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Perianal Warts


Presentation

  • He presented 3 months postoperatively with constipation and inability to defecate. Examination revealed severe perianal stricture, which necessitated a defunctioning colostomy.[ncbi.nlm.nih.gov]
  • Fourteen boys (87.5%) presented with multiple moist papules and 2 boys (12.5%) presented with fleshy nodules. Eleven boys (68.75%) had a progressive course and 5 boys (31.25%) had a stationary course.[journal-ina.com]
  • If the immune system is compromised, they can present major problems to cure. The general principles of management of warts is presented in the menu below.[gpnotebook.co.uk]
  • Verrucous epidermal naevus should be included in the differential diagnosis of perianal warty lesions, particularly when they are present since birth or appear during childhood.[sti.bmj.com]
Weight Gain
  • Side effects of topical steroids in children may include problems with growth, weight gain, headaches, problems with vision, bulging soft spots on a baby's head, and stretch marks.[pharmaderm.com]
Hyperkeratosis
  • Histology of the forearm lesions revealed hyperkeratosis, papillomatosis, hypergranulosis, koilocytic changes in upper spinous layer and perivascular mononuclear cell infiltration in papillary dermis [Figure 2] a.[ijdvl.com]
  • Histological examination corroborated the clinical diagnosis by showing hyperkeratosis, acanthosis, and papillomatosis without any evidence of vacuolar change in the keratinocytes or any dermal pathology.[sti.bmj.com]
  • Other specified predominantly sexually transmitted diseases A64 Unspecified sexually transmitted disease A65 Nonvenereal syphilis A66.0 Initial lesions of yaws A66.1 Multiple papillomata and wet crab yaws A66.2 Other early skin lesions of yaws A66.3 Hyperkeratosis[icd10data.com]
  • Wart regression was reflected histopathologically by decreases in acanthosis, papillomatosis, granular vacuolation, and hyperkeratosis. Immunohistochemically, Ki-67 expression was markedly reduced, and a reversal of the CD4/CD8 ratio was seen.[telemedicine.org]
Skin Atrophy
  • atrophy (thinning), striae (lines on the skin), and miliaria (rash due to blocking of the sweat glands, 'prickly heat').[pharmaderm.com]
  • Steroid-based creams may be used very sparingly in severe chronic cases, but should not be applied on a long-term basis because of toxicities with skin atrophy and superinfection.[surgwiki.com]
Acneiform Eruption
  • Local adverse reactions that have been reported with topical corticosteroids include itching, irritation, dryness, folliculitis (swelling of the hair follicles), hypertrichosis (excessive hair growth), acneiform eruptions (acne or rashes resembling acne[pharmaderm.com]
Thin Skin
  • Description Condylomas in the anal region are most commonly found on the anoderm of the anal canal (the external part of the anal canal that has a thin skin lining) and also on the perianal skin which surrounds the anus.[colorectalsurgerynyc.com]
Neglect
  • Pediatric STDs remain a hidden and neglected problem. [15] Prevalence of childhood HPV infection varies widely in the studies. [16] There are different methods for evaluation of the circumstances of child sexual abuse which affecting the results.[journal-ina.com]
Neurologic Manifestation
  • Epidermodysplasia verruciformis with neurological manifestations. Int J Dermatol 1998;37:766-71. 6. Kim T, Park JC, Roh MR, Park JM, Kim SH, Cho NH, et al .[ijdvl.com]

Workup

Trichophyton Mentagrophytes
  • [back to top] OXISTAT Lotion Indication OXISTAT Lotion is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton[pharmaderm.com]
Trichophyton Rubrum
  • [back to top] OXISTAT Lotion Indication OXISTAT Lotion is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton[pharmaderm.com]

Treatment

  • Local reactions declined during continued treatment. CONCLUSIONS: The results indicate that Polyphenon E ointment is an efficacious and safe patient-applied topical treatment for external genital and perianal warts.[ncbi.nlm.nih.gov]

Prognosis

  • […] cases of HPV associated anal cancers are diagnosed in women, 1,700 in men Caucasian women are more likely than women of other races to have high risk HPV African American men are more likely than other races to have high risk HPV Prognostic factors Prognosis[pathologyoutlines.com]
  • […] for the infection to return, even after a successful treatment Please find comprehensive information on Condyloma Acuminatum regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis[dovemed.com]
  • POST-TREATMENT PROGNOSIS Mild pain and discomfort generally last for a few days. Pain medication may be prescribed. Patients treated in the clinic can return to work immediately.[fascrs.org]
  • Prognosis Once a diagnosis of anal warts has been made, further outbreaks can be controlled or sometimes prevented with proper care. Unfortunately, many cases of anal warts either fail to respond to treatment or recur.[encyclopedia.com]

Etiology

  • It provides a practical guide for the treatment of EGW, including epidemiology, etiology, clinical appearance, and diagnostic procedures for these viral infections.[ncbi.nlm.nih.gov]
  • PubMed View Article Google Scholar Frisch M: On the etiology of anal squamous carcinoma. Ugeskr Læger. 2002, 164 (17): 2302- Google Scholar Palefsky J: Human papillomavirus-related disease in people with HIV.[bmcresnotes.biomedcentral.com]
  • Second primary cancers following anal and cervical carcinoma: Evidence of shared etiologic factors. Am J Epidemiol 1992;136:54-58. 23. Williams AB, Darragh TM, Vranizan K, et al.[hivinsite.ucsf.edu]
  • In addition, HPV 6 and 11 are etiologic agents only of exophytic condyloma, whereas the other HPVs are etiologic agents of CIN with the segregation of specific HPVs in CIN III.[telemedicine.org]

Epidemiology

  • It provides a practical guide for the treatment of EGW, including epidemiology, etiology, clinical appearance, and diagnostic procedures for these viral infections.[ncbi.nlm.nih.gov]
  • Definition / general A benign hyperplastic squamous proliferation caused by the human papillomavirus Terminology Also called condyloma, verruca ( not the preferred term in the genital area), wart Epidemiology Associated with human papillomavirus (HPV)[pathologyoutlines.com]
  • Sexually transmitted papillomavirus infections: epidemiology, pathogenesis, clinic, morphology, important differential diagnostic aspects, current diagnostic and treatment options. An Bras Dermatol. 2009;84:377-89. [ Links ] 2.[scielo.br]
  • Molecular virology and epidemiology of human papillomavirus and cervical cancer. Cancer Epidemiol Biomarkers Prevent 1995;4:425-428. 6. Franco EL. Epidemiology of anogenital warts and cancer. Obstet Gynecol Clin North Am 1996;23(3):597-623. 7.[hivinsite.ucsf.edu]
Sex distribution
Age distribution

Pathophysiology

  • Ask about the pathophysiology of HPV wart, treatment outcome, success rates, cosmetics, before and after pictures, healing time, possible adverse effect of treatment, doctor's experience of treating genital warts and what do you need to do to protect[wartsclinic.com]
  • […] neoplasia Men and women with more than 10 female sex partners Patients with a history of anogenital warts or prior history of sexually transmitted diseases (STDs) Human immunodeficiency virus (HIV) infection Cigarette smoking Radiation therapy 13 , 14 PATHOPHYSIOLOGY[ncbi.nlm.nih.gov]

Prevention

  • Prevention Sexual abstinence and monogamous relationships can be the most effective form of prevention, and condoms may also decrease the chances of transmission of condyloma acuminata.[encyclopedia.com]
  • So the best way to prevent it is to not have sex (vaginal, oral, or anal). If someone does decide to have sex, using a condom every time for sex (vaginal, oral, anal) helps prevent HPV and other STDs.[kidshealth.org]

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