Presentation
Clinical presentation and confirmation of recurrence Patients with recurrent cervical cancer after radiation therapy usually present with bleeding, hematuria, or pelvic pain. [8] In some cases, the first sign of recurrence is the discovery of hydronephrosis [emedicine.medscape.com]
Immuno-compromised and elderly patients do not present typically for many of the diagnoses described above. [cancertherapyadvisor.com]
In Stage 0, cancer cells are present on the top layer of the cervix only. They have not gone into deeper layers of the cervical tissue or other organs. The remaining stages are called invasive cancer. [acog.org]
You will be alone in the examination room during the CT scan, unless due to specific circumstances you require someone present. The radiographer will always be able to see, hear and speak with you through a built-in intercom system. [materprivate.ie]
Reassurance from the physician should be provided to alleviate patient fears that a more serious condition is present. [fascrs.org]
Entire Body System
- Weight Loss
Systemic symptoms such as fever, chills, night sweats, weight loss, appetite changes. Surgical history. Adhesions may be causing the pain or may represent another post-operative complication. Recent trauma. [cancertherapyadvisor.com]
Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and (rarely) leakage of urine or feces from the vagina. [23] Bleeding after [en.wikipedia.org]
- Fatigue
Stop if you have any pain, discomfort, fatigue (feeling more tired or weak than usual), or swelling. Here is a video that shows you how to do these exercises and stretches. [mskcc.org]
Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and (rarely) leakage of urine or feces from the vagina. [23] Bleeding after [en.wikipedia.org]
- Anemia
Endometriosis: Sx: Pelvic pain, dysmenorrhea, dyspareunia, rectal pain with bleeding (if bowel invasion) Labs: CBC (blood loss anemia) Imaging: Ultrasound is of limited value since cysts cannot be differentiated from neoplasm. [cancertherapyadvisor.com]
2006, the US Food and Drug Administration approved the use of a combination of two chemotherapy drugs, hycamtin and cisplatin, for women with late-stage (IVB) cervical cancer treatment. [84] Combination treatment has significant risk of neutropenia, anemia [en.wikipedia.org]
- Pathologist
The pathologist’s report includes the type of cancer, the number of lymph nodes removed and the number of lymph nodes that have cancer cells. [cancer.ca]
These results are what a pathologist might report from a biopsy. These should not be confused with the Bethesda system terms for Pap test ( cytopathology ) results. [en.wikipedia.org]
- Burning Pain
A growth on the prostate, whether benign or cancerous, may also cause pelvic pain or discomfort. 17. Urinary tract infection (UTI) The typical symptoms of a UTI are burning pain during urination and more frequent urges to urinate. [medicalnewstoday.com]
Gastrointestinal
- Nausea
[…] endometriosis from pelvic inflammatory disease Pregnancy: Sx: Amenorrhea, nausea and vomiting, breast tenderness, urinary frequency and urgency Labs: Urine pregnancy test, urinalysis, CBC, serologic testing for syphilis, rubella, varicella, Rh type, [cancertherapyadvisor.com]
Some symptoms of pelvic mass may include: Pelvic pain (most comon) Swelling or a bloated feeling of the abdomen Frequent urination due to pressure on the bladder Nausea and or vomitting Pelvic Mass Causes Some of the most common causes of a pelvic mass [hoag.org]
A person should seek medical help immediately if the pain is severe or they experience nausea or vomiting, fever, or loss of consciousness. It is best to contact a doctor with any questions or concerns about new or chronic pelvic pain. [medicalnewstoday.com]
- Abdominal Pain
[…] differential Imaging: Abdominal Ultrasound (assess for urinary retention) Pyelonephritis – symptoms usually persist for Sx: Dysuria, hematuria, flank pain, abdominal pain, fever, urinary urgency/frequency, nausea, vomiting Labs: Leukocytosis with left [cancertherapyadvisor.com]
[…] in the lower belly (abdominal) area Unexplained infertility (usually only done after ultrasound) Unexplained pelvic pain (usually only done after ultrasound) This test may be done if a male has any of the following signs or symptoms: Lumps or swelling [medlineplus.gov]
