Presentation
"Chancroid Clinical Presentation". News-Medical. https://www.news-medical.net/health/Chancroid-Clinical-Presentation.aspx. (accessed November 02, 2022). Harvard Meštrović, Tomislav. 2019. Chancroid Clinical Presentation. [news-medical.net]
A 30-year-old man presents with mildly painful sores that have been present on his penis for three days. He had no symptoms before the lesions appeared, and he has never had similar genital lesions before. [clinicaladvisor.com]
Special treatment situations Special considerations Seek specialist advice before treating any complicated presentation. Follow up Will be provided by specialist service. Test of Cure (TOC) Not required. [sti.guidelines.org.au]
The book covers the entire spectrum of HIV-associated cutaneous diseases, and emphasizes how they present in immunocompromised patients. [books.google.com]
Immune System
- Lymph Node Tenderness
Cervicitis: cervical erosion, mucopurulent discharge, pelvic pain or dyspareunia ( painful intercourse ) Endometritis or Salpingitis: Possible pain, abdomen tenderness, cervix, uterus, and lymph nodes tenderness. vaginal discharge, and or painful urination [med-help.net]
Entire Body System
- Inflammation
CONSUMERS: Click here for the Consumer Version Topic Resources Balanitis is inflammation of the glans penis, posthitis is inflammation of the prepuce, and balanoposthitis is inflammation of both. [merckmanuals.com]
Pulsatilla has long been known as a remedy for otitis externa or inflammation of the external... Pagina 64 - In alcoholic inebriation it promotes the appetite and digestion, and lessens the craving for liquor. [books.google.ro]
Terminology + Balanitis – inflammation of the glans penis + Posthitis – inflammation of the penile foreskin + Balanoposthitis – inflammation of both + Prepuce – foreskin. [dermcast.tv]
ICD-10-CM A57 is grouped within Diagnostic Related Group(s) (MS-DRG v 36.0): 727 Inflammation of the male reproductive system with mcc 728 Inflammation of the male reproductive system without mcc 742 Uterine and adnexa procedures for non-malignancy with [icd10data.com]
In women, an inflammation of the cervix, the fallopian tubes or/and peritonitis may appear as well as inflammation and infection of the lymphatic system. [courses.lumenlearning.com]
- Weakness
[…] is playing a role, check neck flexor strength to assess if a new neuromuscular weakness is present – MIF & VC are the confrontational tests for the diaphragm. [ucsfmed.wordpress.com]
This disease is commonly observed (and sporadically endemic) in the poorest regions of the world that have weak public health infrastructure (such as Asia, Africa and the Caribbean). [news-medical.net]
Hydrocortisone This is a weak steroid cream that can be used in region where is delicate and soft skin tissues like groin area. Apply the cream on the affected part of the penis directly according to the instruction given by the doctor. 4. [howtocure.org]
Rhinoscleroma, Klebsiella pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli : Enterotoxigenic Enteroinvasive Enterohemorrhagic O157:H7 O104:H4 Hemolytic-uremic syndrome Enterobacter aerogenes / Enterobacter cloacae Slow/weak [en.wikipedia.org]
- Infertility
Gonorrhea Gonorrhea is one of the most common STDs in the United States and can lead to infertility in men and women. [tlcclinic.center]
Injection and Other Drug Users 1061 Chapter 90 Sexually Transmitted Infections and Pregnancy 1079 Chapter 91 Sexually Transmitted Infections in Neonates and Infants 1095 Chapter 92 Congenital Syphilis 1103 Chapter 93 Sexually Transmitted Infections and Infertility [books.google.com]
If left untreated, chancroid can lead to female infertility due to secondary bacterial infections and chronic ulceration of the cervix or external genitalia. [familyfertilityplan.com]
Women are at risk of developing pelvic inflammatory disease (PID), while in men the infection can progress to epididymitis and cause infertility. [courses.lumenlearning.com]
