Most patients presenting to the ED with PCP intoxication do well and can be discharged home after a period of observation. [ncbi.nlm.nih.gov]

• Fever

  Fever, tachycardia and hypertension were frequent findings among the 25 patients with rhabdomyolysis and all had leukocytosis. The data show that rhabdomyolysis with and without acute renal failure is not infrequent among abusers of PCP. [ncbi.nlm.nih.gov]

  Fever, tachycardia and hypertension were frequent findings among the 25 patients with rhabdomyolysis and all had leukocytosis. The data show that rhabdomyolysis with and without acute renal failure is not infrequent among abusers of PCP. 1981 S. [karger.com]

  Misuse can cause blurred vision, body itching, rash, sweating, fever, hypertension, shallow respiration, diarrhea, toxic psychosis, coma, and an increase in heart rate, blood pressure, and body temperature. [www1.nyc.gov]

  Fever, tachycardia, and high blood pressure are frequent.[23] 3.2 Dose–effect relationship The 3-MeO-PCP doses and administration routes are not usually reported in the literature. [journals.lww.com]

  Many people find it unpleasantly reminiscent of fever dreams. [erowid.org]

• Hypersalivation

  Profuse diaphoresis, hypersalivation, bronchospasm, and urinary retention occurred in less than 5%. A small percentage had severe disturbances in vital signs, including three cases (0.3%) of cardiac arrest and 28 cases (2.8%) of apnea. [ncbi.nlm.nih.gov]

• Hypertension

  The prevalent clinical signs and symptoms were the following: retrograde amnesia, nystagmus, hypertension, and psychomotor agitation. Co-use of other substances was the norm. [ncbi.nlm.nih.gov]

  Antihypertensive agents are not usually needed, but diazoxide and hydralazine hydrochloride have been used to treat hypertensive crises. Diazepam and phenytoin have been used to treat seizures. [experts.umn.edu]

• Tachycardia

  Fever, tachycardia and hypertension were frequent findings among the 25 patients with rhabdomyolysis and all had leukocytosis. The data show that rhabdomyolysis with and without acute renal failure is not infrequent among abusers of PCP. [ncbi.nlm.nih.gov]

  Hypertension or tachycardia. Numbness or diminished responsiveness to pain. Ataxia. Dysarthria. Muscle rigidity. Seizures or coma. Hyperacusis. D. [dsm.wikia.com]

  Within an hour (less when smoked, "snorted," or used intravenously), two (or more) of the following signs: (1) vertical or horizontal nystagmus (2) hypertension or tachycardia (3) numbness or diminished responsiveness to pain (4) ataxia (5) dysarthria [behavenet.com]

  Tachycardia and mild hypertension are also seen with ketamine but are substantially less severe and unlikely to be life threatening. AUTONOMIC MANIFESTATIONS. Severe hyperthermia has been Observed and can be delayed, fatal, or both. [aibolita.com]

  Fever, tachycardia and hypertension were frequent findings among the 25 patients with rhabdomyolysis and all had leukocytosis. The data show that rhabdomyolysis with and without acute renal failure is not infrequent among abusers of PCP. 1981 S. [karger.com]

• Muscle Twitch

  Much less common are physical symptoms such as gastrointestinal distress, diaphoresis, chills, nausea, shakiness, muscle twitches, and increased blood pressure ( 102 ). [basicmedicalkey.com]

  Caffeine Mechanism adenosine antagonist decreased GABA activity (wakefulness) Intoxication presentation restlessness, insomnia diuresis muscle twitching cardiac arrhythmias treatment no specific treatment symptomatic treatment only Withdrawal presentation [medbullets.com]

  twitches.[19] Our patient did not report hallucinations or delusions but he was not specifically questioned about the presence or absence of these symptoms. [journals.lww.com]

• Miosis

  Other findings less frequent but still suspect are opisthotonos, hypertension, tachypnea or hyperpnea, miosis, hyperreflexia, hypertonia, and rigidity. Once suspected, the diagnosis is most easily made by finding PCP in the urine. [journals.sagepub.com]

• Euphoria

  Minor patterns included lethargy or stupor (38 cases; 3.8%), and combinations of bizarre behavior, violence, agitation, and euphoria in patients who were alert and oriented (325 cases; 32.5%). [ncbi.nlm.nih.gov]

  Within one hour, at least two of the following psychological symptoms: euphoria psychomotor agitation marked anxiety emotional lability grandiosity sensation of slowed time synesthesias D. [dsm.wikia.com]

  Signs of intoxication typically begin with enlarged pupils, euphoria, agitation, and increased heart rate and blood pressure. [usmleforum.com]

  Common syndromes seen in treatment settings include delirium, psychosis without delirium, catatonia, hypomania with euphoria, and depression with lethargy. [basicmedicalkey.com]

  Symptoms and Signs Intoxication, characterized by a giddy euphoria, occurs with lower doses; euphoria is often followed by bursts of anxiety or mood lability. [merckmanuals.com]

