Presentation
We present examples showing the importance of 3D anatomic reconstruction of brain structures and MRI tractography for assessing white matter connectivity. [ncbi.nlm.nih.gov]
Minimally conscious state The patient has altered consciousness which is usually severe but there are aspects of awareness which are present, albeit inconsistently. [patient.info]
Workup
The SBU assessment stated: "[t]here is limited evidence that either visually rated EEG or qEEG helps the diagnostic workup differentiate AD (Alzheimer’s Disease) patients from controls or AD from other dementia disorders." [aetna.com]
EEG
- Generalized Periodic Patterns
EEG findings included normal, continuous generalized slowing, intermittent generalized slowing, background slowing, background suppression, alpha, generalized periodic pattern, PLEDS, and triphasic waves. [ncbi.nlm.nih.gov]
EEG findings included normal, continuous generalized slowing, intermittent generalized slowing, background slowing, background suppression, alpha, generalized periodic pattern, PLEDS… CONTINUE READING [semanticscholar.org]
- Triphasic Waves
EEG findings included normal, continuous generalized slowing, intermittent generalized slowing, background slowing, background suppression, alpha, generalized periodic pattern, PLEDS, and triphasic waves. [ncbi.nlm.nih.gov]
This may cause epileptiform changes, varying in type and extent, such as spiked triphasic waves or periodic or persistent epileptic activity ( 24 ). [tidsskriftet.no]
- Abnormal EEG
[…] to detect this, and the EEG only became abnormal in IPD at clinical onset. [aetna.com]
Treatment
These were conducted at baseline and after completion of the treatments. 3 children were enrolled. The Rancho assessment scales showed no change with treatment. [ncbi.nlm.nih.gov]
Two months after the start of the treatment, he was extubated and was able to say his name and address correctly. Six months after the start of treatment, he was transferred to another hospital to continue rehabilitation. [dx.doi.org]
Prognosis
Conflicting perspectives about the diagnosis and prognosis of the persistent vegetative state (PVS) as well as end-of-life (EOL) decision-making were disseminated in the Terri Schiavo case. [ncbi.nlm.nih.gov]
As therapies aimed at cerebral resuscitation and preservation following acute injury are developed and proved efficacious, prior guidelines for determining prognosis will require redefinition and reconfirmation. [accessmedicine.mhmedical.com]
Defining prognosis in medical coma. J Neurol Neurosurg Psychiatry 1991 ;54: 569 - 571 53. Shewmon DA, De Giorgio CM. Early prognosis in anoxic coma: reliability and rationale. Neurol Clin 1989 ;7: 823 - 843 54. Childs A. [doi.org]
Etiology
Median survival based on etiology varied from 3.0 to 8.6 years; no consistent relationship existed between etiology and duration of survival. [ncbi.nlm.nih.gov]
Traumatic brain injury and diffuse cerebral hypoxia are the most common etiologies. Patients in PVS may appear awake but are not aware or conscious, and they are unable to communicate with others or purposefully interact with their environment. [amboss.com]
Epidemiology
The epidemiology of pediatric head injuries: Data from a referral centre in Victoria, Australia. J Paediatr Child Health. 2009; May 28; 10 Egan J, Snyman N, Scheinberg N. et al. [doi.org]
[…] produced and regulated. [ 9 ] It is also important to determine whether patients in PDOC experience pain, and functional imaging may also be of help in this area. [ 10 ] There is consideration for the role of post-mortems in confirming the diagnosis - for epidemiological [patient.info]
Pathophysiology
To clarify the pathophysiological differences of the cerebrovascular reserve capacity in relation to cerebral cognitive impairments between persistent vegetative state (PVS) and vascular dementia (VD), we evaluated acetazolamide (ACZ) vasoreactivity testing [ncbi.nlm.nih.gov]
[…] brain injury Diffuse cerebral hypoxia Other causes of severe damage to the cerebral hemispheres and/or thalamus (e.g., neurodegenerative diseases, CNS infections, metabolic disturbances, toxins, developmental malformations of the CNS ) References: [1] Pathophysiology [amboss.com]
[…] and fractional anisotropy are related to the density, diameter and geometry of myelinated fibers.[10,23] We are using this technique to assess anatomical connectivity in PVS and MCS patients.[11] This is crucial for explaining and understanding the pathophysiology [medicc.org]
In the present article we seek to provide a principle understanding of electroencephalography (EEG), with an outline of the basic physiology and some simple pathophysiological observations. [tidsskriftet.no]
Prevention
Much of this research focuses on finding better ways to prevent and treat coma. [web.archive.org]
Heterogeneity of brain injury, consequences of long term minimal brain activity and potential factors that prevent recovery to consciousness are discussed. [ncbi.nlm.nih.gov]
Preventing blood clots includes use of drugs and compression or elevation of the person's legs. Moving the limbs, as occurs in passive-range-of-motion exercises, may also help prevent blood clots. [msdmanuals.com]