Pilocarpus (Pilocarpus Vahl): Symptoms, Diagnosis and Treatment

[…] were present mainly in the intermediary leaves, and the three new alkaloids were mainly found in the leaflets and petioles.[ncbi.nlm.nih.gov]
The seven species analyzed had different imidazole alkaloid profiles, but only one did not present quantifiable pilocarpine contents in its leaves. The Pilocarpus genus shows potential for the prospection of novel alkaloids.[agris.fao.org]
Little by little they were discovering new properties and discarding others that had been attributed up to the present era, in which exploit its properties as a cholinergic agent, ie, activates the parasympathetic nervous system.[mtplantas.com]

Images Distribution Full Distribution Listing Native to: Argentina Northeast, Aruba, Belize, Bolivia, Brazil North, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Colombia, Costa Rica, Cuba, Dominican Republic, El Salvador, French[plantsoftheworldonline.org]

Interestingly, a positive side effect of reported use of the pilocarpine eye solution drug was an improvement in sleep apnea and snoring in glaucoma patients using the drug.[rain-tree.com]

The oral preparations of Pilocarpus microphyllus (Jaborandi), like jaborandi powder, are utilized as a diaphoretic and for the treatment of diarrhea. Topically - As a topical application, jaborandi is utilized for the treatment of glaucoma.[amazondiscovery.com]
Pilocarpus use may cause many side effects, including an increase in heart rate, headaches, nausea, dehydration, flushing, vomiting, contracted pupils, excessive sweating or salivation, stomach irritation, bradycardia, and diarrhea.[wisegeek.com]
Both, however, appear to increase peristalsis and in full doses may cause a persistent watery diarrhea, with straining or tormina after the diarrhea ceases.[henriettes-herb.com]
Despite serious safety concerns, jaborandi is used to treat diarrhea and to cause sweating . Some people also put it in the eye to treat glaucoma . It’s important to understand the difference between jaborandi and pilocarpine .[webmd.com]

Primer [repetitions] a Polymorphic loci 844 [(CT) 8 RC] 14 CHRIS [(CA) 7 YG] 13 DAT [(GA) 7 RG] 9 ISSR-4 [(AC) 8 YT] 9 ISSR-6 [(AG) 8 YT] 8 843 [(CT) 8 RA] 9 JOHN [(AG) 7 YC] 5 MANNY [(CAC) 4 RC] 10 MAO [(CTC) 4 RC] 12 OMAR [(GAG) 4 RC] 14 TERRY [(GTG[ncbi.nlm.nih.gov]

By instillations, he employs it as a powerful myotic in mydriasis , and prefers it to eserine, as it is accompanied with no irritation.[henriettes-herb.com]

[…] rheumatism , but in which the endocarditis was aggravated (Fereol)—this author has also observed an attack of gout, and an increase of the intensity of hemicrania, in cases where it was administered; in the albuminuria of pregnancy its use was followed with hematuria[henriettes-herb.com]

By 1876, Jaborandi leaves were being employed in Europe in the treatment of many diseases including fever, stomatitis, colitis, laryngitis, bronchitis, influenza, pneumonia, and psoriasis.[rain-tree.com]

Extensive modern research has borne out the efficacy of many of these treatments. The leaves contain a number of medically active constituents, including alkaloids; an essential oil; terpenes and tannic acid[ ].[tropical.theferns.info]

The sweating may be prevented or checked by the subcutaneous injection of 1-100 of a grain of atropine. --from Parke, Davis & Co. Organic Materia Medica. Detroit, MI: Parke, Davis & Company; 1888., pg. 103-104.[stars.library.ucf.edu]
People also use it to prevent hair loss. Neurosis, diabetes, hepatitis, and pneumonia are also treated with pilocarpus. The plant is more commonly known as jaborandi.[wisegeek.com]
[ ] Other Uses The leaves are used as a hair tonic which is believed to open pores and clean hair follicles, prevent hair loss, and generally aid in the manageability of hair[ ].[tropical.theferns.info]

Pilocarpus