Presentation
This condition often presents in males of African American origin. This article describes the clinical presentation, diagnosis, and treatment of an Aboriginal Canadian male suffering from PCAS. [ncbi.nlm.nih.gov]
[More] An 18-year-old man presented for evaluation of a 1-year history of painful nodules on the scalp with associated hair loss. [gulfdoctor.net]
Entire Body System
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Fever
Psychogenic excoriation 651 205 Pyoderma gangrenosum 654 206 Pyogenic granuloma 659 207 Radiation dermatitis 662 208 Raynaud disease and phenomenon 665 209 Reactive arthritis 669 210 Relapsing polychondritis 673 211 Rhinophyma 677 212 Rocky Mountain spotted fever [books.google.com]
In September 2008, the condition worsened with the increase of the number of lesions and constitutional compromise with fever and arthralgia, initially managed at a periphery hospital center with clindamycin and intravenous oxacillin without improvement [colombiamedica.univalle.edu.co]
Less commonly, tender lymph nodes and/or fever may occur. The condition is usually diagnosed by a dermatologist after examination of your scalp, but in some cases, a biopsy under local anesthesia may be required for confirmation. [skinofcolorsociety.org]
Systemic symptoms also occur and include osteolytic bone lesions of the clavicle and sternum, fever, arthralgias, myalgias, and hepatosplenomegaly. Diagnosis is clinical. [accessemergencymedicine.mhmedical.com]
There was no history of recurrent fever or weight loss. There was no history of abnormal bowel movements or any other systemic complaints. There was no family history of similar complaints, though his father suffered from psoriasis. [idoj.in]
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Malaise
Regional lymphadenopathy, fever and malaise may be associated features. [docksci.com]
Skin
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Alopecia
Isotretinoin topical application assured successful control of the disease and averted the evolution of the clinical aspect to scarring alopecia and nodule formation. [ncbi.nlm.nih.gov]
Scarring alopecia or cicatricial alopecia results from follicular damage that is sufficient to cause the destruction and replacement of pilosebaceous structures by scar tissue. [pubfacts.com]
Acne vulgaris Classification and external resources … Wikipedia Alopecia areata — Classification and external resources Alopecia areata. ICD 10 L63 … Wikipedia [medicine.academic.ru]
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Chronic Dermatitis
DERMATITIS of the scalp characterized by the presence of large and small pus-filled, interconnected nodules, itching, and ALOPECIA. [purl.bioontology.org]
Face, Head & Neck
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Epistaxis
After this treatment, which continued for 3.5 months, and further reduction of the dose to 0.5 mg/kg of body weight because of the appearance of epistaxis and dryness in the ocular and buccal mucosae, a significant improvement of the clinical findings [ncbi.nlm.nih.gov]
Workup
Microbiology
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Treponema Pallidum
PCR failed to detect Treponema pallidum, Bartonella, Mycoplasma and Mycobacteria. A skin biopsy of the occipital region showed dissecting dermatitis with abscess formation (Fig. 2). The dermis was dominated by a neutrophilic inflammatory infiltrate. [medicaljournals.se]
HLA Type
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HLA-B27
Coexistence with acne conglobata or hidradenitis suppurativa is present in 1/3 of the cases, which implies a risk for developing seronegative spondyloarthropathies HLA-B27, with compromise of axial joints or asymmetric peripheral arthritis. [colombiamedica.univalle.edu.co]
Systemic Implications and Complications HLA B27-negative erosive and proliferative peripheral as well as axial arthropathy can be seen on radiologic examination of symptomatic patients. polyarthralgia may precede or follow the scalp disease. [dermatologyadvisor.com]
Treatment
The treatment has been well tolerated by the patient for 15 months at time of writing this report. [ncbi.nlm.nih.gov]
The treatment is usually difficult and often disappointing. In the case presented in the current work, the remission was achieved with nine-month isotretinoin treatment. [pubfacts.com]
Prognosis
In 2 patients, keratosis-ichthyosis-deafness (KID) syndrome has been reported to be associated with the follicular occlusion tetrad. [7, 8] Prognosis The prognosis for complete recovery from PCAS is poor. [thehealthscience.com]
The treatment measures may include the use of topical applications, oral medications, antibiotics, and cosmetic procedures, if necessary The prognosis of Dissecting Cellulitis of Scalp depends upon several factors including on the severity of the signs [dovemed.com]
The prognosis for complete recovery from PCAS is poor. [emedicine.medscape.com]
Etiology
Etiologic factors are unknown. Diagnosis is proven histologically. Management is very difficult and consists in systemic administration or intralesional injection of several drugs or in surgical manipulations. [ncbi.nlm.nih.gov]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
(See Etiology and Pathophysiology, Treatment, and Medication.) [1, 2] PCAS is an uncommon disease. [thehealthscience.com]
Epidemiology
From Etiology idiopathic Epidemiology occurs predominantly in black males in their second to fourth decade of life occurs less commonly in women & persons of different race Pathology dissecting cellulitis of the scalp Clinical-manifestations perifollicular [anvita.info]
AE...Micali G 2017 12 Epidemiology, clinical presentation and therapeutic approach in a multicentre series of dissecting cellulitis of the scalp. ( 27558283 ) Segurado-Miravalles G....VaA A -GalvA! [malacards.org]
There appears to be an association with acne conglobata and hidradenitis suppurativa, collectively known as the follicular occlusion triad, [115] or tetrad when also associated with pilonidal cysts. [20] Epidemiology Dissecting cellulitis of the scalp [medscape.com]
We discuss the diseases T related to the hair that may cause a red face and will present an update on their RI P epidemiology, clinics, pathogenesis, and therapy. [docksci.com]
Pathophysiology
(See Etiology and Pathophysiology, Treatment, and Medication.) [1, 2] PCAS is an uncommon disease. [thehealthscience.com]
Case Overview dissecting folliculitis Member Rated 0 Patient case no. 10926 Date added 02 February 2011 Patient details Age Adult Location Brazil Localisation Head / scalp Primary Lesions Cystic nodule Pathophysiology inflammatory skin appendage disorders [dermquest.com]
Indian Dermatol Online J 2014;5:491-3 Follicular occlusion tetrad is a complex consisting of four conditions having a similar pathophysiology. [idoj.in]
Prevention
An understanding of response to damaging agents is central to the problems of preventing or forestalling the early effects of aging in skin (a goal that is responsible for the current expansion in dermatological research). [books.google.com]
[…] several factors including on the severity of the signs and symptoms Please find comprehensive information on Dissecting Cellulitis of Scalp regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention [dovemed.com]
However, the lack of clinical studies regarding DC prevents full understanding of the disease and limits the ability to define a consensus treatment algorithm. [ncbi.nlm.nih.gov]