[…] flashes who don't want or can't take a hormonal therapy may get some relief from newer antidepressants such as Effexor (venlafaxine) or certain selective serotonin reuptake inhibitors (SSRIs), for example, Prozac (fluoxetine) and Paxil (paroxetine); the epilepsy [health.harvard.edu]

Symptoms of Major Depression Depressed, sad mood Decreased interest/pleasure in activities Significant weight loss/gain or decreased/increased appetite Insomnia or hypersomnia Psychomotor agitation or retardation Fatigue Feelings of worthlessness or excessive [ncbi.nlm.nih.gov]

Dry skin, dry eyes or dry mouth. Women who are still in the menopause transition (perimenopause) may also experience: Breast tenderness. Worsening of premenstrual syndrome (PMS). Irregular periods or skipping periods. [my.clevelandclinic.org]

[…] suggested that microdeletions of the long arm of the X chromosome might account for these observations. 8 The exact gene product encoded for at the distal end of the long arm of the X chromosome is unknown, but it presumably influences oocyte longevity [reliasmedia.com]

Nervousness Panic Fatigue Sadness Irritability Relationship Problems Insomnia Feeling Overwhelmed Distress Anger Hopelessness Inertia Fearfulness Impulsivity Low Self-Esteem Loneliness Worrying Despondency Decreased Libido Self-Doubt Forgetfulness Loss [medcraveonline.com]

Gabapentin (Neurontin) Gabapentin is a drug that modifies impulse transmission along the course of nerves. It is used primarily in people who have seizures or chronic pain conditions. [medicinenet.com]

In the brain, dopamine receptors mediate affect, attention, impulse control, decision-making, motor learning, sleep, reproductive behaviors, and the regulation of food intake [ 129 ]. [intechopen.com]

An inexpensive medicine called "Metformin" can be prescribed to help our insulin work better and to decrease inappropriate hunger. Night sweats Night sweats mean hot flush es (or hot flashes) that occur during sleep. [cemcor.ubc.ca]

In addition, estrogen production can affect the higher brain centers, which control appetite, so as to increase hunger. It is not uncommon for women in perimenopause to gain a significant amount of body fat. From 7. [medicinenet.com]

The degrees of distractibility and forgetfulness become intrusive and disruptive. Interest in sex decreases while there is an increased need for non-sexual contact. [medcraveonline.com]

Nocturia (feeling the need to get up in the night to urinate). Will I start menopause if I have a hysterectomy? During a hysterectomy, your uterus is removed. You won’t have a period after this procedure. [my.clevelandclinic.org]

Periods and pregnancy have their own lists of exasperating side effects: cramps, sciatica, children. The sole purpose of these earlier organic events is to prepare our bodies to propagate the species. Been there, done that. Washed a lot of T-shirts. [aarp.org]