- Constitutional Symptom
Primary genital herpes will present as numerous painful vesicles associated with constitutional symptoms such as fevers and myalgias. [epmonthly.com]
symptoms and regional lymphadenopathy. 3 Figure 1. [aafp.org]
[…] a number of factors, such as geographical area where sexual intercourse has taken place; socioeconomic factors; gender of sexual partners; number of partners; HIV status and local prevalence; drug use; commercial sex; and circumcision.Footnote 4 GUD constitutes [canada.ca]
Watch for signs of general lymphadenopathy; mild constitutional symptoms such as headache, malaise, anorexia, weight loss, nausea, vomiting, and sore throat. [med-help.net]
Regional lymphadenopathy and systemic constitutional symptoms may be present. [emedicine.medscape.com]
- Reiter Syndrome
’s syndrome, Behçet’s syndrome, fixed-drug eruption, and scabies). [clinicaladvisor.com]
J Urol 130:352–354 PubMed Google Scholar Weitzul S, Duvic M (1997) HIV-related psoriasis and Reiter’s syndrome. [link.springer.com]
Reactive Arthritis Reactive arthritis (formerly known as Reiter syndrome) is characterized by urethritis, arthritis, and ophthalmologic abnormalities that occur simultaneously or sequentially. [emedicine.medscape.com]
Chlamydia trachomatis serovars D-K cause urethritis, epididymitis, proctitis, conjunctivitis (ophthalmia neonatorum), cervicitis, endometritis, salpingitis, perihepatitis and Reiter’s syndrome. Discussed later in this handout. [atsu.edu]
Gastrointestinal
- Rectal Bleeding
Females with Chancroid may also experience symptoms such as pain during urination, vaginal discharge, pain when moving the bowels, or rectal bleeding. Both men and women can experience fevers and general tiredness with the illness. [seabhs.org]
Symptoms in women are often less noticeable and may be limited to painful urination or defecation, painful intercourse, rectal bleeding, or vaginal discharge. Chancroid can be treated effectively with several antibiotics. [medicinenet.com]
Others may not experience sores, but may develop symptoms such as vaginal discharge or rectal bleeding. How is chancroid treated? Chancroid is treated with antibiotics. If treatment is successful, the ulcers usually begin to improve within a week. [irishhealth.com]
- Rectal Discharge
Symptoms, which typically appear 2-14 days after exposure, include pain or burning during urination or defecation; a yellowish or greenish (pus-like) penile, vaginal, cervical, or rectal discharge; swelling and tenderness of the vulva; sore throat; and [thebody.com]
Skin
- Papule
These fine papules are small, asymptomatic lesions that develop after puberty in 10% to 15% of men. [mitchmedical.us]
Papule or ulcer Persistent, painful, beefy- Red Papule s or ulcers onset 2-3 months after exposure Necrosis or sclerosis may occur Behcet Sydrome Ulcer Recurrent oral ( Aphthous Ulcer ) and Genital Ulcers Genital Ulcers scar in more than half of cases [fpnotebook.com]
One colony-forming unit (cfu) of H. ducreyi results in papule formation in 50% of individuals. 90% develop papule with 100 cfu ( 3 ). [unboundmedicine.com]
Transient chancroid is a term for a tiny papule that is often overlooked, but characteristic lymphadenopathy is present. [news-medical.net]
Miscellaneous Benign Lesions of the Male Genital Tract Pearly Penile Papules Pearly penile papules are asymptomatic, grouped, white papules that develop in approximately 8-20% of males (see Pearly Penile Papules ). [75] They are benign and are not associated [emedicine.medscape.com]
- Erythema
Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome and erythema multiforme. Arch Dermatol '1993; 129: 92-6. [books.google.ro]
The characteristic presentation is a pruritic or burning, sharply circumscribed, round-to-oval patch with violaceous or dusky erythema. [aafp.org]
Buboes are usually located only on one side of the body and coupled with erythema of the superjacent skin. They sometimes spontaneously rupture and form inguinal sinuses. [news-medical.net]
