Presentation
A photoallergic reaction generally presents as an eczema (also called dermatitis ) confined to the areas in contact with the responsible chemical and exposed to the sun. [dermnetnz.org]
In addition, hyper- and hypopigmentation are present together, resulting in a polymorphous skin presentation. There have also been severe cases accompanied by fever and a reduced general condition. [ncbi.nlm.nih.gov]
Skin
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Eczema
In extreme cases artificial lighting at work can also contribute to continued persistence of the eczema. [ncbi.nlm.nih.gov]
A photoallergic reaction generally presents as an eczema (also called dermatitis ) confined to the areas in contact with the responsible chemical and exposed to the sun. [dermnetnz.org]
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Hyperpigmentation
Occasionally, however, persistent hyperpigmentation develops. In these cases laser therapy (Rubin laser) can help. Photoallergic dermatitis Photoallergic reactions occur, unlike phototoxicity, only if a specific sensitization has been acquired. [ncbi.nlm.nih.gov]
Neurologic
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Confusion
Their differential diagnosis is problematic not only because of similar phenotypes, but also because of confusing nomenclature and classification. [ncbi.nlm.nih.gov]
Treatment
Treatment Treatment is very difficult. The treatment of choice is thalidomide, the use of which must be examined in depth considering the serious adverse reactions (teratogenicity, irreversible neuropathies). [ncbi.nlm.nih.gov]
Phytophotocontact dermatitis What is the treatment for photocontact dermatitis ? The main goal of treatment is to identify the photosensitising agent and if possible to avoid touching it. [dermnetnz.org]
Etiology
They are referred to as idiopathic primary photodermatoses if the etiology is unknown ( 1, 2 ). [ncbi.nlm.nih.gov]
Epidemiology
Larger series have been described in England and Scandinavia although precise epidemiological data are lacking. A familial variant is present in indigenous peoples in North and Latin America ( 15 ). [ncbi.nlm.nih.gov]
Pathophysiology
Repeated solar radiation leads to light hardening that can probably be ascribed to exhaustion of the pathophysiological steps and which is used therapeutically. [ncbi.nlm.nih.gov]
Prevention
Prevention is just as important as treatment. Many diseases are directly or indirectly provoced or exacerbated by sunlight. [ncbi.nlm.nih.gov]