Presentation
The work was presented as part of a mini oral presentation at the Annual Meeting of the American Society for Radiation Oncology (ASTRO) in Chicago this week. [medicalxpress.com]
[…] tumor is not possible Stage II GI tract lymphoma typically is limited to one segment of the gut plus or minus the associated mesenteric nodes only and the primary tumor can be completely removed grossly by segmental excision If marrow involvement is present [pathologyoutlines.com]
The age at presentation ranged between 2 and 15 years, with a mean standard deviation (SD) of 6.1 2.8 years and a male:female ratio of 1.7:1. Abdominal involvement was the most common presentation (73.2%). [spandidos-publications.com]
The work focuses on gemcitabine and brentuximab vedotin and is being presented as part of a poster presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting next month in Chicago. Dr. [cinj.org]
We used staining for CD5 to highlight small, reactive T cells, present in the interfollicular areas and within some neoplastic follicles. [haematologica.org]
Entire Body System
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Rigor
A rigorous clinical and laboratory evaluation and an expert opinion from a hematopathologist are ideal. [archivesofpathology.org]
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Sepsis
Outline, continued Recognize the need for evaluation of supraclavicular lymph node enlargement Identify the chest x-ray as an important part of the initial evaluation of the patient with an unexplained lymphadenopathy Know that overwhelming sepsis [slideshare.net]
Neurologic
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Meningism
[…] marrow transplantation.6 Advanced stage disease with extranodal involvement at presentation is uncommon in children, but when present appears to correlate with a poor prognosis.3–5,8,9 Winberg et al4 found involvement of bone, lung, pleura, gonads, meninges [archivesofpathology.org]
Urogenital
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Testicular Disease
Alternatively this specific testicular disease might be dependent on epidemiological factors that are less prevalent in western Europe. [haematologica.org]
Workup
Twenty-six patients who had been diagnosed with NHL during this period were identified, and data regarding clinical features, diagnostic and staging workup, and treatment outcomes were collected. [ijmpo.org]
(See Prognosis and Workup.) [1, 2] Massive mediastinal T-lymphoblastic lymphoma. Note compression of the left mainstem bronchus and the pulmonary atelectasis. [emedicine.medscape.com]
Microbiology
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Chlamydia
[…] unknown, although certain risk factors were recently documented, including genetic factors, immune abnormalities, individual susceptibility, lifestyle, environmental exposures, as well as various infections caused by bacteria, viruses, mycoplasma and chlamydia [spandidos-publications.com]
Treatment
We treat newly diagnosed patients, as well as patients referred to us from other centers to continue treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment or that have relapsed. [cityofhope.org]
– Pediatric and young adult patients whose Hodgkin lymphoma has recurred or is resistant to initial treatment can achieve remission and even cure with secondary treatments. [cinj.org]
Trials are often designed to treat a certain stage of cancer, either as the first form of treatment offered, or as an option for treatment after other treatments have failed to work. [oncolink.org]
BMT is a treatment that is an essential part of therapy for many patients with relapsed or refractory (treatment resistant) lymphoma. [mhealth.org]
Your child will need follow-up care during and after treatment to: Check on your child's response to the treatment Manage the side effects of treatment Look for returning or spreading cancer With treatment, most children with NHL go on to live long lives [urmc.rochester.edu]
Prognosis
Prognosis FAVORABLE: 10cm; B symptoms; 26. [slideshare.net]
Given the unusually favorable prognosis of PTNFL, it is critical that the diagnosis be recognized by pathologists and clinicians to prevent overtreatment. [hematology.org]
Prognosis Prognosis is similar to other indolent lymphomas, with excellent progression free and overall survival. [atlasgeneticsoncology.org]
The histologic features of classic FL and demonstration of B-cell clonality in at least some cases help confirm that these testicular follicular lesions are true malignant lymphomas, even if the patients seem to do very well.7 PROGNOSIS AND TREATMENT [archivesofpathology.org]
The overall prognosis for children with non-Hodgkin lymphoma has steadily improved. [emedicine.medscape.com]
Etiology
Incidence and Etiology Hodgkin’s 5% of childhood cancers Bimodal peaks, at 15-35 and 50; rare 5 M:F ratio of 3:1; variation r/t geography and SES, and type Increased in immunologic disorders, HIV, EBV 22. [slideshare.net]
Etiology In industrialized countries, most individuals with non-Hodgkin lymphoma have no known etiology or association. [emedicine.medscape.com]
However, the possible reasons of geographic differences in the spectrum of lymphoma remain unknown, mainly due to the etiology of lymphoma being largely unknown, although certain risk factors were recently documented, including genetic factors, immune [spandidos-publications.com]
The etiology is unknown but potential lymphomatogenic risk factors include 4 : viral infection, e.g. EBV, HTLV-1, HIV, HCV, HSV bacterial infection, e.g. [radiopaedia.org]
Epidemiology
The present study describes the epidemiological and clinical characteristics of 142 Egyptian pediatric NHL patients admitted to two Pediatric Oncology Units. [spandidos-publications.com]
This review will serve to update the readership on pediatric lymphoma epidemiology and known predisposition factors, clinical presentation, diagnostic tests, and therapeutic options, as well as treatment-related side effects that may need to be recognized [pedsinreview.aappublications.org]
Jude Children’s Research Hospital Departments of Epidemiology and Cancer Control and Computational Biology. [ascopost.com]
Epidemiologic data suggest that certain human leukocyte antigen (HLA) types, and even certain blood types, may increase or decrease the likelihood of developing non-Hodgkin lymphoma. [4, 5] Findings from several epidemiologic studies suggest that pesticide [emedicine.medscape.com]
Epidemiology Pediatric-type follicular lymphoma is a rare disease with incidence estimates of approximately 5% of all childhood lymphomas (O'Suoji et al., 2016). [atlasgeneticsoncology.org]
Pathophysiology
This reclassification was based on fundamental differences between the two diseases. [4] PTFL differs from follicular lymphoma in its clinical manifestations, its pathophysiology including the genomic alterations (i.e. chromosome abnormalities and gene [en.wikipedia.org]
Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity. Exp Cell Res. 2014; 325 (1):10–7. [ PubMed ] [ Google Scholar ] 105. Zhang K, Biroschak J, Glass DN, et al. [ncbi.nlm.nih.gov]
Prevention
They can be used to evaluate medications or treatments to prevent cancer, detect it earlier, or help manage side effects. Clinical trials are extremely important in furthering our knowledge of disease. [oncolink.org]
The researchers described factors that contribute to this “survivorship gap” in children and adolescents with HL, which they framed in terms of primary and secondary prevention strategies to minimize late effects. [hematologyadvisor.com]
We offer long-term follow-up services for preventive health care, including screenings and ongoing surveillance. [dukehealth.org]
Once bound, these antibodies prevent cell proliferation and induce cell death through a variety of mechanisms. [hopkinsmedicine.org]
Given the unusually favorable prognosis of PTNFL, it is critical that the diagnosis be recognized by pathologists and clinicians to prevent overtreatment. [hematology.org]