• Fear

  NOTHING – other than the fear of "taking a stand" – prevented these authors from offering a CONCLUSION strong enough to help to make a difference and save some lives. [charlydmiller.com]

  Here are some of the behavioral signs of PCP intoxication: “Poor perception of time and distance” Confusion Agitation Terror Panic Randomness in thought and action Severe anxiety and fear Mood swings Hostile and violent behavior PCP is increased in its [phencyclidine.org]

  Shelby told investigators that Crutcher refused repeated requests to stop and get on his knees and that she feared for her life, believing Crutcher was going to kill her, according to an affidavit filed with the manslaughter charge. [cbsnews.com]

  Shelby has said she fired her weapon because she feared for her life. Under Oklahoma law, first-degree manslaughter carries a minimum sentence of four years. She is scheduled to appear in court for a preliminary hearing on Nov. 29. [reuters.com]

  Such a NDE often results loss of the fear of death and a renewed interest in life. Production of artificial NDE's by ketamine has similarly been found effective to decrease an unatural fear of death. [lycaeum.org]

• Aggressive Behavior

  Symptoms in 11 patients suspected of phencyclidine intoxication included violent, aggressive behavior with delusions, hallucinations, agitation, and other signs of toxic psychosis. [ncbi.nlm.nih.gov]

  Benzodiazepines are usually effective in managing aggressive behavior. Anxiety and agitation can be managed by decreasing external stimuli such as noise, light, and touch. [emedicine.medscape.com]

  Hallucinations, euphoria, and suicidal impulses are also reported, as well as occasional aggressive behavior. [wiki.tripsit.me]

  Aggressive behaviors may occur with alcohol intoxication, but hallucinations are not seen (Galanter & Kleber, 2014). [theravive.com]

• Psychiatric Manifestation

  The physiologic and psychiatric manifestations of PCP intoxication are diverse and somewhat dose dependent. Urine acidification may hasten drug excretion. [ncbi.nlm.nih.gov]

  The psychiatric manifestations of Stage I intoxication can resemble a variety of psychiatric syndromes, making differential diagnosis difficult in the absence of toxicology results or a history of recent PCP, ketamine, or DXM intake. [basicmedicalkey.com]

• Agitation

  The prevalent clinical signs and symptoms were the following: retrograde amnesia, nystagmus, hypertension, and psychomotor agitation. Co-use of other substances was the norm. [ncbi.nlm.nih.gov]

  Within one hour, at least two of the following psychological symptoms: euphoria psychomotor agitation marked anxiety emotional lability grandiosity sensation of slowed time synesthesias D. [dsm.wikia.com]

• Seizure

  Diazepam and phenytoin have been used to treat seizures. Ion-trapping by continuous gastric suctioning and by urine acidification with ammonium chloride may increase clearance of PCP. [experts.umn.edu]

  Motor signs included grand mal seizures, generalized rigidity, localized dystonias, catalepsy, and athetosis. Profuse diaphoresis, hypersalivation, bronchospasm, and urinary retention occurred in less than 5%. [ncbi.nlm.nih.gov]

  Higher doses produce amnesia and coma, with analgesia sufficient for surgery, and seizures with respiratory depression occur at the highest doses. [dsm.wikia.com]

  With higher doses, symptoms can progress to sweating, tremors, confusion, hyperactivity, seizures, stroke, cardiac arrhythmias, and sudden death. At high doses of PCP, there is a drop in blood pressure, pulse rate, and respiration. [usmleforum.com]

• Nystagmus

  Clinical findings were the following: retrograde amnesia in 46 (25 %), horizontal nystagmus in 118 (64.1 %), vertical nystagmus in 90 (48.9 %), hypertension in 87 (47.3 %), and agitation in 71 (38.6 %). [ncbi.nlm.nih.gov]

  Nystagmus and bizarre and violent behavior may distinguish intoxication due to phencyclidine from that due to other substances. [dsm.wikia.com]

• Confusion

  Someone high on PCP may show signs of confusion and poor perception. PCP is a “bitter-tasting, white crystalline powder that is easy to dissolve in water or alcohol” ( NDIC ). [phencyclidine.org]

  With higher doses, symptoms can progress to sweating, tremors, confusion, hyperactivity, seizures, stroke, cardiac arrhythmias, and sudden death. At high doses of PCP, there is a drop in blood pressure, pulse rate, and respiration. [usmleforum.com]

  Signs of Phencyclidine Intoxication These are some of the common signs and symptoms of phencyclidine (PCP) intoxication: Desire to undress Belligerent behavior Hallucinations Confusion, amnesia Besides the obvious dangers of the above symptoms of being [gomentor.com]

  - disorientation, confusion without hallucinations, hallucinations or delusions, a catatonic-like syndrome, and/or coma) that develops during, or shortly after ingestion.[1] Epidemiology Prognosis Risk Factors Criterion A Recent use of phencyclidine [psychdb.com]

  Pharmacologic treatment is not necessary in most cases and may confuse the clinical picture. [basicmedicalkey.com]

