A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed. [ncbi.nlm.nih.gov]

• Intravenous Administration

  After the intravenous administration of phentolamine, a marked shortening of the H-H' interval was observed. This signifies an improvement in conduction at the bundle of His level. [ncbi.nlm.nih.gov]

  Phentolamine has a half-life in the blood of 19 minutes following intravenous administration. Approximately 13% of a single intravenous dose appears in the urine as unchanged drug. [medicineonline.com]

  […] phen·tol·a·mine test a test for pheochromocytoma; intravenous administration of phentolamine (5 mg) reduces hypertension due to a pheochromocytoma but not that due to other causes, for example, essential hypertension; the blood pressure is raised by the [medical-dictionary.thefreedictionary.com]

• Intravenous Drugs

  Separate data on the introduction of intravenous drug (10 mg in 20 ml isotonic sodium chloride solution; The speed of 1, 3 mg per minute or kapelno to 10 mg / h) as a peripheral vazodilatatora in acute heart failure and hypertension in acute heart attack [lekarstwo.ru]

  drug users,[45] and those undergoing chemotherapy,[46] whose veins can become sclerotic and difficult to access over time, sometimes forming a hard, painful “venous cord”. [en.wikipedia.org]

• Localized Pain

  pain in a few controls. [ncbi.nlm.nih.gov]

  Cardiovascular: Bradycardia (OraVerse 2% to 4%), hypertension (OraVerse Central nervous system: Mouth pain (OraVerse 19%), headache (OraVerse 6%), paresthesia (OraVerse Dermatologic: Facial swelling (OraVerse Gastrointestinal: Diarrhea (OraVerse Local [drugs.com]

• Wound Infection

  When epinephrine is accidentally discharged into a digit, ischemic skin necrosis resulting from the alpha-adrenergic blocking effects of this agent can lead to the need for multiple operations, wound infection, and even loss of the digit. [ncbi.nlm.nih.gov]

• Sepsis

  However, pathogens may also enter the bloodstream, causing sepsis, which can be sudden and life-threatening. A central IV line poses a higher risk of sepsis, as it can deliver bacteria directly into the central circulation. [en.wikipedia.org]

• Recurrent Abdominal Pain

  A 37-year-old opiate-tolerant female with a history of recurrent abdominal pain, gastroparesis, cyclic vomiting syndrome, and migraine headaches was admitted to the emergency department (ED) with severe acute abdominal pain, nausea, and vomiting. [ncbi.nlm.nih.gov]

• Severe Abdominal Pain

  Gastroparesis represents a difficult treatment challenge because management of gastric dysmotility and the accompanying severe abdominal pain is often mutually exacerbating and ineffective. [ncbi.nlm.nih.gov]

• Formication

  Chromatographic separation was carried out on an Acquity UPLC BEH C18 column using an isocratic mobile phase system composed of acetonitrile and 1% formic acid in water (33:67, v/v) at a flow rate of 0.45 mL/min. [ncbi.nlm.nih.gov]

• Myofascial Trigger Point

  CONCLUSIONS: The results support the hypothesis that the autonomic nervous system is involved in the pathogenesis of myofascial trigger points. [ncbi.nlm.nih.gov]

• Distractibility

  923 dental visits where local anesthetic was administered, a standardized form was used to gain further information and identify any complications; this was accompanied by a questionnaire for the student's teacher, in order to quantify the student's distraction [ncbi.nlm.nih.gov]

  […] consider using the anterolateral thigh as an injection site in infants under one year old.[23] To help infants and children cooperate with injection administration, the Advisory Committee on Immunization Practices in the United States recommends using distractions [en.wikipedia.org]

• Female Sexual Dysfunction

  Abstract It was found that the light emission produced by the oxidation of luminol by potassium ferricyanide in the basic medium was enhanced by phentolamine, a drug recently used to treatment of male and female sexual dysfunction. [ncbi.nlm.nih.gov]

The Tmax for lidocaine occurred later and the Cmax for lidocaine was slightly higher when comparing the 4L2P treatment and the 4L treatment. [ncbi.nlm.nih.gov]

Outlook (Prognosis) Most people who have noncancerous tumors that are removed with surgery are still alive after 5 years. The tumors come back in some people. Levels of the hormones norepinephrine and epinephrine return to normal after surgery. [mountsinai.org]

MATERIALS AND METHODS: After a comprehensive evaluation 44 patients with recent onset (less than 3 years) of erectile dysfunction and a high likelihood of organogenic etiology underwent a prospective, double-blind and placebo controlled trial with oral [ncbi.nlm.nih.gov]

[…] of ED (organic or psychogenic) the most common form of ED has a mixture of organic and psychogenic origins. 3 Because of the complex etiology of ED, multiple approaches may be necessary to successfully treat the majority of individuals with the disorder [nature.com]

Etiology and management". American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. 3 (1): 21–31. doi:10.2165/00129784-200303010-00003. PMID 14727943. [en.wikipedia.org]

Beijing: 2010 15 Liu CC, Tseng HW, Wang SM, Wang JR and Su IJ: An outbreak of enterovirus 71 infection in Taiwan, 1998: Epidemiologic and clinical manifestations. J Clin Virol. 17:23–30. 2000. [spandidos-publications.com]

^ "Pinkbook | Vaccine Administration | Epidemiology of VPDs | CDC". www.cdc.gov. 25 September 2019. Retrieved 12 September 2020. ^ "Epinephrine Injection". MedlinePlus. Last revised 03/15/2017 ^ Zimmermann PG (February 2010). [en.wikipedia.org]

A case of ruptured pheochromocytoma is presented, the pathophysiology discussed, and the literature reviewed. [ncbi.nlm.nih.gov]

Circulating and/or locally released catecholamines may activate platelets directly via α-adrenoceptor stimulation during stressful physiological and pathophysiological conditions in humans. adrenaline α-adrenoceptors lipolysis phentolamine platelet aggregability [clinsci.org]

Such results provide a pathway for the development of a prevention strategy for ED. [ncbi.nlm.nih.gov]

Prevention or control of hypertensive episodes in the patient with pheochromocytoma. [medicineonline.com]

Its mesylate salt is used intravenously or intramuscularly to prevent and treat hypertension occurring before and during surgery for pheochromocytoma and is also used intravenously to prevent and treat cutaneous necrosis and sloughing when extravasation [medical-dictionary.thefreedictionary.com]

Diagnosis of pheochromocytoma and to prevent or control hypertensive episodes prior to or during pheochromocytomectomy. Prevention of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine. [robholland.com]