- Loss of Appetite
Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and (rarely) leakage of urine or feces from the vagina. [23] Bleeding after [en.wikipedia.org]
Musculoskeletal
- Back Pain
PID causes pelvic or low back pain, menstrual period changes, and unusual vaginal discharge. 6. Ovulation pain Ovulation pain or "mittelschmerz," is slight to moderate discomfort during the middle part of a menstrual cycle. [medicalnewstoday.com]
low back pain, vaginal discharge, fever, rash, abnormal uterine bleeding, RUQ pain (perihepatitis) Labs: Urine Pregnancy Test, Urinalysis, NAAT/Endocervical Culture for GC/CT, STD screening (HIV, syphilis), microscopy of vaginal secretions (> 15 wbcs [cancertherapyadvisor.com]
Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and (rarely) leakage of urine or feces from the vagina. [23] Bleeding after [en.wikipedia.org]
- Low Back Pain
PID causes pelvic or low back pain, menstrual period changes, and unusual vaginal discharge. 6. Ovulation pain Ovulation pain or "mittelschmerz," is slight to moderate discomfort during the middle part of a menstrual cycle. [medicalnewstoday.com]
low back pain, vaginal discharge, fever, rash, abnormal uterine bleeding, RUQ pain (perihepatitis) Labs: Urine Pregnancy Test, Urinalysis, NAAT/Endocervical Culture for GC/CT, STD screening (HIV, syphilis), microscopy of vaginal secretions (> 15 wbcs [cancertherapyadvisor.com]
Urogenital
- Pelvic Pain
Causes Constipation, endometriosis, fibroids, and STIs can cause pelvic pain. There are many causes of pelvic pain, including: 1. Constipation Constipation can cause pelvic pain, especially if it affects the lower colon. [medicalnewstoday.com]
PELVIC PAIN SYNDROMES Chronic pelvic pain can be seen in up to 11% of men and 12% of women, and results in 10% of the total visits to gynecologists. There are a number of types of pelvic pain syndromes, which will be discussed further. [fascrs.org]
Or your doctor might recommend a pelvic exam if you have symptoms such as unusual vaginal discharge or pelvic pain. A pelvic exam usually lasts only a few minutes. [mayoclinic.org]
Eur Radiol (2016). doi: 10.1007/s00330-016-4600-3. http://link.springer.com/article/10.1007/s00330-016-4600-3 Acute abdominal and pelvic pain in pregnancy: ESUR recommendations. G. Masselli, L. Derchi, J. McHugo, A. Rockall, P. Vock, M. Weston, J.A. [esur.org]
- Urinary Urgency
[…] differential Imaging: Abdominal Ultrasound (assess for urinary retention) Pyelonephritis – symptoms usually persist for Sx: Dysuria, hematuria, flank pain, abdominal pain, fever, urinary urgency/frequency, nausea, vomiting Labs: Leukocytosis with left [cancertherapyadvisor.com]
- Renal Insufficiency
Laboratory tests Complete blood count (leukocytosis indicating infection, HELLP, ectopic pregnancy, Hbg/Hct -blood loss anemia) Basic metabolic profile (renal insufficiency, BUN:creat ratio may suggest pre-renal versus renal versus post renal etiology [cancertherapyadvisor.com]
- Flank Pain
tender prostate during rectal exam Labs: Urinalysis, Urine culture, CBC with differential Imaging: Abdominal Ultrasound (assess for urinary retention) Pyelonephritis – symptoms usually persist for Sx: Dysuria, hematuria, flank pain, abdominal pain, [cancertherapyadvisor.com]
Neurologic
- Irritability
Pelvic pain may have multiple causes, including: Inflammation or direct irritation of nerves caused by injury, fibrosis, pressure, or intraperitoneal inflammation Contractions or cramps of both smooth and skeletal muscles Some of the more common sources [hopkinsmedicine.org]
First, your doctor looks at your vulva, checking for irritation, redness, sores, swelling or other abnormalities. Internal visual exam. [mayoclinic.org]
Laparoscopy is the confirmatory and therapeutic procedure Cystitis: Sx: Irritative voiding symptoms (frequency, urgency, dysuria), afebrile, pain with a full bladder Labs: Urinalysis, Urine Culture, Blood culture, CBC with differential, Syphilis, HIV, [cancertherapyadvisor.com]
These include: irritable bowel syndrome ulcerative colitis diverticulitis 3. Endometriosis Endometriosis is when tissue similar to the uterine lining grows outside of the uterus. [medicalnewstoday.com]