The skin may be affected by erythema multiforme, urticaria, erythema nodosum or scarlatiniform rash. There may (rarely) be signs of conjunctivitis, hepatomegaly, meningoencephalitis, pericarditis, pneumonia and arthritis. [patient.info]
Neurologic
- Confusion
Terminology Dwarf chancroid: soft, painful, small ulcer Giant chancroid: may extend rapidly and be associated with ruptured inguinal abscess Phagedenic chancroid: may destroy external genitalia if superimposed Fusobacterium infection is present Do not confuse [pathologyoutlines.com]
Since symptoms of the infection can be confused with syphilis and herpes, your doctor will examine the discharge with a microscope. Chancroid can be treated with antibiotics to kill the bacteria that are causing the infection. [surgeonformen.com]
They should not be confused with condylomata acuminata. Figure 18-12 shows pearly penile papules. Figure 18-13 shows the penis of a patient with the chancre of primary syphilis. [mitchmedical.us]
- Irritability
Scabies can also result in itching of the penile shaft and head due to the constant irritation. The irritation and the agitation to scratch may increase at night. [howgetrid.org]
Irritation Coming into contact with certain irritants such as chemicals in detergents, exspecially those used in washing cloths can result in these lesions on the skin. 3. [howtocure.org]
Purpuric – Coumadin necrosis A: Allergic/Irritant/Other Dermatits Top Five Allergens: 1. Balsum of Peru(10.8%) 2. Frangrance mix (8.1%) 3. Tolu balsam (8.1%) 4. Phenylmercuric acetate (8.1%) 5. [dermcast.tv]
— This is an unproved remedy, but it has irritant properties like the other Ranunculaceae. Hansen gives as indications : " Pemphigus ; bullae are surrounded by a ring, much itching. On the third day they are transformed into crusts. [books.google.ro]
Urogenital
- Genital Lesions
Type-specific glycoprotein G serologic testing for HSV-2 can be considered if genital lesions are crusted or if direct testing of the lesion is negative. [clinicaladvisor.com]
The patient that presents with a single genital lesion can be a challenge to diagnose for the emergency physician. [epmonthly.com]
(C) The genital lesions of GI are painless, beefy red, raised lesions. (Part C from Al-Harmozi SA, el-Tonsy MH. Granulmoa inguinale. Report of the first case in Qatar. Sex Transm Dis1986;13:102, with permission.) Figure 107.4. Genital ulcers. [5minuteconsult.com]
- Vaginal Discharge
Females with Chancroid may also experience symptoms such as pain during urination, vaginal discharge, pain when moving the bowels, or rectal bleeding. Both men and women can experience fevers and general tiredness with the illness. [seabhs.org]
Symptoms in women are often less noticeable and may be limited to painful urination or defecation, painful intercourse, rectal bleeding, or vaginal discharge. Chancroid can be treated effectively with several antibiotics. [medicinenet.com]
Others may not experience sores, but may develop symptoms such as vaginal discharge or rectal bleeding. How is chancroid treated? Chancroid is treated with antibiotics. If treatment is successful, the ulcers usually begin to improve within a week. [irishhealth.com]
- Penile Lesion
The physical examination was normal except for the penile lesion. The patient denied any penile discharge and had one sexual partner who denied having any skin lesions or pruritus. [aafp.org]
Painful penile lesions are often sign of a sexually transmitted disease. Find Infectious disease-specialists near you Conditions that causes painful penile lesions includes Chancroid which is a bacterial infection. [zocdoc.com]
The following is a non-exhaustive (and likely with much overlap) summary of what we came up with: PAINFUL penile lesion Chancroid/H. ducreyi SJS/TEN drug lesion SCC Traumatic lesion/entrapment injury Ulcers in s/o foley HSV Paraphimosis PAINLESS penile [ucsfmed.wordpress.com]
