Presentation
We present in the current study, a patient who presented with progressive penile gangrene and skin necrosis due to CUA. [ncbi.nlm.nih.gov]
The case report presents the history and clinical images of a patient with diabetes and multiple medical co-morbidities who presented with bilateral lower extremity ulcerations and dry gangrene of the glans penis. [omicsonline.org]
The Pattern of Penile Gangrene in Sokoto, Nigeria Abstract Objective: To examine the presentation and outcome of management of penile gangrene. [ajol.info]
Entire Body System
- Enuresis
In the majority of patients, it is for erotic and autoerotic reasons 4,5,6,13, in children it may be placed by ignorant parents to prevent enuresis 4 and others due to psychosexual or psychiatric disorders 4. [ispub.com]
[…] article, diabetes was known as the leading predisposing systemic factor.[ 3 ] Fournier describes in anecdotes some of the misconceptions of the times that created this condition, including the practice of nighttime ligation of the prepuce to control enuresis [ncbi.nlm.nih.gov]
- Nightmare
WOMAN CONSCIOUS DURING SURGERY AFTER ANESTHESIA MISHAP: ‘THE NIGHTMARES HAVE BEEN HORRENDOUS’ The condition typically causes blood clots, skin ulcers, and can also lead to serious, potentially deadly infections such as gangrene, or the death of tissue [foxnews.com]
GETTY/BMJ HEALTH NIGHTMARE: A scan (right) shows how the patient's penis began to rot away (Pic: GETTY/BMJ) Ten days after his surgery, the patient was admitted to King George’s Medical University Hospital. [dailystar.co.uk]
- Arm Pain
Case A 65-year-old man presented with right arm pain after falling over. He had end-stage renal disease secondary to type II diabetes mellitus and had required haemodialysis for 1 year. [academic.oup.com]
- Intravenous Administration
Treatment and Outcome Treatment of Fournier gangrene includes hemodynamic stabilization and the intravenous administration of broad-spectrum antibiotics using multiple antimicrobial agents. [pubs.rsna.org]
Cardiovascular
- Left Ventricular Dysfunction
The parathormone was markedly raised at 425-pg/ml. 2D echocardiogram revealed mild left ventricular dysfunction. [indianjurol.com]
Workup
Serum
- Normocytic Anemia
Laboratory investigations at admission revealed polymorpholeukocytosis (white cell count, 17.5 x 10 9 /μL with 85.2% neutrophils) and normocytic anemia (Hb, 5.3 gm/dl and mean corpuscular volume, MCV, 90 fL), elevated sedimentation rate (120 mm/H [normal [annalsafrmed.org]
Microbiology
- Eikenella
Cases of monomicrobial Eikenella corrodens infection from a human bite have been found to cause a locally destructive lesion that was managed with local irrigation and broad spectrum antibiotics [6]. [hindawi.com]
Colonoscopy
- Multiple Ulcerations
There were multiple ulcerations and eschars over trunk and limbs [Figure 1]. A hard black eschar was noticed over the glans penis [Figure 2]. Foul smelling discharge was coming out of urethra and undersurface of penile lesion. [annalsafrmed.org]
Other Pathologies
- Diffuse Vasculitis
Secondary hyperparathyroidism may cause diffuse vasculitis and vascular calcification, which can lead to widespread ischemic necrosis and gangrene. [ncbi.nlm.nih.gov]
Treatment
Penile entrapment and subsequent strangulation is a serious injury that requires a prompt treatment to avoid gangrene. [ncbi.nlm.nih.gov]
Penile Gangrene due to Strangulation by a Metallic Nut: A Case Report Abstract BACKGROUND: Penile entrapment and subsequent strangulation is a serious injury that requires a prompt treatment to avoid gangrene. [ajol.info]
Prognosis
Comparison of the patients' ages, presentations, underlying diseases, the duration of conservative treatments, surgical options, resected penile length, and prognosis. All of the five patients underwent partial penectomy. [ncbi.nlm.nih.gov]
It is considered a urological emergency with a poor prognosis due to its high mortality rate (ranging ~15-50% 3 ). [radiopaedia.org]
