We present here the case of a 40 year old women presenting an augmentation over one month of the volume of her right breast with an ulcerated mass measuring 25cm. The clinical characteristics were in favor as a malignant tumor. [ncbi.nlm.nih.gov]

Previous cases have shown phylloides tumors to present in the third trimester as large masses that require mastectomy. [ingentaconnect.com]

Homepage Rare diseases Search Search for a rare disease Phyllodes tumor of the breast Disease definition Phyllode tumor of the breast is a rare fibroepithelial neoplasm accounting for less than 1% of all mammary tumors, usually presenting in adult females [orpha.net]

Snap Shot A 68-year-old female immigrant from Mexico presents with a massively enlarged left breast. A fine needle aspiration was performed and the cytology came back as negative. [medbullets.com]

• Flushing

  After acquisition of a native scan, gadopentetate dimeglumine (0.1 mmol/kg of body weight, Magnevist, Schering) was administered IV as a rapid bolus within 10 sec followed by a 20-mL saline flush. [ajronline.org]

• Absent Deep Tendon Reflex

  Her neurological examination revealed grade 1 power in right upper and lower limbs with absent deep tendon reflexes. [ccij-online.org]

Learn more about the steps of diagnosis, including: Digital mammography Ultrasound MRI Staging workup (for malignant tumors) Biopsy Pathology What is the treatment for Phyllodes tumors? Phyllodes tumors are treated by complete excision. [hopkinsmedicine.org]

At the initial workup of the primi her radiological workups were negative for distant metastasis. After 12 months postsurgery the patient was admitted for right chest pain and left pelvic pain. [ijpmonline.org]

Electrodiagnostics: Electrical testing of the nerves and spinal cord may be performed as part of a diagnostic workup. [panamacityspine.com]

A panel of cytokeratins (CKs) (CKAE1/AE3, CK5/6, 34βE12, cam 5.2) and myoepithelial marker p63 24 should be used for the workup because of variable staining patterns in metaplastic (sarcomatoid) carcinomas. [archivesofpathology.org]

I did not have radiotherapy or chemotherapy treatments. I had difficulty finding others with my disease and conclusive information about treatment for the disease, so I had to read the scant research and make my own treatment decisions. [story.rare-cancer.org]

Treatment and Surgery for Phyllodes Tumors Phyllodes Tumors - Follow Up Care [news-medical.net]

An appropriate method of treatment, as well as their prognosis, remains under dispute. In the majority of cases, the course of the disease is mild and surgical treatment results in long-term survival. [journals.lww.com]

Treatments Surgery to remove a Phyllodes tumor is the standard treatment. This type of tumor does not respond well to radiation, chemotherapy or hormonal therapies. If your tumor is relatively small and benign, it may be removed with a lumpectomy. [verywellhealth.com]

No series has shown radiation therapy to be of benefit in the primary treatment of PT. Based on anecdotal experience, adjuvant radiotherapy may be appropriate treatment of locally recurrent PT in selected cases. [cancerjournal.net]

These subtypes are able to better predict the prognosis of the patient, Barrio explained. These malignant tumors, which are considered a sarcoma, are primarily treated by surgery and can recur locally. [onclive.com]

Prognosis Your prognosis, or outlook after treatment, is very good for a benign Phyllodes tumor. There is a low chance of recurrence for a Phyllodes tumor if you are 45 or older. [verywellhealth.com]

Mastectomy Radiation What is the prognosis for Phyllodes tumors? Prognosis is excellent for benign phyllodes tumors. [hopkinsmedicine.org]

Prognosis is good unless metastases (usually pulmonary) are present. Click here for Patient Education NOTE: This is the Professional Version. [msdmanuals.com]

The relationship between tumor size and prognosis is not clear. [jtd.amegroups.com]

Causes - Cystosarcoma phyllodes breast The etiology of CSP is unknown. Prevention - Cystosarcoma phyllodes breast Not supplied. Diagnosis - Cystosarcoma phyllodes breast Prognosis - Cystosarcoma phyllodes breast Not supplied. [checkorphan.org]

Epidemiology 1% of breast tumors Average age 45 years (age 25 - 30 years in Asians, Aust N Z J Surg 1988;58:301 ) Rare in children or men (gynecomastia is more likely) More common in Hispanics, particularly if born in Latin America ( Cancer 1993;71:3020 ) Etiology [pathologyoutlines.com]

The etiology of phyllodes tumors is unknown. Because of limited data, the relative percentages of benign and malignant phyllodes tumors are not well defined. [emedicine.medscape.com]

(Etiology) The exact cause of development of Benign Phyllodes Tumor of Breast is currently not clearly understood Studies have shown that such tumors may be caused by hormonal influence What are the Signs and Symptoms of Benign Phyllodes Tumor of Breast [dovemed.com]

Definition / general Phyllodes tumors with increased mitotic activity, stromal overgrowth, atypia and infiltrative borders Epidemiology 10% of phyllodes tumors; very rare under age 20 years Clinical features Aggressive with local recurrence, 3 - 22% metastasize [pathologyoutlines.com]

IMPAKT 2016 Breast Cancer Conference May 12-14, Brussels, Belgium 28. 3 rd Conference on Epidemiology and Infectious Diseases June 1-3, Nanjing, China 29. 33 rd Annual Miami Breast Cancer Conference March 10-13, Miami, USA List of Society/Associations [conferenceseries.com]

The descriptive epidemiology of malignant cystosarcoma phyllodes tumors of the breast. Cancer 1993;71:3020–4. [3]. Guerrero MA, Ballard BR, Grau AM. [journals.lww.com]

The descriptive epidemiology of malignant cystosarcoma phyllodes tumors of the breast. Cancer. 1993; 71 (10):3020–3024. [ PubMed ] [ Google Scholar ] 4. Fiks A. Cystosarcoma phyllodes of the mammary gland—Muller's tumor. [ncbi.nlm.nih.gov]

Pathophysiology and Etiology Phyllodes tumor is the most commonly occurring nonepithelial neoplasm of the breast, though it represents only about 1% of tumors in the breast. [3] It has a smooth, sharply demarcated texture and typically is freely movable [emedicine.medscape.com]

Cystosarcoma phylloides: epidemiology, pathophysiology, pathobiology, diagnosis, therapy and survival. Arch Gynaecol. 1985; 236 :173–81. doi: 10.1007/BF02133961. [ PubMed ] [ CrossRef ] Tan EY, Tan PH, Yong WS, Wong HB, Ho GH, Yeo AW, Wong CY. [ncbi.nlm.nih.gov]

Luke’s International Hospital, 9-1 Akashi-cho, Chuo-ku Tokyo, 104-8560, Japan (2) Department of Molecular Medicine and Pathophysiology, Osaka Medical Center for Cancer and Cardiovascular Disease, 1-3-3 Nakamichi, Higashinari-ku Osaka, 537-8511, Japan [surgicalcasereports.springeropen.com]

Prevention - Cystosarcoma phyllodes breast Not supplied. Diagnosis - Cystosarcoma phyllodes breast Prognosis - Cystosarcoma phyllodes breast Not supplied. [checkorphan.org]

Benign Phyllodes Tumor of Breast is difficult to prevent. Since prevention is generally not possible, it is important to be aware of the risk factors for breast lumps and take steps to avoid them. [dovemed.com]

Surgery helps prevent future tumors and complications from the existing tumor. The label benign may help put a woman at ease about the tumor not being cancerous or harmful. [medicalnewstoday.com]

Local therapy is aimed at preventing the tumor from coming back in the breast. Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it. [hopkinsmedicine.org]