METHODS: Referential recordings to stimuli consisting of photic stimulation presented in blocks were obtained. A total of 25 blocks, 15-stimuli each, were presented. Intrablock and interblock habituation effects were analyzed. [ncbi.nlm.nih.gov]

A moderate subdural effusion is present over the convexity. Caption: Semiaxial scan through anterior fontanelle. Description: Cystic changes of PVL are present in the perventricular white matter adjacent to the lateral ventricles. [sonoworld.com]

• Sudden Infant Death Syndrome

  When infants with PVL die at home, death seems sudden and unexpected. However, it is important to distinguish death caused by PVL from the Sudden Infant Death Syndrome because the implications for the family are quite different. [ncbi.nlm.nih.gov]

• Chronic Infection

  CONCLUSION: Periventricular leukomalacia has a significant but weak association with chronic diffuse capsular deciduitis and the presence of capsular decidual plasma cells, evidence of chronic infection but not histologic acute chorioamnionitis. [ncbi.nlm.nih.gov]

• Leg Weakness

  Nonspecific predictors of PVL include seizures, apnea, disturbed mental status, abnormal muscle tone, and leg weakness. [ncbi.nlm.nih.gov]

• Suggestibility

  It is suggested that serial real-time scanning be performed in neonates whose history suggests the possibility of hypoxic-ischemic brain injury. [ncbi.nlm.nih.gov]

[…] involved in neurosciences, as well as rehabilitation professionals, will be interested by this ensuing publication.The volume covers pathogenic aspects of brain lesions occurring in the fetal and neonatal period, and addresses the issues of diagnostic workup [books.google.ro]

• Hypsarrhythmia

  They showed similar clinical courses including oculoclonic seizure, hypsarrhythmia and severe mental retardation, in addition, to spastic quadriplegia. [ncbi.nlm.nih.gov]

• Epileptiform Activity

  KEYWORDS: cerebral palsy; preterm birth; sleep-potentiated epileptiform activity [ncbi.nlm.nih.gov]

• Ischemic Changes

  Periventricular leukomalacia (PVL) is a pathological entity characterized by ischemic changes in areas adjacent to the external angles of the lateral ventricles. It is associated with serious neurodevelopmental sequelae, especially spastic diplegia. [ncbi.nlm.nih.gov]

To evaluate the effect of antenatal steroid treatment on the development of neonatal periventricular leukomalacia. [ncbi.nlm.nih.gov]

Treatment There is no specific treatment for PVL. Treatment is symptomatic and supportive. Children with PVL should receive regular medical screenings to determine appropriate interventions. × Treatment There is no specific treatment for PVL. [ninds.nih.gov]

Treatment [ edit ] Current treatments [ edit ] Currently, there are no treatments prescribed for PVL. All treatments administered are in response to secondary pathologies that develop as a consequence of the PVL. [en.wikipedia.org]

Prognosis The prognosis for individuals with PVL depends upon the severity of the brain damage. [ninds.nih.gov]

Outlook (Prognosis) PVL often leads to nervous system and developmental problems in growing babies. These problems most often occur during the first to second year of life. [mountsinai.org]

PVL Prognosis Prognosis greatly depends upon the severity of the disease. While some children will have relatively minor problems, others may have severe disabilities and deficits for life. [birthinjuryguide.org]

It is suggested that echography is of value in the early diagnosis of this lesion which may be similar to intraparenchymal hemorrhage in its mechanism and prognosis. [ncbi.nlm.nih.gov]

Cerebral Palsy Etiology Etiology is the study of the causes and origins of diseases. Cerebral palsy etiology is the study of how cerebral palsy starts and what causes it. [childbirthinjuries.com]

[…] cesarean section, APGAR score, ante and postnatal indomethacin, acidosis, hypotension, tension pneumothorax, hypocarbia, oxygen dependency at 3 28 day) and infectious factors (premature rupture of membranes, chorioamnionitis, neonatal sepsis) in the etiology [nature.com]

The etiologic fraction is interpreted as the proportion of periventricular leukomalacia cases that are potentially preventable by administration of antenatal steroids. [journals.lww.com]

(Etiology) The exact cause of development of Periventricular Leukomalacia is currently unknown. [dovemed.com]

PVL has a poor prognosis because of its unclear etiology and pathogenesis. [spandidos-publications.com]

Author information 1 Department of Epidemiology and Biostatistics, Radboud University, Nijmegen, The Netherlands. [email protected] Abstract Intraventricular hemorrhage and cystic periventricular leukomalacia are often co-occurring characteristics [ncbi.nlm.nih.gov]

Developmental Epidemiology Network Investigators. Pediatr Res. 1999 Nov. 46(5):566-75. [Medline]. Liao SL, Lai SH, Chou YH, Kuo CY. [emedicine.medscape.com]

Pathophysiology The pathophysiology of periventricular leukomalacia is a complex process. Periventricular leukomalacia occurs because of ischemia induced injury to oligodendrocytes in the periventricular area of the developing brain. [emedicine.medscape.com]

Google Scholar | Crossref | Medline | ISI Hotchkiss RS, Karl IE : The pathophysiology and treatment of sepsis. N Engl J Med 2003 ;348: 138 — 150. [doi.org]

Supplementation of surfactant treatment with spD may be the key point in prevention of PVL by supression of inflammation and preventing damage to pre-OLs in a vulnerable premature brain operating through TLRs. [ncbi.nlm.nih.gov]

What research is being done to prevent PVL? Because PVL can’t be reversed, researchers are trying to find a way to prevent the loss of cells needed to form the white matter in the brain by using neuroprotective therapies. [hopefn3.org]

Is There Any Way to Prevent PVL? Since PVL can be caused by unknown factors, prevention can be difficult. [cerebralpalsyguidance.com]

Prevention and treatment of periventricular leukomalacia (PVL) Delaying premature birth, or preventing decreased oxygenation during an inevitable premature birth, is the most important step in decreasing the risk of PVL. [abclawcenters.com]