• Ataxia

  Lower doses of phencyclidine produce vertigo, ataxia, nystagmus, mild hypertension, abnormal involuntary movements, slurred speech, nausea, weakness, slowed reaction times, euphoria or affective dulling, loquacity, and lack of concern. [dsm.wikia.com]

  Among the serious neurologic and medical complications are coma, trauma, infection, seizures, stroke, altered mentation, peripheral neuropathies, myelopathies, Parkinsonism, visual disturbances, dyskinesias, cerebellar ataxia, impotence, and fetal effects [books.google.com]

  Within an hour (less when smoked, "snorted," or used intravenously), two (or more) of the following signs: (1) vertical or horizontal nystagmus (2) hypertension or tachycardia (3) numbness or diminished responsiveness to pain (4) ataxia (5) dysarthria [behavenet.com]

  Although not conclusive or totally specific for PCP intoxication, the constellation of nystagmus, ataxia, and mild hypertension is typically observed even in mild, low-dose PCP intoxication. Treatment. [aibolita.com]

Proper diagnosis of PCP intoxication is important to ensure that rapid, appropriate treatment is given, costly diagnostic workups are avoided, and family evalua tions are instituted. [journals.sagepub.com]

Urine Toxicology and Laboratory Testing Generally when a patient appears to have PCP intoxication, regular laboratory workup should include renal function, fluid balance, electrolyte abnormalities, hypoglycemia, lactic acidosis, serum creatine phosphokinase [theravive.com]

• T Wave Inversion

  Electrocardiogram showed sinus rhythm with new deep biphasic T-wave inversions in anterolateral leads. Coronary angiography showed no pathological processes. Subsequently, ECG changes resolved coincidentally with the resolution of chest pain. [ncbi.nlm.nih.gov]

• Biphasic T Wave

  Electrocardiogram showed sinus rhythm with new deep biphasic T-wave inversions in anterolateral leads. Coronary angiography showed no pathological processes. Subsequently, ECG changes resolved coincidentally with the resolution of chest pain. [ncbi.nlm.nih.gov]

Abstract The history, symptoms, diagnosis and treatment of phencyclidine hydrochloride (PCP) intoxication and the pharmacology of PCP are reviewed. [ncbi.nlm.nih.gov]

The history, symptoms, diagnosis and treatment of phencyclidine hydrochloride (PCP) intoxication and the pharmacology of PCP are reviewed. [experts.umn.edu]

They also know about the various treatment options that are available - like psychotherapy and counseling. Unlike some others, they offer online treatment for help with an addiction to PCP. [gomentor.com]

- disorientation, confusion without hallucinations, hallucinations or delusions, a catatonic-like syndrome, and/or coma) that develops during, or shortly after ingestion.[1] Epidemiology Prognosis Risk Factors Criterion A Recent use of phencyclidine [psychdb.com]

Course and Prognosis. Complete recovery from PCP intoxication is the rule in the absence of major medical complications. [aibolita.com]

Even patients with confirmed acute myocardial infarction have a favorable prognosis, possibly because of their relatively young age and good underlying health ( 42 ). [basicmedicalkey.com]

Prognosis Relapse and return to PCP use is common, even among people who have experienced severe medical and psychiatric complications from the drug. [minddisorders.com]

Psychiatric symptoms that persist beyond a few days suggest an etiology other than stimulant use ( 24, 33, 34 ). Transient psychotic symptoms during periods of abstinence (“flashbacks”) have been reported among methamphetamine users ( 35 ). [basicmedicalkey.com]

- disorientation, confusion without hallucinations, hallucinations or delusions, a catatonic-like syndrome, and/or coma) that develops during, or shortly after ingestion.[1] Epidemiology Prognosis Risk Factors Criterion A Recent use of phencyclidine [psychdb.com]

There were no signs of liver or kidney failure (serum creatinine: 73 μmol/L; estimated glomerular filtration rate calculated according to the Chronic Kidney Disease Epidemiology Collaboration equation: 130 mL/minute/1.73 m2; prothrombin ratio: 99%; serum [journals.lww.com]

Neurological complications of drug abuse: pathophysiological mechanisms. Eur J Neurol 2000;7:595–606; Schuckit MA. Drug and alcohol abuse. A clinical guide to diagnosis and treatment, 6th ed. New York: Springer, 2006; Tashkin DP. [basicmedicalkey.com]

NOTHING – other than the fear of "taking a stand" – prevented these authors from offering a CONCLUSION strong enough to help to make a difference and save some lives. [charlydmiller.com]

For intoxication and PCP-induced psychotic disorder, although resolution of current symptoms and signs is paramount, the long-term goal of treatment is prevention of relapse to PCP use. [aibolita.com]

Treatment and aftercare will provide the skills and support someone in recovery will need to live a life of sobriety and prevent relapse. [drugabuse.com]

Staff may administer activated charcoal to prevent further absorption of any drugs from the digestive tract into the person’s system. Treatment of any seizures. Seizures will be controlled with medications. Heart monitoring. [recovery.org]

You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. [medlineplus.gov]