Presentation
In seven cases (39%), a light pruritus was present, without any other associated symptoms. [ncbi.nlm.nih.gov]
We present a unique case of LPP that was characterized by an atypical initial inflammatory phase and subsequent circinate lesions with central clearing. Similar articles Coexistence of nail lichen planus and lichen planus pigmentosus. [pubmed.ncbi.nlm.nih.gov]
There is epidermic atrophy with irregular hydropic degeneration on the basal layer and an absence of epidermic hyperplasia (usually present on lichen planus). [scielo.br]
In addition, the patient presented alopecia in the frontotemporal region with hairline recession, isolated terminal hairs (compatible with lonely hair sign), complete alopecia of the eyebrows, and partial alopecia of the eyelashes, onset of which coincided [actasdermo.org]
Differential diagnosis Lichenoid drug reaction: Lichenoid interface infiltrate with basal cell squamatization and Civatte bodies Distinguishing features from lichen planus: clinical history of potential culprit medication present and eosinophils generally [pathologyoutlines.com]
Treatment
Treatment Lichen planus on the skin often clears up on its own in months to years. If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. [mayoclinic.org]
The following entities were considered in the differential diagnosis: exogenous ochronosis, ashy dermatosis, Riehl melanosis, and melasma.Clinical Course and Treatment Prior to diagnosis, the patient had received intermittent treatment with 4% hydroquinone [actasdermo.org]
Afterwards, we initiated treatment with systemic corticoid using prednisone 20mg/day for 30 days, without any therapeutic response. [ncbi.nlm.nih.gov]
[…] neck areas (An Bras Dermatol 2019;94:378) 63 year old man with a pruritic eruption following a Blaschkoid distribution (JAAD Case Rep 2020;6:237) 66 year old man with a pruritic eruption following radiation therapy (Dermatol Online J 2019;25:13030) Treatment [pathologyoutlines.com]
Etiology
The etiology is unknown. The described pattern indicates a lichenoid-like immunological reaction to an as-yet-unknown agent or stimulus. [actasdermo.org]
The etiology is unknown, without any causal relation to medications or sun exposure. [ncbi.nlm.nih.gov]
[…] esophagus (rare) May be confined to oral mucosa (J Dent Res Dent Clin Dent Prospects 2010;4:3) Pathophysiology Possible delayed hypersensitivity reaction (Int J Dermatol 2009;48:682) Cytotoxic CD8+ lymphocytes lead to apoptosis of basal keratinocytes Etiology [pathologyoutlines.com]
The etiology is unknown, without any causal relation to medications or sun exposure. The pathogenesis appears to be related to a T lymphocyte-mediated, cytotoxic activity against basal keratinocytes.11. Gaertner E, Elstein W. [scielo.br]
Epidemiology
[…] plaques Sawtoothed rete ridges, band-like lymphohistiocytic infiltrate at the dermoepidermal junction Wedge shaped hypergranulosis Civatte bodies (dyskeratotic keratinocytes) ICD coding ICD-10: L43.8 - other lichen planus ICD-11: EA91 - lichen planus Epidemiology [pathologyoutlines.com]
Pathophysiology
Dermatol 2004;151:1172) Sites Skin (flexor, wrists and forearms, dorsal hands, shins, presacral area), mucous membranes (oral mucosa, genitalia), hair, nails, esophagus (rare) May be confined to oral mucosa (J Dent Res Dent Clin Dent Prospects 2010;4:3) Pathophysiology [pathologyoutlines.com]
Prevention
Clinical trials Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. [mayoclinic.org]