The children gave no history of prior movement disorders and there was no family history of movement disorders. [doi.org]

• Central Nervous System : Seizures, Tourette syndrome, hallucinations, movement disorder, night blindness, depression, dizziness, increased irritability, headache, drowsiness and sleeplessness. • Gastrointestinal : Loss of appetite, weight loss, nausea [medindia.net]

Adverse Reactions Central nervous system: Insomnia, dizziness, drowsiness, mental depression, increased irritability, seizures, precipitation of Tourette's syndrome, hallucinations, headache, movement disorders Dermatologic: Rash Endocrine & metabolic [syrianclinic.com]

Phenothiazines or butyrophenones may also be used especially for serious life-threatening symptoms, including hypertensive crisis and severe hyperthermia, although these serious complications of stimulant overdose have not been reported after pemoline [ncbi.nlm.nih.gov]

Ginsberg MD Hertzman M & Schmidt-Nowara WW (1970) Amphetamine intoxication with coagulopathy, hyperthermia and reversible renal failure. A syndrome resembling heatstroke. Ann Intern Med, 73: 81-85. [inchem.org]

Hyperthermia is best treated with external cooling measures, or when severe or unresponsive, muscle paralysis with pancuronium may be needed. [syrianclinic.com]

[…] and chemotherapy via magnetic-nanoconjugates US9351941B2 ( en ) * 2012-05-30 2016-05-31 National Cheng Kung University Radiofrequency-induced synchronization of in situ hyperthermia and chemotherapy via magnetic-nanoconjugates WO2014011603A1 ( en ) * [google.com]

The dependent measures included number of math problems completed correctly, teacher-recorded rates of on-task behavior and noncompliance, and teacher ratings on an Abbreviated Conners Teacher Rating Scale. [ncbi.nlm.nih.gov]

BACKGROUND: Historically, the field of self-injury has distinguished between the behaviors exhibited among individuals with a developmental disability (self-injurious behaviors; SIB) and those present within a normative population (nonsuicidal self-injury [ncbi.nlm.nih.gov]

fever large pupils muscle trembling or twitching restlessness sweating vomiting Pemoline may also cause the following side effects that your doctor will watch for: Rare Liver problems slow growth in children Some side effects may occur that usually do [drugs.com]

Bilateral cortical aspirations were performed in 3-5-week-old rats. One week postsurgery, a pemoline challenge was administered. Behavioral comparisons were completed between the lesion group and an anesthetized-only control group. [ncbi.nlm.nih.gov]

الصفحة 231 - Autopsy findings have usually revealed acute fulminating pneumonia or pneumonitis, aspiration of gastric contents, or intramyocardial lesions Although not a general feature of fluphenazine. potentiation of central nervous system depressants [books.google.com]

Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, itching, clay-colored stools, or dark urine. These symptoms may be early signs of liver damage. [drugs.com]

Diazepam consistently increased the duration of stereotyped behavior. It also reduced licking/biting and self-biting but the latter effects were not consistent. Pretreatment with PCA had negligible effects on stereotyped behavior. [ncbi.nlm.nih.gov]

The possibility of choreoathetoid movements should be considered in patients presenting after pemoline overdose [doi.org]

The possibility of choreoathetoid movements should be considered in patients presenting after pemoline overdose. [ncbi.nlm.nih.gov]

Adverse Effects Hepatic failure of dysfunction Choreoathetoid movements Other adverse effects similar to Methylphenidate Images: Related links to external sites (from Bing) Ontology: Pemoline (C0030800) Definition (NCI) An oxazolidine compound with central [fpnotebook.com]

Abstract Plasma pemoline levels were measured in 6- to 12-year-old, severely hyperactive males coincident with onset of abnormal involuntary movements. [ncbi.nlm.nih.gov]

Abstract Plasma pemoline levels were measured in 6- to 12-year-old, severely hyperactive males coincident with onset of abnormal involuntary movements. [ncbi.nlm.nih.gov]

Acute chorea in a child followed ingestion of pemoline mesylate. In guinea pigs, in an experimental model of chorea, chronic administration of pemoline induced behavioral supersensitivity to other dopaminergic agonists. [ncbi.nlm.nih.gov]

Power of the spontaneous EEG increased with time since sleep and amplitude of the P3 event-related response decreased. The changes may be interpreted as the reduction in alertness with time awake. [ncbi.nlm.nih.gov]

The second case, in an 11-year-old, developed hepatic failure with marked prolongation in prothrombin time nonresponsive to parenteral vitamin K, deep jaundice, and submassive hepatic necrosis. This patient had a long history of pemoline usage. [ncbi.nlm.nih.gov]

1991). 9.4.5 Hepatic Hepatitis and fatal acute hepatic necrosis have been described (Kalant & Kalant, 1975). 9.4.6 Urinary 9.4.6.1 Renal Renal failure, secondary to dehydration or rhabdomyolysis may be observed. 9.4.6.2 Other Increased bladder sphincter [inchem.org]

Other causes of fulminant liver failure were ruled out, and the liver biopsy was suggestive of drug toxicity. We estimated the probability that these three cases represent an increased risk of fulminant liver failure associated with pemoline. [ncbi.nlm.nih.gov]