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  • The literature on solitary brainstem abscesses was reviewed and an overview of the literature between January 1984 and May 2009 is presented.[ncbi.nlm.nih.gov]
  • Main Article Content Franco Giardini * Affiliation not present. Erika Savio Affiliation not present. Romolo Protti Affiliation not present. Cristina Pollino Affiliation not present. Tullio Albanesi Affiliation not present.[pagepressjournals.org]
  • We describe a 30-year-old female presenting with synovitis of the left 4th proximal interphalangeal joint. Anaerobic cultures of the synovial membrane grew Peptostreptococcus magnus. The synovitis resolved after a course of intravenous penicillin G.[ncbi.nlm.nih.gov]
  • A case of a destructive knee joint infection with rapid progress caused by P. micros is presented. The significance of the microbiological findings was initially not acknowledged, which contributed to a nonsuccessful clinical outcome.[ncbi.nlm.nih.gov]
  • We present a patient with prosthetic valve endocarditis caused by Finegoldia magna (formerly Peptostreptococcus magnus). Blood cultures in the BacT/ALERT and BACTEC 9240 system were negative.[ncbi.nlm.nih.gov]
Intravenous Drugs
  • Bacteriology of skin and soft-tissue infections: comparison of infections in intravenous drug users and individuals with no history of intravenous drug use . Clin Infect Dis 20 ( Suppl 2 ): S279 – S282 . 30. Brook I . 2004 .[asmscience.org]
  • Quantitative PCR showed a progressive fall in DNA concentration in nonviable cell pellets and a concomitant rise in DNA concentration in the supernatant. DNA staining showed that some air-killed cells retained an intact cell wall.[ncbi.nlm.nih.gov]
  • The phosphorylation of macrophage kinases, including cAMP-dependent protein-serine kinase (PKA) catalytic subunit beta, G protein-coupled receptor-serine kinase 2, mitogen-activated protein-serine kinase p38 alpha (p38a MAPK), extracellular regulated[ncbi.nlm.nih.gov]
  • None of the 60 pus aspirates analysed was positive for Peptostreptococcus magnus DNA. It is concluded that Peptostreptococcus magnus is not a major pathogen in adult periodontitis or dento-alveolar abscesses.[ncbi.nlm.nih.gov]
  • The PCR assay was then applied to the detection of P. anaerobius DNA in subgingival plaque samples from adult periodontitis patients and pus aspirates from subjects with acute dento-alveolar abscesses.[ncbi.nlm.nih.gov]
  • Obtaining appropriate culture specimens of these organisms requires the use of transtracheal aspiration, aspiration through double-lumen catheterization, or direct lung puncture.[emedicine.medscape.com]
  • Specimens like pus aspirates, soft tissue and body fluids were included in the study. P. anaerobius isolates were identified by standard methods and confirmed by automated mass spectrometry.[manipal.pure.elsevier.com]
  • Aspiration yielded Peptostreptococcus asaccharolyticus . This unusual case prompted a review of the clinical and microbiologic features of renal abscess in pediatric patients at our hospital over the past 10 years.[pediatrics.aappublications.org]
  • P. micros was isolated on PMM and identified biochemically and enzymatically from both adult periodontitis and early-onset periodontitis patients with higher percentages isolated from the diseased periodontal pockets of adult periodontitis patients; furthermore[ncbi.nlm.nih.gov]
  • To date, very little is known regarding the role of P. micros in periodontal disease. Therefore, a genetic analysis was initiated to differentiate among strains of P. micros infecting periodontal patients.[ncbi.nlm.nih.gov]
  • These results suggest that P. anaerobius is not a major pathogen in adult periodontitis and dento-alveolar abscesses.[ncbi.nlm.nih.gov]
  • These results confirm that P. micros may be involved in the aetiology of acute dentoalveolar abscesses and adult periodontitis.[ncbi.nlm.nih.gov]
  • This interaction represents a new mechanism that could promote the inflammatory response during periodontitis.[ncbi.nlm.nih.gov]
Dental Caries
  • Brain abscess complicating dental caries in children. Arch Pediatr. 1994;1:166-9. [ Links ] 12. Rosenthal ME, Rojtman AD, Frank E. Finegoldia magna (formerly Peptostreptococcus magnus): an overlooked etiology for toxic shock syndrome?.[scielo.br]
Foot Disease
  • This enzyme may be responsible for P. magnus playing a more central role in the pathogenesis of nonpuerperal breast abscess and diabetic foot disease than in intraabdominal sepsis.[ncbi.nlm.nih.gov]
  • This suggests that a conformational change occurs after the initial encounter complex is formed. The dissociation of the complex at equilibrium occurs in a single process of rate 0.095 s-1 at pH8.0 and 25 degrees C.[ncbi.nlm.nih.gov]
  • Findings suggested that P. micros can be involved in the pathogenesis of different forms of periradicular lesions.[ncbi.nlm.nih.gov]
  • These data strongly suggested that the DNA probe can be useful in the detection of P. micros and that this microorganism is important in certain periodontal and endodontic lesions.[ncbi.nlm.nih.gov]
  • The combined data suggest that both species possess large amounts of surface protein.[ncbi.nlm.nih.gov]
  • Our results suggest that the adherence of P. micros to epithelial cells is mediated by periodate-sensitive extracellular polysaccharides and that the protruding fibril-like protein surface structures of the rough type have an obstructive effect on the[ncbi.nlm.nih.gov]
  • (S. agalactiae, S. intermedius, S. mutans, S. sanguis I, and S. sanguis II). Only Peptostreptococcus anaerobius strains produced caproic and valeric acids in MNT broth cultures.[ncbi.nlm.nih.gov]
  • We describe a patient with postsurgical anaerobic meningitis due to Peptostreptococcus magnus.[ncbi.nlm.nih.gov]
  • Although anaerobic bacterial meningitis is uncommon, patients subjected to resection of head and neck malignancy appear at special risk.[ncbi.nlm.nih.gov]
  • Meningitis and epidural abscess related to pansinusitis. Pediatr Emerg Care. 2009;25:267-8. [ Links ] 9. Brook I. Meningitis and shunt infection caused by anaerobic bacteria in children. Pediatr Neurol. 2002;26:99-105. [ Links ] 10.[scielo.br]
  • The organism has been isolated in pure culture from a range of serious infections, including meningitis and endocarditis. However, isolation of Peptostreptococcus magnus from the oral cavity has rarely been attempted.[ncbi.nlm.nih.gov]
  • Most patients from whom microaerophilic streptococci were recovered in pure culture had abscesses (eg, dental, intracranial, pulmonary), bacteremia, meningitis, or conjunctivitis.[emedicine.com]


