In addition, hyper- and hypopigmentation are present together, resulting in a polymorphous skin presentation. There have also been severe cases accompanied by fever and a reduced general condition. [ncbi.nlm.nih.gov]

A photoallergic reaction generally presents as an eczema (also called dermatitis ) confined to the areas in contact with the responsible chemical and exposed to the sun. [dermnetnz.org]

• Inflammation

  An interesting new approach to preventative external therapy involves topical application of suitable antioxidants, because pathophysiologically the inflammation reactions are most likely mediated by free radicals generated in the skin. [ncbi.nlm.nih.gov]

• Fever

  There have also been severe cases accompanied by fever and a reduced general condition. Differential diagnosis Erythropoietic and hepatic porphyrias must be excluded by determining the level of porphyrins in the blood and urine. [ncbi.nlm.nih.gov]

• Eczema

  Synonym(s) Dermatitis phototoxic; Eczema phototoxic; Photocontact dermatitis; Phototoxic contact eczema; Phototoxic dermatitis; Phototoxic eczema; Phototoxic reaction Definition This section has been translated automatically. [altmeyers.org]

  In extreme cases artificial lighting at work can also contribute to continued persistence of the eczema. [ncbi.nlm.nih.gov]

  A photoallergic reaction generally presents as an eczema (also called dermatitis ) confined to the areas in contact with the responsible chemical and exposed to the sun. [dermnetnz.org]

• Hyperpigmentation

  Often it is only the "cosmetically disturbing" residual hyperpigmentations that lead to a visit to the doctor. Amiodarone leads to grey-blue colour changes of the skin. [altmeyers.org]

  Occasionally, however, persistent hyperpigmentation develops. In these cases laser therapy (Rubin laser) can help. Photoallergic dermatitis Photoallergic reactions occur, unlike phototoxicity, only if a specific sensitization has been acquired. [ncbi.nlm.nih.gov]

• Petechiae

  Induction of erythema and wheals after radiation with UV-A Differential diagnosis Erythropoietic protoporphyria (diffuse swellings with petechiae rather than wheals, pain, no pruritus), urticarial phototoxic reaction after taking medication, physical [ncbi.nlm.nih.gov]

Treatment Treatment is very difficult. The treatment of choice is thalidomide, the use of which must be examined in depth considering the serious adverse reactions (teratogenicity, irreversible neuropathies). [ncbi.nlm.nih.gov]

Phytophotocontact dermatitis What is the treatment for photocontact dermatitis ? The main goal of treatment is to identify the photosensitising agent and if possible to avoid touching it. [dermnetnz.org]

They are referred to as idiopathic primary photodermatoses if the etiology is unknown ( 1, 2 ). [ncbi.nlm.nih.gov]

Larger series have been described in England and Scandinavia although precise epidemiological data are lacking. A familial variant is present in indigenous peoples in North and Latin America ( 15 ). [ncbi.nlm.nih.gov]

Repeated solar radiation leads to light hardening that can probably be ascribed to exhaustion of the pathophysiological steps and which is used therapeutically. [ncbi.nlm.nih.gov]

Prevention is just as important as treatment. Many diseases are directly or indirectly provoced or exacerbated by sunlight. [ncbi.nlm.nih.gov]