The index case had multiple systemic illnesses and showed progression despite appropriate medical management portending a poor prognosis; he had sudden death probably due to acute cardiac event. 1. [indianjurol.com]
Despite the rarity of this disease, unfavorable prognosis related to this disease depends much on the timing of medical care. [karger.com]
Etiology
We concluded that this was a rare etiology of Fournier's gangrene and examined the complications of pelvic bone fracture in this context. Keywords: Etiology, foam, Fournier's gangrene, hematoma, osteomyelitis How to cite this article: Fang CL. [e-fjs.org]
The final chapter deals with the etiology, pathology, clinical diagnosis, and treatment of priapism. This book is a valuable resource for physicians. [books.google.it]
The etiologies could be infectious, traumatic, or vasculogenic. The treatment algorithm is controversial because of limited case numbers. [ncbi.nlm.nih.gov]
The main etiological factors were urethral stricture in 8 (50%) patients, associated with diabetes mellitus in 2 (13%), impacted urethral calculus in 3 (19%), circumcision in 2 (13%), priapism in sickle cell disease in 2 (13%) and trauma in 1 (6%). [ajol.info]
Epidemiology
Epidemiology of thrombosis in children with acute lymphoblastic leukemia. Thromb Res. 2003;111(3):125-31. Review. PMID:14678808 Athale U.H. & Chan AKC. [medresearch.in]
"Fournier's gangrene: Population based epidemiology and outcomes". The Journal of Urology. 181 (5): 2120–6. doi : 10.1016/j.juro.2009.01.034. PMC 3042351. PMID 19286224. [en.wikipedia.org]
Epidemiology Elderly adults (male and female), immunocompromised (particularly diabetes) or those with depressed mental status Sites Dartos and penile fascia are preferred sites Etiology 50 - 60% of infections have GI or GU source of infection Usually [pathologyoutlines.com]
However, understanding of the disease has changed with increasing elucidation on the epidemiology, causative organisms, and pathogenesis. [jcsjournal.org]
Ufimtseva MA, Malishevskaya NP, Syrneva TA: Clinical and epidemiological features of syphilis in the territories of the urals, siberia and the far east. Russian J Dermatovenereol 2009; 2: 68–73. Author Contacts Prof. M.A. [karger.com]
Pathophysiology
Reduction of paraphimosis: a technique based on pathophysiology. Br J Surg. 1996;83:1247. Copyright © 2000 by the American Academy of Family Physicians. This content is owned by the AAFP. [aafp.org]
Symptoms and Pathophysiology The etiology of, and predisposing factors for, FG provide a favorable environment for infection. [uspharmacist.com]
Pathophysiology The following are pathognomonic findings of Fournier gangrene upon pathologic evaluation of the involved tissue: Necrosis of the superficial and deep fascial planes, Fibrinoid coagulation of the nutrient arterioles, Polymorphonuclear cell [intechopen.com]
Abstract Despite advances in the evaluation, treatment, and pathophysiological understanding of necrotizing soft-tissue infections, Fournier's gangrene remains a life-threatening urological emergency. [nature.com]
In published reports, the factors affecting survival or death from FG were not clearly identified until the study of Laor and colleagues in 1995 (2), in which measurable pathophysiologic data between survivors and non survivors of FG were compared. [latunisiemedicale.com]
Prevention
We report a case of mycotic penile gangrene in a diabetic child to highlight its potentially preventable disastrous outcome. [ncbi.nlm.nih.gov]
It is usually associated with vascular insufficiency and amputation is required to prevent spread of infection from the necrotic tissue. [irep.iium.edu.my]
[…] the primary surgical treatment. 11 This case confirmed that penile gangrene is the disease which is followed by severe intoxication and predisposed to fast progression; Immediate surgical intervention with excision of the necrotizing tissues allows to prevent [slideplayer.com]
Prevention of the problem is best done by maintaining strict hygiene and frequent monitoring of the device. [urotoday.com]