Make sure the stockings don’t cause any irritation or leave marks on your skin. It’s best if your lymphedema therapist fits you with the stockings so you can be sure they fit well. We recommend wearing light compression stockings. [mskcc.org]
Workup
[…] frequency, urgency, dysuria), afebrile, pain with a full bladder Labs: Urinalysis, Urine Culture, Blood culture, CBC with differential, Syphilis, HIV, Endocervical culture Imaging: Abdominal Ultrasound or cystoscopy in men as it is rare and warrants workup [cancertherapyadvisor.com]
Treatment
The preferred citation for this PDQ summary is: PDQ® Adult Treatment Editorial Board. PDQ Transitional Cell Cancer of the Renal Pelvis and Ureter Treatment. Bethesda, MD: National Cancer Institute. Updated. [cancer.gov]
They use the stage along with other information about the type and grade of the cancer to make treatment decisions and give a prognosis. Depending on the result, your doctor will decide if you need more tests, any treatment or follow-up care. [cancer.ca]
Treatment Options Because numerous disorders can lead to the formation of a pelvic mass, it’s important to diagnose the cause of the mass before an appropriate treatment plan can be determined. [hoag.org]
The mainstay of treatment is biofeedback therapy. [fascrs.org]
Prognosis
Talk to your doctor about your prognosis. [cancer.ca]
501 genes associated with favourable prognosis. [proteinatlas.org]
The latter category indicates a more pervasive tumor diathesis and generally a less favorable prognosis. [cancer.gov]
Besides the T-stage, the proximity of tumor to mesorectal fascia also affects the prognosis in cases of rectal cancer as tumor within 1 mm of this fascia, also known as circumferential resection margin (CRM) is associated with significantly increased [colorectal-cancer.imedpub.com]
Etiology
Additionally, it is the preferred imaging modality when a gynecologic etiology is suspected. [cancertherapyadvisor.com]
"Postcoital bleeding: a review on etiology, diagnosis, and management". Obstetrics and Gynecology International. 2014 : 192087. doi : 10.1155/2014/192087. PMC 4086375. PMID 25045355. ^ Dunne, EF; Park, IU (Dec 2013). [en.wikipedia.org]
Epidemiology
Surveillance Epidemiology and End Results (SEER). Bethesda, MD: National Cancer Institute; 2002: http://seer.cancer.gov/. [cancer.ca]
“Sexually transmitted diseases, pelvic inflammatory disease, and infertility: an epidemiologic update”. Epidemiol Rev. vol. 12. 1990. pp. 199-220. Donaldson, CK. “Acute Gynecologic Disorders”. Radiol Clin North Am. vol. 53. 2015 Nov. pp. 1293-307. [cancertherapyadvisor.com]
"Epidemiologic classification of human papillomavirus types associated with cervical cancer". N. Engl. J. Med. 348 (6): 518–27. doi : 10.1056/NEJMoa021641. hdl : 2445/122831. [en.wikipedia.org]
Pathophysiology
“Sleisenger & Fordtran's Gastrointestinal and liver disease: pathophysiology, diagnosis, management”. 2010. Copyright © 2017, 2013 Decision Support in Medicine, LLC. All rights reserved. [cancertherapyadvisor.com]
Prevention
Food and Drug Administration (FDA) approved the first preventive HPV vaccine, marketed by Merck & Co. under the trade name Gardasil. [en.wikipedia.org]
Food and Drug Administration approved a vaccine which prevents infection by the HPV 16 and 18. Studies have shown that the vaccine appears to prevent precancerous lesions and early-stage cervical cancer. [proteinatlas.org]
How can I prevent human papillomavirus infection? A vaccine is available that can prevent infection with HPV. The vaccine protects against the HPV types that are the most common cause of cancer, precancer, and genital warts. [acog.org]
You may be given: antibiotics to prevent infection pain-relieving medicine instructions on caring for and dressing the wound information about how to manage the drainage bag and tube advice on how much and which types of activity you can do after surgery [cancer.ca]
Moisturize your skin often to prevent chapping and chaffing. Keep the area between your toes clean and dry to prevent infections. Don’t walk barefoot. Make sure your footwear fit you well to avoid blisters. [mskcc.org]