A rigorous clinical and laboratory evaluation and an expert opinion from a hematopathologist are ideal. [archivesofpathology.org]

Outline, continued     Recognize the need for evaluation of supraclavicular lymph node enlargement Identify the chest x-ray as an important part of the initial evaluation of the patient with an unexplained lymphadenopathy Know that overwhelming sepsis [slideshare.net]

[…] marrow transplantation.6 Advanced stage disease with extranodal involvement at presentation is uncommon in children, but when present appears to correlate with a poor prognosis.3–5,8,9 Winberg et al4 found involvement of bone, lung, pleura, gonads, meninges [archivesofpathology.org]

Alternatively this specific testicular disease might be dependent on epidemiological factors that are less prevalent in western Europe. [haematologica.org]

[…] unknown, although certain risk factors were recently documented, including genetic factors, immune abnormalities, individual susceptibility, lifestyle, environmental exposures, as well as various infections caused by bacteria, viruses, mycoplasma and chlamydia [spandidos-publications.com]