  • These findings point to starvation-survival capacity as a selection factor for microbial participation in post-treatment disease.[ncbi.nlm.nih.gov]
  • Protease treatment increased the adherence of the rough type of the level of the two other types. The adherence of all three types was reduced more than 85% by treatment with 10 mM sodium periodate.[ncbi.nlm.nih.gov]
  • In these cases, a 4-week course of parenteral penicillin/cefalosporin and metronidazole is the standard of treatment.[ncbi.nlm.nih.gov]
  • The patient's intraocular inflammation was not diminished by massive treatment with topical and systemic corticosteroid therapy or intravenously administered adrenocorticotropic hormone.[ncbi.nlm.nih.gov]
  • In this article, the authors report on a 72-year-old man in whom meningitis developed after extensive resection of the right sinuses for squamous cell carcinoma; initial treatment consisted of intravenous vancomycin and ceftazidime.[ncbi.nlm.nih.gov]


  • Article Sidebar Published: Mar 18, 2014 Clinical Cases Keywords Ocular infections, Severe prognosis in ocular infections, Endophthalmitis, Peptostreptococcus tetradius.[pagepressjournals.org]
  • Hence, pharmacotherapy for effective elimination of this potentially pathogenic microorganism can have a beneficial effect on the prognosis of root canal retreatments.[ijpsr.com]
  • The clinical picture, treatment and prognosis of meningitis due to anaerobic and nonfermentative bacteria. Rev Med Chir Soc Med Nat Iasi. 1999;103:158-60. [ Links ] 18. Walden JH, Hess B, Rigby M.[scielo.br]


  • The etiologies of splenic abscess should include Peptostreptococcus, and splenic abscesses should be added to the list of complications of cardiac catheterization.[ncbi.nlm.nih.gov]
  • Abstract P. micros is thought to be an important pathogen in the etiology of certain inflammatory lesions, however, the role of this microorganism is uncertain due to the lack of rapid and reliable method to identify this species.[ncbi.nlm.nih.gov]
  • Vancomycin, ceftriaxone plus metronidazole should be supplied when the etiological agent is unknown and drug resistance is probable 21 .[scielo.br]
  • The microbiology of pyogenic brain abscess has Staphylococcus and Streptococcus as the leading etiologic pathogens in immunocompetent individuals. Peptostreptococcus is also recognized as a common cause of brain abscess in this patient population.[mdpi.com]


  • These results demonstrate the genetic diversity of P. micros and the usefulness of AP-PCR for future epidemiological studies in understanding the role P. micros plays in periodontal disease pathogenesis.[ncbi.nlm.nih.gov]
  • Anaerobic infections (general): epidemiology of anaerobic infections . J Infect Chemother 17 ( Suppl 1 ): 4 – 12 . 26. Marina M ,, Strong CA ,, Civen R ,, Molitoris E ,, Finegold SM . 1993 .[asmscience.org]
Sex distribution
Age distribution


  • Depletion of reactive oxidative species by knockdown of TLR2 or TLR4, or incubation of cells with an antioxidant, prevented P anaerobius from inducing cholesterol biosynthesis and proliferation.[ncbi.nlm.nih.gov]
  • A patient's recovery from anaerobic infection depends on prompt and proper treatment according to the following principles: (1) neutralizing toxins produced by anaerobes, (2) preventing local bacterial proliferation by changing the environment, and (3[emedicine.medscape.com]
  • When Peptostreptococci and other anaerobes predominate, aggressive treatment of acute infection can prevent chronic infection.[en.wikipedia.org]

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