disabilities, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA. 19 Division of Allergy-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. 20 Telethon Kids Institute[ncbi.nlm.nih.gov]
Stridor
  • These 23 children had at least one of the following responses: bronchospasm (6 children), stridor (1 child), altered level of consciousness (3 children), vomiting (8 children), urticaria (14 children), angioedema (7 children), rhinitis (17 children),[dx.doi.org]
  • Epinephrine must be administered promptly at the first warning symptoms, such as itching or swelling of the lips or mouth, tightening of the throat or nausea, and before respiratory distress, stridor or wheezing occur.[web.archive.org]
Nausea
  • Symptoms of peanut allergy includes skin reactions such as hives, itching around the mouth and throat, diarrhea, stomach cramps, nausea, vomiting, shortness of breath, wheezing and, in severe cases, anaphylaxis — a medical emergency.[reuters.com]
  • Symptoms can include hives, breathing difficulties, watery eyes, circulatory problems, nausea and vomiting, through to severe anaphylactic shock. It is diagnosed on the basis of a dietary and symptom log as well as skin examinations and blood tests.[3pauly.de]
  • Mild symptoms include sneezing or an itchy or runny nose; an itchy mouth; a few hives or mild itching; and mild nausea or stomach discomfort.[myhealth.alberta.ca]
  • They can include: itchy skin hives a tingling feeling in the mouth or throat a runny nose or congestion nausea anaphylaxis — a life-threatening reaction that can cause trouble breathing, swelling in the throat, fainting, dizziness and a drop in blood[childrenshospital.org]
Abdominal Pain
  • He was brought to our hospital owing to pruritus, cough, wheezing, and abdominal pain, which developed about one hour after eating a biscuit with peanuts. We diagnosed him as having anaphylaxis.[ci.nii.ac.jp]
  • It can lead to abdominal pain, vomiting or diarrhoea. In some cases, the airways are affected and allergic rhinitis or asthma symptoms can develop. The skin may also develop allergic reactions.[ecarf.org]
  • Other common reactions involve: swelling of the lips, eyes or face; abdominal pain; vomiting; and diarrhoea.[mydr.com.au]
  • Physical symptoms of allergic reaction can include itchiness, hives, swelling, eczema, sneezing, asthma, abdominal pain, drop in blood pressure, diarrhea, and cardiac arrest.[en.wikipedia.org]
  • Twenty‐one out of 24 patients reported reactions; 85 per cent of those were mild and resolved with antihistamines (abdominal pain 28%, oropharyngeal pruritus 27% and lip pruritis 11%) and three reactions were severe and resolved with epinephrine.[doi.org]
Eczema
  • For children with mild-to-moderate eczema, peanut can be introduced at 6 months, without the need for specialist evaluation.[ncbi.nlm.nih.gov]
  • This association was not explained by the fact that children with eczema and allergies tend to be given soy milk as compared to other children.[bristol.ac.uk]
  • […] and who had had eczema themselves in the first six months of life).[dx.doi.org]
Headache
  • Food Allergy Triggers It's common to have a bad reaction to foods we eat on occasion, such as gas from eating beans or headaches from drinking wine. If you're lactose intolerant you may experience diarrhea when you consume dairy.[medicinenet.com]
  • People infected with the seasonal flu virus feel miserable with fever, chills, muscle aches, coughing, congestion, headache and fatigue for a week or so.[niaid.nih.gov]
  • Conclusions: Epipen raised the systolic pressure more than did the Epipen Jr, but also caused more side effects (palpitations or other cardiovascular effects, with headache and nausea, beside the usual tremor, pallor and anxiety).[web.archive.org]

Treatment

  • IgE and IgE-antibodies to peanut and its components were analysed before treatment.[ncbi.nlm.nih.gov]
  • We did not include studies which investigated OIT in combination with another treatment if the effect of OIT could not be evaluated independently from the additional treatment.[doi.org]

Etiology

  • ETIOLOGY OF PEANUT ALLERGIES Food allergy prevalence has reportedly doubled in recent decades, with a significant increase also seen in allergy severity. 6 Allergies involving eggs, nuts, fish, milk, and other foods represent the leading cause of hospital-treated[mdedge.com]
  • Todd, Etiology of Type 1 Diabetes, Immunity, 32, 4, (457), (2010). A M Scurlock, B P Vickery, J O'B Hourihane and A W Burks, Pediatric food allergy and mucosal tolerance, Mucosal Immunology, 10.1038/mi.2010.21, 3, 4, (345-354), (2010). D.-A.[dx.doi.org]
  • It is a review on food-induced anaphylaxis, its prevalance, proposed etiology, a discussion on exercise-induced anaphylaxis that may be triggered by specific foods, at times not, an attempt at identification of specific food antigens responsible, and[web.archive.org]

Epidemiology

  • A good understanding of the epidemiology of this illness is necessary for treatment and prevention.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology, clinical characteristics, diagnostic test, case management, and natural history are reviewed.[ncbi.nlm.nih.gov]
  • Wesley Burks, Pathophysiology of Food Allergy, Pediatric Clinics of North America, 58, 2, (363), (2011).[dx.doi.org]
  • 2 66%; P .009). 29 Largely on the basis of the results of the LEAP trial, an expert panel recently advised peanut introduction as early as 4 to 6 months of age in infants at high risk (presence of severe eczema and/or egg allergy). 31 Given that the pathophysiology[doi.org]

Prevention

  • A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy.[ncbi.nlm.nih.gov]
  • N Engl J Med 348, 977 – 985. 13 Arshad, SH, Bateman, B, Sadeghnejad, A, et al. ( 2007 ) Prevention of allergic disease during childhood by allergen avoidance: The Isle of Wight Prevention Study.[doi.org]
  • Because peanut allergy is common and can be quite serious, many parents want guidelines for how to best prevent allergies to peanuts. Many research studies over the past 20 years have focused on peanut allergy and how best to prevent it.[jamanetwork.com]

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