Ulcerated Penile Lesions in Patient with Chancroid This photograph of a patient with chancroid shows three shallow ulcerated lesions that each have an erythematous base and a well-defined border. These lesions are typically painful. [std.uw.edu]
- Dyspareunia
And if this infected woman is having sex, she may have pain associated with intercourse, and that's referred to as dyspareunia, dyspareunia, so pain during sex. [khanacademy.org]
Women generally have less specific symptoms such as painful urination or pain on passing bowel motions (defaecation), vaginal discharge, painful sexual intercourse ( dyspareunia ) and rectal bleeding. [dermnetnz.org]
Cervicitis: cervical erosion, mucopurulent discharge, pelvic pain or dyspareunia ( painful intercourse ) Endometritis or Salpingitis: Possible pain, abdomen tenderness, cervix, uterus, and lymph nodes tenderness. vaginal discharge, and or painful urination [med-help.net]
Has irregular or ragged borders Has a base that is covered with a gray or yellowish-gray material Has a base that bleeds easily if traumatized or scraped painful swollen lymph nodes occurs in 30 to 60% of patients. dysuria (pain with urination) and dyspareunia [en.wikipedia.org]
- Painful Penile Lesion
Painful penile lesions are often sign of a sexually transmitted disease. Find Infectious disease-specialists near you Conditions that causes painful penile lesions includes Chancroid which is a bacterial infection. [zocdoc.com]
The following is a non-exhaustive (and likely with much overlap) summary of what we came up with: PAINFUL penile lesion Chancroid/H. ducreyi SJS/TEN drug lesion SCC Traumatic lesion/entrapment injury Ulcers in s/o foley HSV Paraphimosis PAINLESS penile [ucsfmed.wordpress.com]
Workup
For this reason, it must be seriously considered if the rest of the workup is negative. He should also be offered a HIV screening examination. Dependent on the laboratory capability, these test results may not be available in a timely fashion. [epmonthly.com]
Ped Clin North Am 48:1539–1557 CrossRef Google Scholar Mingin GC, Hinds A, Nguyen HT, Baskin LS (2004) Children with a febrile urinary tract infection and a negative radiologic workup: factors predictive of recurrence. [link.springer.com]
Colonoscopy
- Multiple Ulcerations
Multiple ulcers are common, particularly in women. Painful inguinal lymphadenitis occurs in 30% of patients, and lymph nodes may suppurate, become fluctuant and spontaneously rupture. [canada.ca]
Transient chancroid Superficial ulcers that may heal rapidly, followed by a typical inguinal bubo. Serpiginous chancroid Multiple ulcers that coalesce to form a serpiginous pattern. [en.wikipedia.org]
Treatment
Principal Treatment Options Situation Recommended Alternative Uncomplicated infection Azithromycin 1g PO, stat OR Ceftriaxone 500mg in 2mL of 1% lignocaine IMI, stat OR Ciprofloxacin 500mg PO, BD for 3 days Alternative regimens are not recommended Treatment [sti.guidelines.org.au]
Treatment of Chancroid Recommended antibiotic treatment of Chancroid: Azithromycin 1 g p.o. once Ceftriaxone 250 mg i.m. once Ciprofloxacin 500 mg p.o. 1-0-1 for 3 days Erythromycin 500 mg p.o. 1-1-1-1 for 7 days Resistance to antibiotic treatment is [urology-textbook.com]
You’ll also find expert guidance on new vaccines, screening techniques, treatment guidelines, and best practices in the field. [books.google.com]
Get clear, concise descriptions and evidence-based treatment guidelines for a full range of clinical conditions, ranging from the common to the unusual. [books.google.ro]
Treatment Of Skin Diseases. 2010. pp. 135-36. (A detailed description with references of first-, second- and third-line theraputic choices for treatment of chancroid.) “Sexually Transmitted Diseases Treatment Guidelines 2006”. [dermatologyadvisor.com]
Prognosis
Outlook (Prognosis) Chancroid can get better on its own. Some people have months of painful ulcers and draining. Antibiotic treatment often clears up the lesions quickly with very little scarring. [centurahealthinfo.org]
Prognosis In general, the outlook for patients presenting with secondary malignancy in the penis is very poor, irrespective of the site of primary and the type of therapy. [issoonline.biomedcentral.com]
Outlook (Prognosis) Chancroid can get better on its own. However, some people may have months of painful ulcers and draining. Antibiotic treatment usually clears up the lesions quickly with very little scarring. [indiatoday.in]
Etiology
Footnote 5 Diagnosis Clinical etiologic diagnosis is frequently erroneous; in Canada, careful etiologic investigation of an ulcer should be carried out, since chancroid is not known to be endemic. [canada.ca]
[…] superimposed Fusobacterium infection is present Do not confuse with chancre, a lesion typical of infection with syphilis Epidemiology Mainly in developing countries, particularly Africa, Asia and Latin America Associated with commercial sex workers Etiology [pathologyoutlines.com]
Etiology Pathogen of Chancroid: Haemophilus ducreyi : immobile gram-negative bacteria, oval cocci arranged in a chain. Signs and Symptoms Genital Ulcer: Chancroid leads to one or more deep purulent genital ulcer. [urology-textbook.com]
– probable traumatic Resolves with abstinence + May have temporal relation to an STD Dysesthetic Anogenital Syndrome + Abnormal sensation (tingling/burning/numbess/pruritus/pain) in anogenital area + Etiology: Neurogenic (CNS) Neuropathic (PNS) – Small [dermcast.tv]
Epidemiology
Abstract Chancroid, the most common cause of genital ulceration in Africa, is known to be associated epidemiologically with heterosexual transmission of human immunodeficiency virus (HIV). [ncbi.nlm.nih.gov]
Plummer FA, D’Costa LJ, Nsanze H, et al: Epidemiology of chancroid and Haemophilus ducreyi in Nairobi. Lancet 2 :1293–1295, 1983. PubMed CrossRef Google Scholar 10. [link.springer.com]
Effectively diagnose all types of STDs and HIV/AIDS with approximately 1,100 images—most in full color and more than 30% new to this edition―that depict the epidemiology as well as the clinical manifestations of these diseases. [books.google.com]
Overview MeSH Major Fluorodeoxyglucose F18 Neurofibromatosis 1 Positron-Emission Tomography abstract Chancroid, the most common cause of genital ulceration in Africa, is known to be associated epidemiologically with heterosexual transmission of human [vivo.med.cornell.edu]
Epidemiology of Haemophilius ducreyi infections. Emerg Infect Dis. 2016;22(1):1–8. Janowicz DM, Li W, Bauer ME. [5minuteconsult.com]
Pathophysiology
The pathophysiological mechanisms by which chancroid might facilitate the spread of HIV are obscure. [ncbi.nlm.nih.gov]
Pathophysiology Humans are the only known reservoir for S scabiei. [emedicine.medscape.com]
Background, Pathophysiology, Epidemiology. N.p., 09 Feb. 2017. Web. 16 Apr. 2017. Last Updated: 16 January 2018. [sexinfo.soc.ucsb.edu]
More common in Sub-Saharan Africa Southeast Asia Latin America Etiology and Pathophysiology Haemophilus ducreyi enters through abraded skin during sexual activity, attaching to susceptible cells. [unboundmedicine.com]
Prevention
Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 04 June 2015. Web. 16 Apr. 2017. "Chancroid." Background, Pathophysiology, Epidemiology. N.p., 09 Feb. 2017. Web. 16 Apr. 2017. Last Updated: 16 January 2018. [sexinfo.soc.ucsb.edu]
Prevention The best prevention for chancroid is to use a condom during sexual intercourse. Chancroid can also be prevented by abstinence (avoidance of any sexual contact) and by being in a monogamous relationship with a disease-free partner. [encyclopedia.com]
Some researchers have speculated that these products, designed for use prior to sexual intercourse to prevent infection, might also be used for postcoital or emergency STD prevention. [un.org]
Fig. from Public Health Image Library, Center for Disease Control and Prevention, USA, www.cdc.gov. [urology-textbook.com]